Unreviewed, UniProtKB/TrEMBL Q546Y9 (Q546Y9_HUMAN)

Names and origin

Protein names

Submitted name:
    AID EMBL AAM95413.1
Submitted name:
    Activation-induced cytidine deaminase EMBL EAW88615.1

Gene names

Name:	AID EMBL AAM95413.1
Synonyms:	AICDA EMBL EAW88615.1
ORF Names:	hCG_25220 EMBL EAW88615.1

Organism

Homo sapiens (Human) EMBL AAM95413.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	198 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	isotype switching Inferred from electronic annotation. Source: Compara
Molecular function	cytidine deaminase activity Inferred from electronic annotation. Source: Compara hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	198	1	EMBL AAM95413.1

Sequences

	Sequence		Length	Mass (Da)
	Q546Y9-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 3C27BB143DB184A9	FASTA	198	23,954
	10 20 30 40 50 60 MDSLLMNRRK FLYQFKNVRW AKGRRETYLC YVVKRRDSAT SFSLDFGYLR NKNGCHVELL 70 80 90 100 110 120 FLRYISDWDL DPGRCYRVTW FTSWSPCYDC ARHVADFLRG NPNLSLRIFT ARLYFCEDRK 130 140 150 160 170 180 AEPEGLRRLH RAGVQIAIMT FKDYFYCWNT FVENHERTFK AWEGLHENSV RLSRQLRRIL 190 LPLYEVDDLR DAFRTLGL

References

[1]	"Somatic hypermutation of the AID transgene in B and non-B cells." Martin A., Scharff M.D. Proc. Natl. Acad. Sci. U.S.A. 99:12304-12308(2002) [PubMed: 12202747] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF529823 mRNA. Translation: AAM95410.1. AF529826 mRNA. Translation: AAM95413.1. CH471116 Genomic DNA. Translation: EAW88615.1.
IPI	IPI00010186.
RefSeq	NP_065712.1.
UniGene	Hs.149342
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q546Y9.
Genome annotation databases
Ensembl	ENSG00000111732. Homo sapiens. [Contig view]
GeneID	57379.
KEGG	hsa:57379.
Organism-specific databases
HGNC	HGNC:13203. AICDA.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q546Y9.
OMA	Q546Y9. CWNTFVE.
Gene expression databases
ArrayExpress	Q546Y9.
Bgee	Q546Y9.
Family and domain databases
InterPro	IPR016192. APOBEC/CMP_deaminase_Zn-bd. IPR007904. APOBEC_C. IPR013158. APOBEC_N. [Graphical view]
Pfam	PF05240. APOBEC_C. 1 hit. PF08210. APOBEC_N. 1 hit. [Graphical view]
PROSITE	PS00903. CYT_DCMP_DEAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	63478.

Entry information

Entry name

Q546Y9_HUMAN

Accession

Primary (citable) accession number: Q546Y9

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)