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Protein
Submitted name:

SLCA22A3

Gene

Slc22a3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SLCA22A3Imported
Submitted name:
Solute carrier family 22 (Organic cation transporter), member 3Imported
Gene namesi
Name:Slc22a3Imported
Synonyms:Slca22a3Imported
ORF Names:mCG_16686Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1333817. Slc22a3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 42HelicalSequence analysisAdd BLAST22
Transmembranei151 – 170HelicalSequence analysisAdd BLAST20
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Transmembranei203 – 225HelicalSequence analysisAdd BLAST23
Transmembranei237 – 258HelicalSequence analysisAdd BLAST22
Transmembranei264 – 283HelicalSequence analysisAdd BLAST20
Transmembranei345 – 363HelicalSequence analysisAdd BLAST19
Transmembranei375 – 396HelicalSequence analysisAdd BLAST22
Transmembranei403 – 422HelicalSequence analysisAdd BLAST20
Transmembranei428 – 451HelicalSequence analysisAdd BLAST24
Transmembranei463 – 483HelicalSequence analysisAdd BLAST21
Transmembranei489 – 512HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000023828.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024595.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 517MFSInterPro annotationAdd BLAST424

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IRIE. Eukaryota.
ENOG410XSRI. LUCA.
HOVERGENiHBG061545.
KOiK08200.
OMAiCQRYLLE.
OrthoDBiEOG091G05AC.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004749. Orgcat_transp/SVOP.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00898. 2A0119. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q547K2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTFDQALRK AGEFGRFQRR VFLLLCLTGV TFAFLFVGVV FLGSQPDYYW
60 70 80 90 100
CRGPRATALA ERCAWSPEEE WNLTTPELHV PAERRGQGHC HRYLLEATNT
110 120 130 140 150
SSELSCDPLT AFPNRSAPLV SCSGDWRYVE THSTIVSQFD LVCSNAWMLD
160 170 180 190 200
LTQAILNLGF LAGAFTLGYA ADRYGRLIIY LISCFGVGIT GVVVAFAPNF
210 220 230 240 250
SVFVIFRFLQ GVFGKGAWMT CFVIVTEIVG SKQRRIVGIV IQMFFTLGII
260 270 280 290 300
ILPGIAYFTP SWQGIQLAIS LPSFLFLLYY WVVPESPRWL ITRKQGEKAL
310 320 330 340 350
QILRRVAKCN GKHLSSNYSE ITVTDEEVSN PSCLDLVRTP QMRKCTLILM
360 370 380 390 400
FAWFTSAVVY QGLVMRLGLI GGNLYIDFFI SGLVELPGAL LILLTIERLG
410 420 430 440 450
RRLPFAASNI VAGVSCLVTA FLPEGIPWLR TTVATLGRLG ITMAFEIVYL
460 470 480 490 500
VNSELYPTTL RNFGVSLCSG LCDFGGIIAP FLLFRLAAIW LELPLIIFGI
510 520 530 540 550
LASVCGGLVM LLPETKGIAL PETVEDVEKL GSSQLHQCGR KKKTQVSTSD

V
Length:551
Mass (Da):61,053
Last modified:May 24, 2005 - v1
Checksum:iC4D66AAC2EFCFBDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC137661 mRNA. Translation: AAI37662.1.
BC137662 mRNA. Translation: AAI37663.1.
AF481053 Genomic DNA. Translation: AAM22155.1.
AK143988 mRNA. Translation: BAE25648.1.
CH466619 Genomic DNA. Translation: EDL02059.1.
RefSeqiNP_035525.1. NM_011395.2.
UniGeneiMm.99252.

Genome annotation databases

GeneIDi20519.
KEGGimmu:20519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC137661 mRNA. Translation: AAI37662.1.
BC137662 mRNA. Translation: AAI37663.1.
AF481053 Genomic DNA. Translation: AAM22155.1.
AK143988 mRNA. Translation: BAE25648.1.
CH466619 Genomic DNA. Translation: EDL02059.1.
RefSeqiNP_035525.1. NM_011395.2.
UniGeneiMm.99252.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000024595.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20519.
KEGGimmu:20519.

Organism-specific databases

CTDi6581.
MGIiMGI:1333817. Slc22a3.

Phylogenomic databases

eggNOGiENOG410IRIE. Eukaryota.
ENOG410XSRI. LUCA.
HOVERGENiHBG061545.
KOiK08200.
OMAiCQRYLLE.
OrthoDBiEOG091G05AC.

Miscellaneous databases

ChiTaRSiSlc22a3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000023828.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR004749. Orgcat_transp/SVOP.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00898. 2A0119. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ547K2_MOUSE
AccessioniPrimary (citable) accession number: Q547K2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.