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Protein
Submitted name:

MCG4302, isoform CRA_c

Gene

Socs2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG4302, isoform CRA_cImported
Submitted name:
Suppressor of cytokine signaling 2Imported
Submitted name:
Suppressor of cytokine signaling SOCS2Imported
Gene namesi
Name:Socs2Imported
Synonyms:Cish2Imported
ORF Names:mCG_4302Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1201787. Socs2.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiQ548Q7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020027.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ548Q7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 156SH2InterPro annotationAdd BLAST109
Domaini151 – 197SOCS boxInterPro annotationAdd BLAST47

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4566. Eukaryota.
ENOG4111V4J. LUCA.
HOVERGENiHBG002457.
KOiK04695.
OMAiHLYLNKP.
OrthoDBiEOG091G0J75.

Family and domain databases

CDDicd10383. SH2_SOCS2. 1 hit.
Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR000980. SH2.
IPR036860. SH2_dom_sf.
IPR028410. SOCS2.
IPR035862. SOCS2_SH2.
IPR001496. SOCS_box.
IPR036036. SOCS_box-like_dom_sf.
PANTHERiPTHR44396. PTHR44396. 1 hit.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PF07525. SOCS_box. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SM00253. SOCS. 1 hit.
SM00969. SOCS_box. 1 hit.
SUPFAMiSSF158235. SSF158235. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.
PS50225. SOCS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q548Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRCLEPSG NGADRTRSQW GTAGLPEEQS PEAARLAKAL RELSQTGWYW
60 70 80 90 100
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ
110 120 130 140 150
DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL
160 170 180 190
YLTKPLYTSA PTLQHFCRLA INKCTGTIWG LPLPTRLKDY LEEYKFQV
Length:198
Mass (Da):22,434
Last modified:May 24, 2005 - v1
Checksum:iC9051AE9C84BA7F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106153 mRNA. Translation: AAI06154.1.
AF292933 Genomic DNA. Translation: AAL76097.1.
AE016773 Genomic DNA. Translation: AAN84618.1.
AK137403 mRNA. Translation: BAE23343.1.
AK160537 mRNA. Translation: BAE35854.1.
AK162591 mRNA. Translation: BAE36978.1.
CH466539 Genomic DNA. Translation: EDL21600.1.
CH466539 Genomic DNA. Translation: EDL21602.1.
CH466539 Genomic DNA. Translation: EDL21603.1.
RefSeqiNP_001162126.1. NM_001168655.1.
NP_001162127.1. NM_001168656.1.
NP_001162128.1. NM_001168657.1.
NP_031732.1. NM_007706.4.
XP_011241712.1. XM_011243410.2.
UniGeneiMm.474283.
Mm.490329.

Genome annotation databases

GeneIDi216233.
KEGGimmu:216233.

Similar proteinsi

Entry informationi

Entry nameiQ548Q7_MOUSE
AccessioniPrimary (citable) accession number: Q548Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)