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Protein
Submitted name:

Albumin 1

Gene

Alb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Albumin 1Imported
Submitted name:
Serum albuminImported
Gene namesi
Name:AlbImported
Synonyms:albImported, Alb1Imported
ORF Names:mCG_1705Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87991. Alb.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedPROSITE-ProRule annotation

Pathology & Biotechi

Protein family/group databases

Allergomei755. Mus m 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501097362419 – 608Sequence analysisAdd BLAST590

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 78PROSITE-ProRule annotation
Disulfide bondi77 ↔ 86UniRule annotation
Disulfide bondi99 ↔ 115UniRule annotation
Disulfide bondi114 ↔ 125UniRule annotation
Disulfide bondi148 ↔ 193UniRule annotation
Disulfide bondi192 ↔ 201UniRule annotation
Disulfide bondi224 ↔ 270UniRule annotation
Disulfide bondi269 ↔ 277UniRule annotation
Disulfide bondi289 ↔ 303UniRule annotation
Disulfide bondi302 ↔ 313UniRule annotation
Disulfide bondi340 ↔ 385UniRule annotation
Disulfide bondi384 ↔ 393UniRule annotation
Disulfide bondi416 ↔ 462UniRule annotation
Disulfide bondi461 ↔ 472UniRule annotation
Disulfide bondi461 ↔ 469PROSITE-ProRule annotation
Disulfide bondi485 ↔ 501UniRule annotation
Disulfide bondi500 ↔ 511UniRule annotation
Disulfide bondi538 ↔ 583UniRule annotation
Disulfide bondi582 ↔ 591UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000029368.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 211AlbuminInterPro annotationAdd BLAST193
Domaini212 – 403AlbuminInterPro annotationAdd BLAST192
Domaini404 – 601AlbuminInterPro annotationAdd BLAST198

Sequence similaritiesi

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
HOVERGENiHBG004207.
KOiK16141.
OMAiKTCVADE.
OrthoDBiEOG091G0F5F.

Family and domain databases

CDDicd00015. ALBUMIN. 3 hits.
InterProiView protein in InterPro
IPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
PANTHERiPTHR11385. PTHR11385. 1 hit.
PfamiView protein in Pfam
PF00273. Serum_albumin. 3 hits.
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00802. SERUMALBUMIN.
SMARTiView protein in SMART
SM00103. ALBUMIN. 3 hits.
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiView protein in PROSITE
PS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.

Sequencei

Sequence statusi: Complete.

Q546G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWVTFLLLL FVSGSAFSRG VFRREAHKSE IAHRYNDLGE QHFKGLVLIA
60 70 80 90 100
FSQYLQKCSY DEHAKLVQEV TDFAKTCVAD ESAANCDKSL HTLFGDKLCA
110 120 130 140 150
IPNLRENYGE LADCCTKQEP ERNECFLQHK DDNPSLPPFE RPEAEAMCTS
160 170 180 190 200
FKENPTTFMG HYLHEVARRH PYFYAPELLY YAEQYNEILT QCCAEADKES
210 220 230 240 250
CLTPKLDGVK EKALVSSVRQ RMKCSSMQKF GERAFKAWAV ARLSQTFPNA
260 270 280 290 300
DFAEITKLAT DLTKVNKECC HGDLLECADD RAELAKYMCE NQATISSKLQ
310 320 330 340 350
TCCDKPLLKK AHCLSEVEHD TMPADLPAIA ADFVEDQEVC KNYAEAKDVF
360 370 380 390 400
LGTFLYEYSR RHPDYSVSLL LRLAKKYEAT LEKCCAEANP PACYGTVLAE
410 420 430 440 450
FQPLVEEPKN LVKTNCDLYE KLGEYGFQNA ILVRYTQKAP QVSTPTLVEA
460 470 480 490 500
ARNLGRVGTK CCTLPEDQRL PCVEDYLSAI LNRVCLLHEK TPVSEHVTKC
510 520 530 540 550
CSGSLVERRP CFSALTVDET YVPKEFKAET FTFHSDICTL PEKEKQIKKQ
560 570 580 590 600
TALAELVKHK PKATAEQLKT VMDDFAQFLD TCCKAADKDT CFSTEGPNLV

TRCKDALA
Length:608
Mass (Da):68,693
Last modified:May 24, 2005 - v1
Checksum:i292F7C7EED3A61B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131891 mRNA. Translation: BAE20854.1.
AJ457860 mRNA. Translation: CAD29888.1.
CH466617 Genomic DNA. Translation: EDL05322.1.
RefSeqiNP_033784.2. NM_009654.4.
UniGeneiMm.16773.

Genome annotation databases

GeneIDi11657.
KEGGimmu:11657.

Similar proteinsi

Entry informationi

Entry nameiQ546G4_MOUSE
AccessioniPrimary (citable) accession number: Q546G4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation