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Protein

Protein E6

Gene

E6

Organism
Human papillomavirus type 16
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a major role in the induction and maintenance of cellular transformation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorUniRule annotationSAAS annotation, DNA-bindingUniRule annotationSAAS annotation
Biological processHost-virus interaction, Inhibition of host innate immune response by virusSAAS annotation, Modulation of host cell apoptosis by virusSAAS annotation, Transcription, Transcription regulationUniRule annotationSAAS annotation, Viral immunoevasion
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Protein E6UniRule annotationSAAS annotation
Gene namesi
Name:E6Imported
OrganismiHuman papillomavirus type 16Imported
Taxonomic identifieri333760 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePapillomaviridaeAlphapapillomavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cytoplasm UniRule annotation
  • Host nucleus UniRule annotation
  • Host nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasmSAAS annotation, Host nucleusUniRule annotationSAAS annotation

Expressioni

Keywords - Developmental stagei

Early proteinUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the papillomaviridae E6 protein family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

KOiK21807.

Family and domain databases

InterProiView protein in InterPro
IPR001334. E6.
PfamiView protein in Pfam
PF00518. E6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q547J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQKRTAMFQ DPQERPRKLP QLCTELQTTI HDIILECVYC KQQLLRREVY
60 70 80 90 100
DFAFRDLCIV YRDGNPYAVC DKCLKFYSKI SEYRHYCYSL YGTTLEQQYN
110 120 130 140 150
KPLCDLLIRC INCQKPLCPE EKQRHLDKKQ RFHNIRGRWT GRCMSCCRSS

