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Protein

C-X-C motif chemokine

Gene

Cxcl10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

CytokineUniRule annotationSAAS annotation

Keywords - Biological processi

ChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-X-C motif chemokineUniRule annotation
Gene namesi
Name:Cxcl10Imported
Synonyms:Scyb10Imported
ORF Names:mCG_12531Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1352450. Cxcl10.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121UniRule annotationAdd
BLAST
Chaini22 – 9877C-X-C motif chemokineUniRule annotationPRO_5007750954Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000034855.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047646.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini27 – 8963SCYInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J1VC. Eukaryota.
ENOG410ZTJK. LUCA.
GeneTreeiENSGT00530000063958.
HOVERGENiHBG107789.
KOiK12671.
OMAiRCTCIKI.
OrthoDBiEOG091G0YSL.

Family and domain databases

InterProiIPR001089. Chemokine_CXC.
IPR018048. Chemokine_CXC_CS.
IPR027220. Chemokine_CXCL10.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PANTHERiPTHR10179. PTHR10179. 1 hit.
PTHR10179:SF47. PTHR10179:SF47. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
PRINTSiPR00437. SMALLCYTKCXC.
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00471. SMALL_CYTOKINES_CXC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q548V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPSAAVIFC LILLGLSGTQ GIPLARTVRC NCIHIDDGPV RMRAIGKLEI
60 70 80 90
IPASLSCPRV EIIATMKKND EQRCLNPESK TIKNLMKAFS QKRSKRAP
Length:98
Mass (Da):10,789
Last modified:May 24, 2005 - v1
Checksum:i42B0E6A0CC56FE36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227743 mRNA. Translation: AAG10400.1.
AK144279 mRNA. Translation: BAE25810.1.
AK150765 mRNA. Translation: BAE29832.1.
AK151210 mRNA. Translation: BAE30205.1.
AK151415 mRNA. Translation: BAE30380.1.
AK151534 mRNA. Translation: BAE30481.1.
AK152568 mRNA. Translation: BAE31320.1.
AK152814 mRNA. Translation: BAE31517.1.
AK153181 mRNA. Translation: BAE31783.1.
AK157130 mRNA. Translation: BAE33973.1.
AK157139 mRNA. Translation: BAE33975.1.
AK157589 mRNA. Translation: BAE34130.1.
AK157678 mRNA. Translation: BAE34149.1.
AK172540 mRNA. Translation: BAE43058.1.
CH466617 Genomic DNA. Translation: EDL05256.1.
RefSeqiNP_067249.1. NM_021274.2.
UniGeneiMm.877.

Genome annotation databases

GeneIDi15945.
KEGGimmu:15945.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF227743 mRNA. Translation: AAG10400.1.
AK144279 mRNA. Translation: BAE25810.1.
AK150765 mRNA. Translation: BAE29832.1.
AK151210 mRNA. Translation: BAE30205.1.
AK151415 mRNA. Translation: BAE30380.1.
AK151534 mRNA. Translation: BAE30481.1.
AK152568 mRNA. Translation: BAE31320.1.
AK152814 mRNA. Translation: BAE31517.1.
AK153181 mRNA. Translation: BAE31783.1.
AK157130 mRNA. Translation: BAE33973.1.
AK157139 mRNA. Translation: BAE33975.1.
AK157589 mRNA. Translation: BAE34130.1.
AK157678 mRNA. Translation: BAE34149.1.
AK172540 mRNA. Translation: BAE43058.1.
CH466617 Genomic DNA. Translation: EDL05256.1.
RefSeqiNP_067249.1. NM_021274.2.
UniGeneiMm.877.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047646.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15945.
KEGGimmu:15945.

Organism-specific databases

CTDi3627.
MGIiMGI:1352450. Cxcl10.

Phylogenomic databases

eggNOGiENOG410J1VC. Eukaryota.
ENOG410ZTJK. LUCA.
GeneTreeiENSGT00530000063958.
HOVERGENiHBG107789.
KOiK12671.
OMAiRCTCIKI.
OrthoDBiEOG091G0YSL.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034855.

Family and domain databases

InterProiIPR001089. Chemokine_CXC.
IPR018048. Chemokine_CXC_CS.
IPR027220. Chemokine_CXCL10.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PANTHERiPTHR10179. PTHR10179. 1 hit.
PTHR10179:SF47. PTHR10179:SF47. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
PRINTSiPR00437. SMALLCYTKCXC.
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00471. SMALL_CYTOKINES_CXC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ548V9_MOUSE
AccessioniPrimary (citable) accession number: Q548V9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.