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Q54800 (CAP3C_STREE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UTP--glucose-1-phosphate uridylyltransferase

EC=2.7.7.9
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene names
Name:cap3C
Synonyms:cps3U
OrganismStreptococcus pneumoniae
Taxonomic identifier1313 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathway

Carbohydrate metabolism; nucleotide-sugar metabolism.

Capsule biogenesis; capsule polysaccharide biosynthesis.

Sequence similarities

Belongs to the UDPGP type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306UTP--glucose-1-phosphate uridylyltransferase
PRO_0000201365

Experimental info

Sequence conflict2041N → H in AAC43313. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q54800 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: F8E243D00F47EEA8

FASTA30633,919
        10         20         30         40         50         60 
MKKVKKAVIP AAGLGTRFLP ATKALAKEML PIVDRPTIHF VIEEALRSGI EDILVVTGKS 

        70         80         90        100        110        120 
KRSIEDYFDS TFELEYSLRK QGKMELLKSV NESTDIKVHF VRQSSPRGLG DAVLQAKSFV 

       130        140        150        160        170        180 
GDDPFVVMLG DDLMDITDST AVPLTRQLMD DYNATQASTI AVMPVRYEDV SSYGVISPRL 

       190        200        210        220        230        240 
ESSNGLYSVD AFVEKPKPEE APSNLAIIGR YLLTPEIFSI LETQKPGAGN EIQLTDAIDT 

       250        260        270        280        290        300 
LNKTQSVFAR EFVGKRYDVG DKFNFMKTSI DYALQHPQIK ESLKNYVIAL GKQLEKLDDC 


SSSGHL 

« Hide

References

[1]"Sequence and transcriptional analysis of a DNA region involved in the production of capsular polysaccharide in Streptococcus pneumoniae type 3."
Arrecubieta C., Garcia E., Lopez R.
Gene 167:1-7(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 406 / Type 3.
[2]"Characterization of the cassette containing genes for type 3 capsular polysaccharide biosynthesis in Streptococcus pneumoniae."
Dillard J.P., Vandersea M.W., Yother J.
J. Exp. Med. 181:973-983(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: WU2 / Serotype 3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z47210 Genomic DNA. Translation: CAA87405.1.
U15171 Genomic DNA. Translation: AAC43313.1.

3D structure databases

ProteinModelPortalQ54800.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00215.
UPA00934.

Family and domain databases

Gene3D3.90.550.10. 1 hit.
InterProIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMSSF53448. SSF53448. 1 hit.
TIGRFAMsTIGR01099. galU. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAP3C_STREE
AccessionPrimary (citable) accession number: Q54800
Secondary accession number(s): Q54612
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways