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Protein
Submitted name:

E2F transcription factor 1, isoform CRA_a

Gene

E2f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
E2F transcription factor 1, isoform CRA_aImported
Submitted name:
E2F1Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:E2f1Imported
ORF Names:mCG_3689Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:101941. E2f1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000027490.
ExpressionAtlasiQ547J6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099434.

Structurei

3D structure databases

SMRiQ547J6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini122 – 187E2F_TDPInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the E2F/DP family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2577. Eukaryota.
ENOG410XNYI. LUCA.
HOVERGENiHBG002227.
KOiK17454.
OMAiHVREDFS.
OrthoDBiEOG091G087U.

Family and domain databases

CDDicd14660. E2F_DD. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR015633. E2F.
IPR032198. E2F_CC-MB.
IPR003316. E2F_WHTH_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR12081. PTHR12081. 1 hit.
PfamiView protein in Pfam
PF16421. E2F_CC-MB. 1 hit.
PF02319. E2F_TDP. 1 hit.
SMARTiView protein in SMART
SM01372. E2F_TDP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Complete.

Q547J6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAPAGGQH APALEALLGA GALRLLDSSQ IVIISTAPDV GAPQLPAAPP
60 70 80 90 100
TGPRDSDVLL FATPQAPRPA PSAPRPALGR PPVKRRLDLE TDHQYLAGSS
110 120 130 140 150
GPFRGRGRHP GKGVKSPGEK SRYETSLNLT TKRFLELLSR SADGVVDLNW
160 170 180 190 200
AAEVLKVQKR RIYDITNVLE GIQLIAKKSK NHIQWLGSHT MVGIGKRLEG
210 220 230 240 250
LTQDLQQLQE SEQQLDHLMH ICTTQLQLLS EDSDTQRLAY VTCQDLRSIA
260 270 280 290 300
DPAEQMVIVI KAPPETQLQA VDSSETFQIS LKSKQGPIDV FLCPEESADG
310 320 330 340 350
ISPGKTSCQE TSSGEDRTAD SGPAGPPPSP PSTSPALDPS QSLLGLEQEA
360 370 380 390 400
VLPRMGHLRV PMEEDQLSPL VAADSLLEHV KEDFSGLLPG EFISLSPPHE
410 420 430
ALDYHFGLEE GEGIRDLFDC DFGDLTPLDF
Length:430
Mass (Da):46,323
Last modified:May 24, 2005 - v1
Checksum:iC5DF18AD3B4DFEFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF483514 mRNA. Translation: AAL90788.1.
AF483515 mRNA. Translation: AAL90789.1.
AK153968 mRNA. Translation: BAE32285.1.
CH466551 Genomic DNA. Translation: EDL06086.1.
RefSeqiNP_031917.1. NM_007891.5.
UniGeneiMm.18036.
Mm.441323.

Genome annotation databases

GeneIDi13555.
KEGGimmu:13555.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF483514 mRNA. Translation: AAL90788.1.
AF483515 mRNA. Translation: AAL90789.1.
AK153968 mRNA. Translation: BAE32285.1.
CH466551 Genomic DNA. Translation: EDL06086.1.
RefSeqiNP_031917.1. NM_007891.5.
UniGeneiMm.18036.
Mm.441323.

3D structure databases

SMRiQ547J6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099434.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13555.
KEGGimmu:13555.

Organism-specific databases

CTDi1869.
MGIiMGI:101941. E2f1.

Phylogenomic databases

eggNOGiKOG2577. Eukaryota.
ENOG410XNYI. LUCA.
HOVERGENiHBG002227.
KOiK17454.
OMAiHVREDFS.
OrthoDBiEOG091G087U.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027490.
ExpressionAtlasiQ547J6. baseline and differential.

Family and domain databases

CDDicd14660. E2F_DD. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR015633. E2F.
IPR032198. E2F_CC-MB.
IPR003316. E2F_WHTH_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR12081. PTHR12081. 1 hit.
PfamiView protein in Pfam
PF16421. E2F_CC-MB. 1 hit.
PF02319. E2F_TDP. 1 hit.
SMARTiView protein in SMART
SM01372. E2F_TDP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ547J6_MOUSE
AccessioniPrimary (citable) accession number: Q547J6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 15, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.