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Q546L3

- Q546L3_MOUSE

UniProt

Q546L3 - Q546L3_MOUSE

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Protein
Submitted name:

Arylamine N-acetyltransferase 1

Gene

Nat1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. arylamine N-acetyltransferase activity Source: MGI

GO - Biological processi

  1. aging Source: Ensembl
  2. heart development Source: Ensembl
  3. liver development Source: Ensembl
  4. response to thyroxine Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Arylamine N-acetyltransferase 1Imported (EC:2.3.1.5Imported)
Submitted name:
N-acetyltransferase 1 (Arylamine N-acetyltransferase)Imported
Gene namesi
Name:Nat1Imported
ORF Names:mCG_5308Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97279. Nat1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ546L3.

Family & Domainsi

Sequence similaritiesi

Belongs to the arylamine N-acetyltransferase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000012054.
HOVERGENiHBG000165.
KOiK00622.
OMAiSKYSSEM.

Family and domain databases

InterProiIPR001447. Arylamine_N-AcTrfase.
[Graphical view]
PANTHERiPTHR11786. PTHR11786. 1 hit.
PfamiPF00797. Acetyltransf_2. 1 hit.
[Graphical view]
PRINTSiPR01543. ANATRNSFRASE.

Sequencei

Sequence statusi: Complete.

Q546L3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDIEAYFERI GYKNSVNKLD LATLTEVLQH QMRAVPFENL NMHCGEAMHL
60 70 80 90 100
DLQDIFDHIV RKKRGGWCLQ VNHLLYWALT KMGFETTMLG GYVYITPVSK
110 120 130 140 150
YSSEMVHLLV QVTISDRKYI VDSAYGGSYQ MWEPLELTSG KDQPQVPAIF
160 170 180 190 200
LLTEENGTWY LDQIRREQYV PNEEFVNSDL LEKNKYRKIY SFTLEPRVIE
210 220 230 240 250
DFEYVNSYLQ TSPASVFVST SFCSLQTSEG VHCLVGSTFT SRRFSYKDDV
260 270 280 290
DLVEFKYVNE EEIEDVLKTA FGISLERKFV PKHGELVFTI
Length:290
Mass (Da):33,713
Last modified:May 24, 2005 - v1
Checksum:i228C64130A2AD881
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119181 mRNA. Translation: AAI19182.1.
BC137747 mRNA. Translation: AAI37748.1.
AJ314651 Genomic DNA. Translation: CAC85410.1.
AJ314652 Genomic DNA. Translation: CAC85411.1.
AJ314653 Genomic DNA. Translation: CAC85412.1.
AJ314650 Genomic DNA. Translation: CAC85426.1.
CH466569 Genomic DNA. Translation: EDL28704.1.
RefSeqiNP_032699.1. NM_008673.1.
XP_006509654.1. XM_006509591.1.
UniGeneiMm.14125.

Genome annotation databases

GeneIDi17960.
KEGGimmu:17960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119181 mRNA. Translation: AAI19182.1 .
BC137747 mRNA. Translation: AAI37748.1 .
AJ314651 Genomic DNA. Translation: CAC85410.1 .
AJ314652 Genomic DNA. Translation: CAC85411.1 .
AJ314653 Genomic DNA. Translation: CAC85412.1 .
AJ314650 Genomic DNA. Translation: CAC85426.1 .
CH466569 Genomic DNA. Translation: EDL28704.1 .
RefSeqi NP_032699.1. NM_008673.1.
XP_006509654.1. XM_006509591.1.
UniGenei Mm.14125.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 17960.
KEGGi mmu:17960.

Organism-specific databases

CTDi 9.
MGIi MGI:97279. Nat1.

Phylogenomic databases

GeneTreei ENSGT00390000012054.
HOVERGENi HBG000165.
KOi K00622.
OMAi SKYSSEM.

Miscellaneous databases

NextBioi 292883.
SOURCEi Search...

Gene expression databases

Genevestigatori Q546L3.

Family and domain databases

InterProi IPR001447. Arylamine_N-AcTrfase.
[Graphical view ]
PANTHERi PTHR11786. PTHR11786. 1 hit.
Pfami PF00797. Acetyltransf_2. 1 hit.
[Graphical view ]
PRINTSi PR01543. ANATRNSFRASE.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice."
    Boukouvala S., Price N., Sim E.
    Pharmacogenetics 12:385-394(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129/OlaImported, CBAImported, POImported and TOImported.
  2. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ546L3_MOUSE
AccessioniPrimary (citable) accession number: Q546L3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)