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Protein
Submitted name:

Albumin 1

Gene

Alb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chaperone binding Source: MGI
  2. DNA binding Source: MGI
  3. drug binding Source: MGI
  4. fatty acid binding Source: MGI
  5. oxygen binding Source: Ensembl
  6. pyridoxal phosphate binding Source: MGI
  7. toxic substance binding Source: MGI
  8. zinc ion binding Source: Ensembl

GO - Biological processi

  1. cellular response to starvation Source: MGI
  2. hemolysis by symbiont of host erythrocytes Source: MGI
  3. maintenance of mitochondrion location Source: MGI
  4. negative regulation of apoptotic process Source: MGI
  5. positive regulation of circadian sleep/wake cycle, non-REM sleep Source: Ensembl
  6. response to mercury ion Source: Ensembl
  7. response to nutrient Source: Ensembl
  8. response to organic substance Source: Ensembl
  9. response to platinum ion Source: Ensembl
  10. retina homeostasis Source: Ensembl
  11. transport Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Albumin 1Imported
Submitted name:
Serum albuminImported
Gene namesi
Name:AlbImported
Synonyms:albImported, Alb1Imported
ORF Names:mCG_1705Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87991. Alb.

Subcellular locationi

GO - Cellular componenti

  1. basement membrane Source: Ensembl
  2. blood microparticle Source: MGI
  3. cytoplasm Source: MGI
  4. extracellular region Source: MGI
  5. extracellular space Source: MGI
  6. extracellular vesicular exosome Source: MGI
  7. nucleus Source: MGI
  8. protein complex Source: MGI
Complete GO annotation...

Pathology & Biotechi

Protein family/group databases

Allergomei755. Mus m 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 PotentialImportedAdd
BLAST
Chaini19 – 608590 PotentialImportedPRO_5000068495Add
BLAST
Chaini25 – 608584serum albuminImportedPRO_5000068496Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ546G4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031314.

Structurei

3D structure databases

ProteinModelPortaliQ546G4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

GeneTreeiENSGT00390000000113.
HOVERGENiHBG004207.
KOiK16141.
OMAiNRLCVLH.

Family and domain databases

InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q546G4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKWVTFLLLL FVSGSAFSRG VFRREAHKSE IAHRYNDLGE QHFKGLVLIA
60 70 80 90 100
FSQYLQKCSY DEHAKLVQEV TDFAKTCVAD ESAANCDKSL HTLFGDKLCA
110 120 130 140 150
IPNLRENYGE LADCCTKQEP ERNECFLQHK DDNPSLPPFE RPEAEAMCTS
160 170 180 190 200
FKENPTTFMG HYLHEVARRH PYFYAPELLY YAEQYNEILT QCCAEADKES
210 220 230 240 250
CLTPKLDGVK EKALVSSVRQ RMKCSSMQKF GERAFKAWAV ARLSQTFPNA
260 270 280 290 300
DFAEITKLAT DLTKVNKECC HGDLLECADD RAELAKYMCE NQATISSKLQ
310 320 330 340 350
TCCDKPLLKK AHCLSEVEHD TMPADLPAIA ADFVEDQEVC KNYAEAKDVF
360 370 380 390 400
LGTFLYEYSR RHPDYSVSLL LRLAKKYEAT LEKCCAEANP PACYGTVLAE
410 420 430 440 450
FQPLVEEPKN LVKTNCDLYE KLGEYGFQNA ILVRYTQKAP QVSTPTLVEA
460 470 480 490 500
ARNLGRVGTK CCTLPEDQRL PCVEDYLSAI LNRVCLLHEK TPVSEHVTKC
510 520 530 540 550
CSGSLVERRP CFSALTVDET YVPKEFKAET FTFHSDICTL PEKEKQIKKQ
560 570 580 590 600
TALAELVKHK PKATAEQLKT VMDDFAQFLD TCCKAADKDT CFSTEGPNLV

TRCKDALA
Length:608
Mass (Da):68,693
Last modified:May 24, 2005 - v1
Checksum:i292F7C7EED3A61B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131891 mRNA. Translation: BAE20854.1.
AJ457860 mRNA. Translation: CAD29888.1.
CH466617 Genomic DNA. Translation: EDL05322.1.
RefSeqiNP_033784.2. NM_009654.3.
UniGeneiMm.16773.

Genome annotation databases

GeneIDi11657.
KEGGimmu:11657.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131891 mRNA. Translation: BAE20854.1.
AJ457860 mRNA. Translation: CAD29888.1.
CH466617 Genomic DNA. Translation: EDL05322.1.
RefSeqiNP_033784.2. NM_009654.3.
UniGeneiMm.16773.

3D structure databases

ProteinModelPortaliQ546G4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031314.

Protein family/group databases

Allergomei755. Mus m 4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11657.
KEGGimmu:11657.

Organism-specific databases

CTDi213.
MGIiMGI:87991. Alb.

Phylogenomic databases

GeneTreeiENSGT00390000000113.
HOVERGENiHBG004207.
KOiK16141.
OMAiNRLCVLH.

Miscellaneous databases

ChiTaRSiAlb. mouse.
NextBioi279275.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ546G4.

Family and domain databases

InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 3 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. "Mus musculus mRNA coding for serum albumin."
    Le Pogam C., Hilger C., Hentges F.
    Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Balb/cImported.
    Tissue: LiverImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  9. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: StomachImported.
  11. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ546G4_MOUSE
AccessioniPrimary (citable) accession number: Q546G4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: February 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.