RTRRETQL
Length:158
Mass (Da):19,187
Last modified:May 24, 2005 - v1
Checksum:i01FEF5ADCFDB37EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF486310 Genomic DNA. Translation: AAL96615.1.
AF486311 Genomic DNA. Translation: AAL96616.1.
AF486312 Genomic DNA. Translation: AAL96617.1.
AF486313 Genomic DNA. Translation: AAL96618.1.
AF486317 Genomic DNA. Translation: AAL96622.1.
AF486320 Genomic DNA. Translation: AAL96625.1.
AF486321 Genomic DNA. Translation: AAL96626.1.
AY098919 Genomic DNA. Translation: AAM29167.1.
EF422095 Genomic DNA. Translation: ABR08416.1.
EF422096 Genomic DNA. Translation: ABR08417.1.
EF422097 Genomic DNA. Translation: ABR08418.1.
EF422098 Genomic DNA. Translation: ABR08419.1.
EF422104 Genomic DNA. Translation: ABR08425.1.
EF422106 Genomic DNA. Translation: ABR08427.1.
EF422107 Genomic DNA. Translation: ABR08428.1.
EF422108 Genomic DNA. Translation: ABR08429.1.
EU880247 Genomic DNA. Translation: ACK57856.1.
EU880248 Genomic DNA. Translation: ACK57857.1.
EU880249 Genomic DNA. Translation: ACK57858.1.
EU880250 Genomic DNA. Translation: ACK57859.1.
EU880251 Genomic DNA. Translation: ACK57860.1.
EU880252 Genomic DNA. Translation: ACK57861.1.
EU880254 Genomic DNA. Translation: ACK57862.1.
EU880257 Genomic DNA. Translation: ACK57864.1.
EU880258 Genomic DNA. Translation: ACK57865.1.
EU880259 Genomic DNA. Translation: ACK57866.1.
EU880260 Genomic DNA. Translation: ACK57867.1.
EU880262 Genomic DNA. Translation: ACK57868.1.
EU880263 Genomic DNA. Translation: ACK57869.1.
EU880265 Genomic DNA. Translation: ACK57871.1.
EU880266 Genomic DNA. Translation: ACK57872.1.
EU880267 Genomic DNA. Translation: ACK57873.1.
EU880268 Genomic DNA. Translation: ACK57874.1.
EU880269 Genomic DNA. Translation: ACK57875.1.
EU880270 Genomic DNA. Translation: ACK57876.1.
EU880271 Genomic DNA. Translation: ACK57877.1.
EU880272 Genomic DNA. Translation: ACK57878.1.
HM211089 Genomic DNA. Translation: ADY75575.1.
JN381047 Genomic DNA. Translation: AEV66127.1.
JN381057 Genomic DNA. Translation: AEV66137.1.
JN381061 Genomic DNA. Translation: AEV66141.1.
JX412120 Genomic DNA. Translation: AFS64234.1.
KC736930 Genomic DNA. Translation: AGK72246.1.
KC904798 Genomic DNA. Translation: AGS42242.1.
KC904799 Genomic DNA. Translation: AGS42243.1.
KC904800 Genomic DNA. Translation: AGS42244.1.
KC904801 Genomic DNA. Translation: AGS42245.1.
KC904802 Genomic DNA. Translation: AGS42246.1.
KC904824 Genomic DNA. Translation: AGS42268.1.
KC904911 Genomic DNA. Translation: AGS42355.1.
KM058575 Genomic DNA. Translation: AIQ82755.1.
KM058577 Genomic DNA. Translation: AIQ82757.1.
KM058580 Genomic DNA. Translation: AIQ82760.1.
KM058582 Genomic DNA. Translation: AIQ82762.1.
KM058585 Genomic DNA. Translation: AIQ82765.1.
KM058588 Genomic DNA. Translation: AIQ82768.1.
KM058589 Genomic DNA. Translation: AIQ82769.1.
KM058592 Genomic DNA. Translation: AIQ82772.1.
KM058598 Genomic DNA. Translation: AIQ82778.1.
KM058601 Genomic DNA. Translation: AIQ82781.1.
KM058604 Genomic DNA. Translation: AIQ82784.1.
KP019227 Genomic DNA. Translation: AJP00105.1.
KP019235 Genomic DNA. Translation: AJP00113.1.
KP019247 Genomic DNA. Translation: AJP00125.1.
KP160934 Genomic DNA. Translation: AJW82136.1.
KP160945 Genomic DNA. Translation: AJW82147.1.
KP160956 Genomic DNA. Translation: AJW82158.1.
KP160960 Genomic DNA. Translation: AJW82162.1.
KT959527 Genomic DNA. Translation: ALN66895.1.
KT959538 Genomic DNA. Translation: ALN66906.1.
KT959540 Genomic DNA. Translation: ALN66908.1.
KT959548 Genomic DNA. Translation: ALN66916.1.
KT959551 Genomic DNA. Translation: ALN66919.1.
