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Protein
Submitted name:

Septin 6

Gene

SEPT6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Septin 6Imported
Submitted name:
Septin 6, isoform CRA_eImported
Submitted name:
cDNA FLJ77872, highly similar to Homo sapiens SEPTIN6 type V (SEPTIN6) mRNAImported
Gene namesi
Name:SEPT6Imported
ORF Names:hCG_23191Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000125354.22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134941944

PTM / Processingi

Proteomic databases

MaxQBiQ548C9

Expressioni

Gene expression databases

BgeeiENSG00000125354
ExpressionAtlasiQ548C9 baseline and differential

Structurei

3D structure databases

SMRiQ548C9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305Septin-type GInterPro annotationAdd BLAST267

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili321 – 341Sequence analysisAdd BLAST21
Coiled coili343 – 399Sequence analysisAdd BLAST57

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2655 Eukaryota
COG5019 LUCA
HOVERGENiHBG065093

Family and domain databases

CDDicd01850 CDC_Septin, 1 hit
InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030644 SEPT6
IPR016491 Septin
PANTHERiPTHR18884:SF55 PTHR18884:SF55, 1 hit
PfamiView protein in Pfam
PF00735 Septin, 1 hit
PIRSFiPIRSF006698 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q548C9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE
60 70 80 90 100
TGLGKSTLMD TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV
110 120 130 140 150
STVGFGDQIN KEDSYKPIVE FIDAQFEAYL QEELKIRRVL HTYHDSRIHV
160 170 180 190 200
CLYFIAPTGH SLKSLDLVTM KKLDSKVNII PIIAKADAIS KSELTKFKIK
210 220 230 240 250
ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS TEELKIGNKM
260 270 280 290 300
MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV
360 370 380 390 400
KEKEAELKEA EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK
410 420
TAAELLQSQG SQAGGSQTLK RDKEKKNFF
Length:429
Mass (Da):49,167
Last modified:February 5, 2008 - v1
Checksum:i3D8EE2EB88E30838
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF397023 mRNA Translation: AAN76547.1
AK290977 mRNA Translation: BAF83666.1
CH471161 Genomic DNA Translation: EAW89855.1
RefSeqiNP_665801.1, NM_145802.3
UniGeneiHs.496666

Genome annotation databases

GeneIDi23157
UCSCiuc004ert.4 human

Similar proteinsi

Entry informationi

Entry nameiQ548C9_HUMAN
AccessioniPrimary (citable) accession number: Q548C9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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