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Protein
Submitted name:

MCG4302, isoform CRA_c

Gene

Socs2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG4302, isoform CRA_cImported
Submitted name:
Suppressor of cytokine signaling 2Imported
Submitted name:
Suppressor of cytokine signaling SOCS2Imported
Submitted name:
Suppressor of cytokine signaling-2Imported
Gene namesi
Name:Socs2Imported
Synonyms:Cish2Imported
ORF Names:mCG_4302Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1201787. Socs2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000020027.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020215.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 156109SH2InterPro annotationAdd
BLAST
Domaini151 – 19747SOCS boxInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains SOCS box domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG4566. Eukaryota.
ENOG4111V4J. LUCA.
GeneTreeiENSGT00760000119136.
HOVERGENiHBG002457.
KOiK04695.
OMAiHLYLNKP.
OrthoDBiEOG091G0J75.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR028410. SOCS2.
IPR001496. SOCS_box.
[Graphical view]
PANTHERiPTHR24369:SF75. PTHR24369:SF75. 1 hit.
PfamiPF00017. SH2. 1 hit.
PF07525. SOCS_box. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00253. SOCS. 1 hit.
SM00969. SOCS_box. 1 hit.
[Graphical view]
SUPFAMiSSF158235. SSF158235. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50225. SOCS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q548Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRCLEPSG NGADRTRSQW GTAGLPEEQS PEAARLAKAL RELSQTGWYW
60 70 80 90 100
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ
110 120 130 140 150
DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL
160 170 180 190
YLTKPLYTSA PTLQHFCRLA INKCTGTIWG LPLPTRLKDY LEEYKFQV
Length:198
Mass (Da):22,434
Last modified:May 24, 2005 - v1
Checksum:iC9051AE9C84BA7F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106153 mRNA. Translation: AAI06154.1.
AF292933 Genomic DNA. Translation: AAL76097.1.
AE016773 Genomic DNA. Translation: AAN84618.1.
AK137403 mRNA. Translation: BAE23343.1.
AK160537 mRNA. Translation: BAE35854.1.
AK162591 mRNA. Translation: BAE36978.1.
CH466539 Genomic DNA. Translation: EDL21600.1.
CH466539 Genomic DNA. Translation: EDL21602.1.
CH466539 Genomic DNA. Translation: EDL21603.1.
RefSeqiNP_001162126.1. NM_001168655.1.
NP_001162127.1. NM_001168656.1.
NP_001162128.1. NM_001168657.1.
NP_031732.1. NM_007706.4.
XP_011241712.1. XM_011243410.1.
UniGeneiMm.474283.
Mm.490329.

Genome annotation databases

GeneIDi216233.
KEGGimmu:216233.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106153 mRNA. Translation: AAI06154.1.
AF292933 Genomic DNA. Translation: AAL76097.1.
AE016773 Genomic DNA. Translation: AAN84618.1.
AK137403 mRNA. Translation: BAE23343.1.
AK160537 mRNA. Translation: BAE35854.1.
AK162591 mRNA. Translation: BAE36978.1.
CH466539 Genomic DNA. Translation: EDL21600.1.
CH466539 Genomic DNA. Translation: EDL21602.1.
CH466539 Genomic DNA. Translation: EDL21603.1.
RefSeqiNP_001162126.1. NM_001168655.1.
NP_001162127.1. NM_001168656.1.
NP_001162128.1. NM_001168657.1.
NP_031732.1. NM_007706.4.
XP_011241712.1. XM_011243410.1.
UniGeneiMm.474283.
Mm.490329.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020215.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi216233.
KEGGimmu:216233.

Organism-specific databases

CTDi8835.
MGIiMGI:1201787. Socs2.

Phylogenomic databases

eggNOGiKOG4566. Eukaryota.
ENOG4111V4J. LUCA.
GeneTreeiENSGT00760000119136.
HOVERGENiHBG002457.
KOiK04695.
OMAiHLYLNKP.
OrthoDBiEOG091G0J75.

Enzyme and pathway databases

UniPathwayiUPA00143.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020027.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR028410. SOCS2.
IPR001496. SOCS_box.
[Graphical view]
PANTHERiPTHR24369:SF75. PTHR24369:SF75. 1 hit.
PfamiPF00017. SH2. 1 hit.
PF07525. SOCS_box. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00253. SOCS. 1 hit.
SM00969. SOCS_box. 1 hit.
[Graphical view]
SUPFAMiSSF158235. SSF158235. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50225. SOCS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ548Q7_MOUSE
AccessioniPrimary (citable) accession number: Q548Q7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.