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Protein
Submitted name:

RAN binding protein 17, isoform CRA_b

Gene

RANBP17

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RAN binding protein 17, isoform CRA_bImported
Gene namesi
Name:RANBP17Imported
ORF Names:hCG_1979306Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34208.

Expressioni

Gene expression databases

ExpressionAtlasiQ546R4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000427975.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 9566Importin N-terminalInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1410. Eukaryota.
ENOG410XRPR. LUCA.
HOGENOMiHOG000018865.
HOVERGENiHBG018869.
OMAiQEVLAQC.
PhylomeDBiQ546R4.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF03810. IBN_N. 1 hit.
[Graphical view]
SMARTiSM00913. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.

Sequencei

Sequence statusi: Complete.

Q546R4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALHFQSLAE LEVLCTHLYI GTDLTQRIEA EKALLELIDS PECLSKCQLL
60 70 80 90 100
LEQGTTSYAQ LLAATCLSKL VSRVSPLPVE QRMDIRNYIL NYVASQPKLA
110 120 130 140 150
PFVIQALIQV IAKITKLGWF EVQKDQFVFR EIIADVKKFL QGTVEHCIIG
160 170 180 190 200
VIILSELTQE MNLVDYSRPS AKHRKIATSF RDTSLKDVLV LACSLLKEVF
210 220 230 240 250
AKPLNLQDQC QQNLVMQVLK LVLNCLNFDF IGSSADESAD DLCTVQIPTT
260 270 280 290 300
WRTIFLEPET LDLFFNLYHS LPPLLSQLAL SCLVQFASTR RSLFNSPERA
310 320 330 340 350
KYLGNLIKGV KRILENPQGL SDPGNYHEFC RFLARLKTNY QLGELVMVKE
360 370 380 390 400
YPEVIRLIAN FTITSLQHWE FAPNSVHYLL TLWQRMVASV PFVKSTEPHL
410 420 430 440 450
LDTYAPEITK AFITSRLDSV AIVVRDHLDD PLDDTATVFQ QLEQLCTVSR
460 470 480 490 500
CEYEKTCALL VQLFDQNAQN YQKLLHPYSG VTVDITIQEG RLAWLVYLVG
510 520 530 540 550
TVVGGRLTYT STDEHDAMDG ELSCRVFQLI SLMDTGLPRC CNEKIELAIL
560 570 580 590 600
WFLDQFRKTY VGDQLQRTSK VYARMSEVLG ITDDNHVLET FMTKIVTNLK
610 620 630 640 650
YWGRYEPVIS RTLQFLNDLS VGYILLKKLV KIDAVKFMLK NHTSEHFPFL
660 670 680 690 700
GISDNHSLSD FRCRTTFYTA LTRLLMVDLG EDEDEFENFM LPLTVAFETV
710 720 730 740 750
LQIFNNNFKQ EDVKRMLIGL ARDLRGIAFA LNTKTSYTML FDWMYPTYLP
760 770 780 790 800
LLQNAVERWY GEPTCTTPIL KLMAELMQNR SQRLNFDVSS PNGILLFREA
810 820 830 840 850
SKMVCTYGNQ ILSLGSLSKD QIYPMKLKGI SICYSALKSA LCGNYVSFGV
860 870 880 890 900
FKLYGDNHFD NVLQAFVKML LSVSHSDLLQ YRKLSQSYYP LLECLTQDHM
910 920 930 940 950
SFIINLEPPV LMYVLTSISE GLTTLDTVVS SSCCTSLDYI VTYLFKHIAK
960 970 980 990 1000
EGKKPLRCRE ATQAGQRLLH FMQQNPDVLQ QMMSVLMNTI VFEDCRNQWS
1010 1020 1030 1040 1050
VSRPLLGLIL LNEKYFSELR ASLINSQPLP KQEVLAQCFR NLMEGVEQNL
1060 1070 1080
SVKNRDRFTQ NLSVFRRDVA EALRSDGNTE PCSLDMMS
Length:1,088
Mass (Da):124,375
Last modified:May 24, 2005 - v1
Checksum:iA95D5599388EAEFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271459 mRNA. Translation: CAC81055.1.
CH471062 Genomic DNA. Translation: EAW61455.1.
RefSeqiNP_075048.1. NM_022897.4.
UniGeneiHs.410810.

Genome annotation databases

GeneIDi64901.
KEGGihsa:64901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271459 mRNA. Translation: CAC81055.1.
CH471062 Genomic DNA. Translation: EAW61455.1.
RefSeqiNP_075048.1. NM_022897.4.
UniGeneiHs.410810.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000427975.

Protocols and materials databases

DNASUi64901.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi64901.
KEGGihsa:64901.

Organism-specific databases

CTDi64901.
PharmGKBiPA34208.

Phylogenomic databases

eggNOGiKOG1410. Eukaryota.
ENOG410XRPR. LUCA.
HOGENOMiHOG000018865.
HOVERGENiHBG018869.
OMAiQEVLAQC.
PhylomeDBiQ546R4.

Miscellaneous databases

ChiTaRSiRANBP17. human.
GenomeRNAii64901.
NextBioi67049.

Gene expression databases

ExpressionAtlasiQ546R4. baseline and differential.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF03810. IBN_N. 1 hit.
[Graphical view]
SMARTiSM00913. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.
ProtoNetiSearch...

Publicationsi

  1. "Identification of a gene located at the chromosomal breakpoint t(5;14)(q33-q34;q11), a recurring chromosomal aberration in a subset of human acute leukemias."
    Hansen-Hagge T.E., Schaefer M., Kiyoi H., Bohlmann I., Koch P., Morris S., Bartram C.R., Janssen J.W.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  2. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ546R4_HUMAN
AccessioniPrimary (citable) accession number: Q546R4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 11, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.