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Protein
Submitted name:

Vacuolar protein sorting 28 (Yeast), isoform CRA_a

Gene

VPS28

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Vacuolar protein sorting 28 (Yeast), isoform CRA_aImported
Submitted name:
Vacuolar protein sorting 28-like protein isoform 1Imported
Submitted name:
Vacuolar sorting protein 28Imported
Gene namesi
Name:VPS28Imported
ORF Names:hCG_24005Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38512.

Expressioni

Gene expression databases

BgeeiENSG00000160948.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
BLZF1Q9H2G93EBI-10243107,EBI-2548012
CARD9Q9H2573EBI-10243107,EBI-751319
GOLGA2Q083793EBI-10243107,EBI-618309
HEL25V9HWG03EBI-10243107,EBI-10183977
INCA1Q0VD863EBI-10243107,EBI-6509505
MBIPQ9NS73-53EBI-10243107,EBI-10182361
PNMA5Q96PV43EBI-10243107,EBI-10171633
RASSF5Q8WWW03EBI-10243107,EBI-367390
SAXO1Q8IYX73EBI-10243107,EBI-3957636
SKILP127573EBI-10243107,EBI-2902468
SMN2Q166373EBI-10243107,EBI-395421
TCF12Q990813EBI-10243107,EBI-722877
TCF4P158843EBI-10243107,EBI-533224
TRIM27P143733EBI-10243107,EBI-719493
TRIM54Q9BYV23EBI-10243107,EBI-2130429
USHBP1Q8N6Y03EBI-10243107,EBI-739895
VPS37BQ9H9H43EBI-10243107,EBI-4400866
VPS52Q8N1B43EBI-10243107,EBI-2799833

Protein-protein interaction databases

STRINGi9606.ENSP00000366565.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 120VPS28 N-terminalInterPro annotationAdd BLAST108
Domaini124 – 220VPS28 C-terminalInterPro annotationAdd BLAST97

Phylogenomic databases

eggNOGiKOG3284. Eukaryota.
ENOG4111IQ4. LUCA.
HOVERGENiHBG054248.
KOiK12184.
OMAiKYRLDCP.

Family and domain databases

InterProiIPR007143. VPS28.
IPR017899. VPS28_C.
IPR017898. VPS28_N.
[Graphical view]
PANTHERiPTHR12937. PTHR12937. 1 hit.
PfamiPF03997. VPS28. 1 hit.
[Graphical view]
PIRSFiPIRSF017535. VPS28. 1 hit.
PROSITEiPS51310. VPS28_C. 1 hit.
PS51313. VPS28_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q548N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHGIPATPG IGAPGNKPEL YEEVKLYKNA REREKYDNMA ELFAVVKTMQ
60 70 80 90 100
ALEKAYIKDC VSPSEYTAAC SRLLVQYKAA FRQVQGSEIS SIDEFCRKFR
110 120 130 140 150
LDCPLAMERI KEDRPITIKD DKGNLNRCIA DVVSLFITVM DKLRLEIRAM
160 170 180 190 200
DEIQPDLREL METMHRMSHL PPDFEGRQTV SQWLQTLSGM SASDELDDSQ
210 220
VRQMLFDLES AYNAFNRFLH A
Length:221
Mass (Da):25,425
Last modified:May 24, 2005 - v1
Checksum:iB2E1697B82D02AB8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei221Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF316887 mRNA. Translation: AAK00314.1.
KU178635 mRNA. Translation: ALQ34093.1.
CH471162 Genomic DNA. Translation: EAW82094.1.
CH471162 Genomic DNA. Translation: EAW82100.1.
RefSeqiNP_057292.1. NM_016208.3.
UniGeneiHs.418175.
Hs.650693.

Genome annotation databases

GeneIDi51160.
KEGGihsa:51160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF316887 mRNA. Translation: AAK00314.1.
KU178635 mRNA. Translation: ALQ34093.1.
CH471162 Genomic DNA. Translation: EAW82094.1.
CH471162 Genomic DNA. Translation: EAW82100.1.
RefSeqiNP_057292.1. NM_016208.3.
UniGeneiHs.418175.
Hs.650693.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366565.

Protocols and materials databases

DNASUi51160.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi51160.
KEGGihsa:51160.

Organism-specific databases

CTDi51160.
PharmGKBiPA38512.

Phylogenomic databases

eggNOGiKOG3284. Eukaryota.
ENOG4111IQ4. LUCA.
HOVERGENiHBG054248.
KOiK12184.
OMAiKYRLDCP.

Miscellaneous databases

ChiTaRSiVPS28. human.
GenomeRNAii51160.

Gene expression databases

BgeeiENSG00000160948.

Family and domain databases

InterProiIPR007143. VPS28.
IPR017899. VPS28_C.
IPR017898. VPS28_N.
[Graphical view]
PANTHERiPTHR12937. PTHR12937. 1 hit.
PfamiPF03997. VPS28. 1 hit.
[Graphical view]
PIRSFiPIRSF017535. VPS28. 1 hit.
PROSITEiPS51310. VPS28_C. 1 hit.
PS51313. VPS28_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ548N1_HUMAN
AccessioniPrimary (citable) accession number: Q548N1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.