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Protein
Submitted name:

MCG4302, isoform CRA_c

Gene

Socs2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
MCG4302, isoform CRA_cImported
Submitted name:
Suppressor of cytokine signaling 2Imported
Submitted name:
Suppressor of cytokine signaling SOCS2Imported
Gene namesi
Name:Socs2Imported
Synonyms:Cish2Imported
ORF Names:mCG_4302Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1201787 Socs2

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiQ548Q7

Expressioni

Gene expression databases

BgeeiENSMUSG00000020027
ExpressionAtlasiQ548Q7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ548Q7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 156SH2InterPro annotationAdd BLAST109
Domaini151 – 197SOCS boxInterPro annotationAdd BLAST47

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566 Eukaryota
ENOG4111V4J LUCA
HOVERGENiHBG002457
KOiK04695
OMAiHLYLNKP
OrthoDBiEOG091G0J75

Family and domain databases

CDDicd10383 SH2_SOCS2, 1 hit
Gene3Di3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR028410 SOCS2
IPR035862 SOCS2_SH2
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR44396 PTHR44396, 1 hit
PfamiView protein in Pfam
PF00017 SH2, 1 hit
PF07525 SOCS_box, 1 hit
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 1 hit
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS50001 SH2, 1 hit
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

Q548Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRCLEPSG NGADRTRSQW GTAGLPEEQS PEAARLAKAL RELSQTGWYW
60 70 80 90 100
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ
110 120 130 140 150
DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL
160 170 180 190
YLTKPLYTSA PTLQHFCRLA INKCTGTIWG LPLPTRLKDY LEEYKFQV
Length:198
Mass (Da):22,434
Last modified:May 24, 2005 - v1
Checksum:iC9051AE9C84BA7F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106153 mRNA Translation: AAI06154.1
AF292933 Genomic DNA Translation: AAL76097.1
AE016773 Genomic DNA Translation: AAN84618.1
AK137403 mRNA Translation: BAE23343.1
AK160537 mRNA Translation: BAE35854.1
AK162591 mRNA Translation: BAE36978.1
CH466539 Genomic DNA Translation: EDL21600.1
CH466539 Genomic DNA Translation: EDL21602.1
CH466539 Genomic DNA Translation: EDL21603.1
RefSeqiNP_001162126.1, NM_001168655.1
NP_001162127.1, NM_001168656.1
NP_001162128.1, NM_001168657.1
NP_031732.1, NM_007706.4
XP_011241712.1, XM_011243410.2
UniGeneiMm.474283
Mm.490329

Genome annotation databases

GeneIDi216233
KEGGimmu:216233

Similar proteinsi

Entry informationi

Entry nameiQ548Q7_MOUSE
AccessioniPrimary (citable) accession number: Q548Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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