KT959554 Genomic DNA. Translation: ALN66922.1.
KT959556 Genomic DNA. Translation: ALN66924.1.
KT959562 Genomic DNA. Translation: ALN66930.1.
KP965019 Genomic DNA. Translation: ALU65714.1.
KP965022 Genomic DNA. Translation: ALU65717.1.
KP965023 Genomic DNA. Translation: ALU65718.1.
KP965024 Genomic DNA. Translation: ALU65719.1.
KP965026 Genomic DNA. Translation: ALU65721.1.
KP965029 Genomic DNA. Translation: ALU65724.1.
KP965030 Genomic DNA. Translation: ALU65725.1.
KP965038 Genomic DNA. Translation: ALU65733.1.
KP965039 Genomic DNA. Translation: ALU65734.1.
KP965042 Genomic DNA. Translation: ALU65737.1.
KP965043 Genomic DNA. Translation: ALU65738.1.
KP965044 Genomic DNA. Translation: ALU65739.1.
KP965046 Genomic DNA. Translation: ALU65741.1.
KP965049 Genomic DNA. Translation: ALU65744.1.
KP965056 Genomic DNA. Translation: ALU65751.1.
KP965059 Genomic DNA. Translation: ALU65754.1.
KP965061 Genomic DNA. Translation: ALU65756.1.
KP965062 Genomic DNA. Translation: ALU65757.1.
KP965063 Genomic DNA. Translation: ALU65758.1.
KP965065 Genomic DNA. Translation: ALU65760.1.
KP965068 Genomic DNA. Translation: ALU65763.1.
KP965069 Genomic DNA. Translation: ALU65764.1.
KP965073 Genomic DNA. Translation: ALU65768.1.
KP965078 Genomic DNA. Translation: ALU65773.1.
KP965084 Genomic DNA. Translation: ALU65779.1.
KP965093 Genomic DNA. Translation: ALU65788.1.
KP965099 Genomic DNA. Translation: ALU65794.1.
KP965100 Genomic DNA. Translation: ALU65795.1.
KP965101 Genomic DNA. Translation: ALU65796.1.
KP965103 Genomic DNA. Translation: ALU65798.1.
KP965106 Genomic DNA. Translation: ALU65801.1.
KP965108 Genomic DNA. Translation: ALU65803.1.
KP965109 Genomic DNA. Translation: ALU65804.1.
KP965110 Genomic DNA. Translation: ALU65805.1.
KP965111 Genomic DNA. Translation: ALU65806.1.
KP965113 Genomic DNA. Translation: ALU65808.1.
KP965114 Genomic DNA. Translation: ALU65809.1.
KP965116 Genomic DNA. Translation: ALU65811.1.
KP965120 Genomic DNA. Translation: ALU65815.1.
KP965124 Genomic DNA. Translation: ALU65819.1.
KP965125 Genomic DNA. Translation: ALU65820.1.
KP965128 Genomic DNA. Translation: ALU65823.1.
KP965132 Genomic DNA. Translation: ALU65827.1.
KP965133 Genomic DNA. Translation: ALU65828.1.
KP965134 Genomic DNA. Translation: ALU65829.1.
KP965135 Genomic DNA. Translation: ALU65830.1.
KP965136 Genomic DNA. Translation: ALU65831.1.
KP965137 Genomic DNA. Translation: ALU65832.1.
KP965139 Genomic DNA. Translation: ALU65834.1.
KP965140 Genomic DNA. Translation: ALU65835.1.
KP965141 Genomic DNA. Translation: ALU65836.1.
KU951196 Genomic DNA. Translation: ANY26498.1.
KU951208 Genomic DNA. Translation: ANY26522.1.
KU951209 Genomic DNA. Translation: ANY26524.1.
KU951211 Genomic DNA. Translation: ANY26528.1.
KU951212 Genomic DNA. Translation: ANY26530.1.
KU951216 Genomic DNA. Translation: ANY26538.1.
KU951219 Genomic DNA. Translation: ANY26544.1.
KU951225 Genomic DNA. Translation: ANY26555.1.
KU951232 Genomic DNA. Translation: ANY26569.1.
KU951233 Genomic DNA. Translation: ANY26571.1.
KU951238 Genomic DNA. Translation: ANY26581.1.
KU951239 Genomic DNA. Translation: ANY26583.1.
KY549156 Genomic DNA. Translation: ASJ77450.1.
KY549158 Genomic DNA. Translation: ASJ77466.1.
KY549159 Genomic DNA. Translation: ASJ77474.1.
KY549163 Genomic DNA. Translation: ASJ77506.1.
KY549165 Genomic DNA. Translation: ASJ77522.1.
KY549168 Genomic DNA. Translation: ASJ77546.1.
KY549169 Genomic DNA. Translation: ASJ77554.1.
KY549172 Genomic DNA. Translation: ASJ77578.1.
KY549173 Genomic DNA. Translation: ASJ77586.1.
KY549174 Genomic DNA. Translation: ASJ77594.1.
