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Protein

C-X-C motif chemokine

Gene

Cxcl10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-X-C motif chemokineUniRule annotation
Gene namesi
Name:Cxcl10Imported
Synonyms:Scyb10Imported
ORF Names:mCG_12531Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1352450 Cxcl10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21UniRule annotationAdd BLAST21
ChainiPRO_501420587422 – 98C-X-C motif chemokineUniRule annotationAdd BLAST77

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000034855
ExpressionAtlasiQ548V9 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ548V9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 89SCYInterPro annotationAdd BLAST63

Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J1VC Eukaryota
ENOG410ZTJK LUCA
HOVERGENiHBG107789
KOiK12671
OMAiRCTCIKI
OrthoDBiEOG091G0YSL

Family and domain databases

CDDicd00273 Chemokine_CXC, 1 hit
InterProiView protein in InterPro
IPR001089 Chemokine_CXC
IPR018048 Chemokine_CXC_CS
IPR001811 Chemokine_IL8-like_dom
IPR033899 CXC_Chemokine_domain
IPR036048 Interleukin_8-like_sf
PANTHERiPTHR10179 PTHR10179, 1 hit
PfamiView protein in Pfam
PF00048 IL8, 1 hit
PRINTSiPR00437 SMALLCYTKCXC
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00471 SMALL_CYTOKINES_CXC, 1 hit

Sequencei

Sequence statusi: Complete.

Q548V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPSAAVIFC LILLGLSGTQ GIPLARTVRC NCIHIDDGPV RMRAIGKLEI
60 70 80 90
IPASLSCPRV EIIATMKKND EQRCLNPESK TIKNLMKAFS QKRSKRAP
Length:98
Mass (Da):10,789
Last modified:May 24, 2005 - v1
Checksum:i42B0E6A0CC56FE36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227743 mRNA Translation: AAG10400.1
AK144279 mRNA Translation: BAE25810.1
AK150765 mRNA Translation: BAE29832.1
AK151210 mRNA Translation: BAE30205.1
AK151415 mRNA Translation: BAE30380.1
AK151534 mRNA Translation: BAE30481.1
AK152568 mRNA Translation: BAE31320.1
AK152814 mRNA Translation: BAE31517.1
AK153181 mRNA Translation: BAE31783.1
AK157130 mRNA Translation: BAE33973.1
AK157139 mRNA Translation: BAE33975.1
AK157589 mRNA Translation: BAE34130.1
AK157678 mRNA Translation: BAE34149.1
AK172540 mRNA Translation: BAE43058.1
CH466617 Genomic DNA Translation: EDL05256.1
RefSeqiNP_067249.1, NM_021274.2
UniGeneiMm.877

Genome annotation databases

GeneIDi15945
KEGGimmu:15945

Similar proteinsi

Entry informationi

Entry nameiQ548V9_MOUSE
AccessioniPrimary (citable) accession number: Q548V9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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