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Protein
Submitted name:

Arylamine N-acetyltransferase 1

Gene

Nat1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • arylamine N-acetyltransferase activity Source: MGI

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Arylamine N-acetyltransferase 1Imported (EC:2.3.1.5Imported)
Submitted name:
N-acetyltransferase 1 (Arylamine N-acetyltransferase)Imported
Gene namesi
Name:Nat1Imported
ORF Names:mCG_5308Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97279. Nat1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ546L3. baseline and differential.
GenevestigatoriQ546L3.

Structurei

3D structure databases

ProteinModelPortaliQ546L3.
SMRiQ546L3. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arylamine N-acetyltransferase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000012054.
HOVERGENiHBG000165.
KOiK00622.
OMAiPATHTLM.
PhylomeDBiQ546L3.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.

Sequencei

Sequence statusi: Complete.

Q546L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIEAYFERI GYKNSVNKLD LATLTEVLQH QMRAVPFENL NMHCGEAMHL
60 70 80 90 100
DLQDIFDHIV RKKRGGWCLQ VNHLLYWALT KMGFETTMLG GYVYITPVSK
110 120 130 140 150
YSSEMVHLLV QVTISDRKYI VDSAYGGSYQ MWEPLELTSG KDQPQVPAIF
160 170 180 190 200
LLTEENGTWY LDQIRREQYV PNEEFVNSDL LEKNKYRKIY SFTLEPRVIE
210 220 230 240 250
DFEYVNSYLQ TSPASVFVST SFCSLQTSEG VHCLVGSTFT SRRFSYKDDV
260 270 280 290
DLVEFKYVNE EEIEDVLKTA FGISLERKFV PKHGELVFTI
Length:290
Mass (Da):33,713
Last modified:May 24, 2005 - v1
Checksum:i228C64130A2AD881
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119181 mRNA. Translation: AAI19182.1.
BC137747 mRNA. Translation: AAI37748.1.
AJ314651 Genomic DNA. Translation: CAC85410.1.
AJ314652 Genomic DNA. Translation: CAC85411.1.
AJ314653 Genomic DNA. Translation: CAC85412.1.
AJ314650 Genomic DNA. Translation: CAC85426.1.
CH466569 Genomic DNA. Translation: EDL28704.1.
RefSeqiNP_032699.1. NM_008673.1.
UniGeneiMm.14125.

Genome annotation databases

GeneIDi17960.
KEGGimmu:17960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119181 mRNA. Translation: AAI19182.1.
BC137747 mRNA. Translation: AAI37748.1.
AJ314651 Genomic DNA. Translation: CAC85410.1.
AJ314652 Genomic DNA. Translation: CAC85411.1.
AJ314653 Genomic DNA. Translation: CAC85412.1.
AJ314650 Genomic DNA. Translation: CAC85426.1.
CH466569 Genomic DNA. Translation: EDL28704.1.
RefSeqiNP_032699.1. NM_008673.1.
UniGeneiMm.14125.

3D structure databases

ProteinModelPortaliQ546L3.
SMRiQ546L3. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17960.
KEGGimmu:17960.

Organism-specific databases

CTDi9.
MGIiMGI:97279. Nat1.

Phylogenomic databases

GeneTreeiENSGT00390000012054.
HOVERGENiHBG000165.
KOiK00622.
OMAiPATHTLM.
PhylomeDBiQ546L3.

Miscellaneous databases

NextBioi292883.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiQ546L3. baseline and differential.
GenevestigatoriQ546L3.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice."
    Boukouvala S., Price N., Sim E.
    Pharmacogenetics 12:385-394(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129/OlaImported, CBAImported, POImported and TOImported.
  2. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ546L3_MOUSE
AccessioniPrimary (citable) accession number: Q546L3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.