KY549176 Genomic DNA. Translation: ASJ77610.1.
KY549177 Genomic DNA. Translation: ASJ77618.1.
KY549178 Genomic DNA. Translation: ASJ77626.1.
KY549179 Genomic DNA. Translation: ASJ77634.1.
KY549180 Genomic DNA. Translation: ASJ77642.1.
KY549181 Genomic DNA. Translation: ASJ77650.1.
KY549182 Genomic DNA. Translation: ASJ77658.1.
KY549183 Genomic DNA. Translation: ASJ77666.1.
KY549189 Genomic DNA. Translation: ASJ77714.1.
KY549197 Genomic DNA. Translation: ASJ77778.1.
KY549201 Genomic DNA. Translation: ASJ77810.1.
KY549202 Genomic DNA. Translation: ASJ77818.1.
KY549204 Genomic DNA. Translation: ASJ77834.1.
KY549213 Genomic DNA. Translation: ASJ77906.1.
KY549215 Genomic DNA. Translation: ASJ77922.1.
KY549220 Genomic DNA. Translation: ASJ77962.1.
KY549226 Genomic DNA. Translation: ASJ78010.1.
KY549227 Genomic DNA. Translation: ASJ78018.1.
KY549234 Genomic DNA. Translation: ASJ78074.1.
KY549235 Genomic DNA. Translation: ASJ78082.1.
KY549236 Genomic DNA. Translation: ASJ78090.1.
KY549239 Genomic DNA. Translation: ASJ78114.1.
KY549240 Genomic DNA. Translation: ASJ78122.1.
KY549255 Genomic DNA. Translation: ASJ78242.1.
KY549256 Genomic DNA. Translation: ASJ78250.1.
KY549261 Genomic DNA. Translation: ASJ78290.1.
KY549265 Genomic DNA. Translation: ASJ78322.1.
KY549266 Genomic DNA. Translation: ASJ78330.1.
KY549267 Genomic DNA. Translation: ASJ78338.1.
KY549268 Genomic DNA. Translation: ASJ78346.1.
KY549279 Genomic DNA. Translation: ASJ78434.1.
KY549285 Genomic DNA. Translation: ASJ78482.1.
KY549286 Genomic DNA. Translation: ASJ78490.1.
KY549289 Genomic DNA. Translation: ASJ78514.1.
KY549290 Genomic DNA. Translation: ASJ78522.1.
KY549291 Genomic DNA. Translation: ASJ78530.1.
KY549292 Genomic DNA. Translation: ASJ78538.1.
KY549293 Genomic DNA. Translation: ASJ78546.1.
KY549296 Genomic DNA. Translation: ASJ78570.1.
KY549297 Genomic DNA. Translation: ASJ78578.1.
KY549300 Genomic DNA. Translation: ASJ78602.1.
KY549301 Genomic DNA. Translation: ASJ78610.1.
KY549302 Genomic DNA. Translation: ASJ78618.1.
KY549303 Genomic DNA. Translation: ASJ78626.1.
KY549304 Genomic DNA. Translation: ASJ78634.1.
KY549314 Genomic DNA. Translation: ASJ78714.1.
KY549318 Genomic DNA. Translation: ASJ78746.1.
KY549319 Genomic DNA. Translation: ASJ78754.1.
MF066746 Genomic DNA. Translation: ASV48631.1.
MF066756 Genomic DNA. Translation: ASV48641.1.
MF066761 Genomic DNA. Translation: ASV48646.1.
MF066774 Genomic DNA. Translation: ASV48659.1.
AB663688 Genomic DNA. Translation: BAN15903.1.
AB663690 Genomic DNA. Translation: BAN15905.1.
AB663691 Genomic DNA. Translation: BAN15906.1.
AB663692 Genomic DNA. Translation: BAN15907.1.
AB663695 Genomic DNA. Translation: BAN15910.1.
AB663696 Genomic DNA. Translation: BAN15911.1.
AB663700 Genomic DNA. Translation: BAN15915.1.
AB663706 Genomic DNA. Translation: BAN15921.1.
AB663718 Genomic DNA. Translation: BAN15933.1.
AB663724 Genomic DNA. Translation: BAN15939.1.
AB663727 Genomic DNA. Translation: BAN15942.1.
AB663730 Genomic DNA. Translation: BAN15945.1.
AB663734 Genomic DNA. Translation: BAN15949.1.
AB663735 Genomic DNA. Translation: BAN15950.1.
AB663737 Genomic DNA. Translation: BAN15952.1.
AB663739 Genomic DNA. Translation: BAN15954.1.
AB663741 Genomic DNA. Translation: BAN15956.1.
LC027929 Genomic DNA. Translation: BAQ53892.1.
LC027224 Genomic DNA. Translation: BAQ55596.1.
RefSeqiNP_041325.1. NC_001526.4.

Genome annotation databases

GeneIDi1489078.
KEGGivg:1489078.

Similar proteinsi

Entry informationi

Entry nameiQ547J2_HPV16
AccessioniPrimary (citable) accession number: Q547J2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)