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Protein
Submitted name:

Insulin-like growth factor 1

Gene

Igf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor 1Imported
Gene namesi
Name:Igf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96432. Igf1.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 127105Sequence analysisPRO_5004249352Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiQ547V2.

Expressioni

Gene expression databases

BgeeiQ547V2.
GenevisibleiQ547V2. MM.

Structurei

3D structure databases

ProteinModelPortaliQ547V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 8359IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000233362.
HOVERGENiHBG006137.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q547V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSHLFYLA LCLLTFTSST TAGPETLCGA ELVDALQFVC GPRGFYFNKP
60 70 80 90 100
TGYGSSIRRA PQTGIVDECC FRSCDLRRLE MYCAPLKPTK AARSIRAQRH
110 120
TDMPKTQKEV HLKNTSRGSA GNKTYRM
Length:127
Mass (Da):14,120
Last modified:May 24, 2005 - v1
Checksum:i1054B8CAC72DC2D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF440694 mRNA. Translation: AAL34535.1.
UniGeneiMm.268521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF440694 mRNA. Translation: AAL34535.1.
UniGeneiMm.268521.

3D structure databases

ProteinModelPortaliQ547V2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ547V2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96432. Igf1.

Phylogenomic databases

HOGENOMiHOG000233362.
HOVERGENiHBG006137.

Miscellaneous databases

ChiTaRSiIgf1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ547V2.
GenevisibleiQ547V2. MM.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Construction of a robust CHO cell-line for biopharmaceutical production."
    Lai D.-Z.
    Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.

Entry informationi

Entry nameiQ547V2_MOUSE
AccessioniPrimary (citable) accession number: Q547V2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.