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Q546G4

- Q546G4_MOUSE

UniProt

Q546G4 - Q546G4_MOUSE

Protein
Submitted name:

Albumin 1

Gene

Alb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. fatty acid binding Source: Ensembl
    3. oxygen binding Source: Ensembl
    4. pyridoxal phosphate binding Source: Ensembl
    5. toxic substance binding Source: Ensembl
    6. zinc ion binding Source: Ensembl

    GO - Biological processi

    1. cellular response to starvation Source: Ensembl
    2. hemolysis by symbiont of host erythrocytes Source: Ensembl
    3. maintenance of mitochondrion location Source: Ensembl
    4. negative regulation of apoptotic process Source: Ensembl
    5. positive regulation of circadian sleep/wake cycle, non-REM sleep Source: Ensembl
    6. response to mercury ion Source: Ensembl
    7. response to nutrient Source: Ensembl
    8. response to organic substance Source: Ensembl
    9. response to platinum ion Source: Ensembl
    10. transport Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Albumin 1Imported
    Submitted name:
    Serum albuminImported
    Gene namesi
    Name:AlbImported
    Synonyms:albImported, Alb1Imported
    ORF Names:mCG_1705Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:87991. Alb.

    Subcellular locationi

    GO - Cellular componenti

    1. basement membrane Source: Ensembl
    2. cytoplasm Source: MGI
    3. extracellular region Source: MGI
    4. extracellular space Source: MGI
    5. extracellular vesicular exosome Source: Ensembl
    6. protein complex Source: Ensembl

    Pathology & Biotechi

    Protein family/group databases

    Allergomei755. Mus m 4.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818 PotentialImportedAdd
    BLAST
    Chaini19 – 608590 PotentialImportedPRO_5000068495Add
    BLAST
    Chaini25 – 608584serum albuminImportedPRO_5000068496Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ546G4.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000031314.

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    GeneTreeiENSGT00390000000113.
    HOVERGENiHBG004207.
    InParanoidiQ546G4.
    KOiK16141.
    OMAiNCDKSLH.

    Family and domain databases

    InterProiIPR000264. ALB/AFP/VDB.
    IPR020858. Serum_albumin-like.
    IPR021177. Serum_albumin/AFP.
    IPR020857. Serum_albumin_CS.
    IPR014760. Serum_albumin_N.
    [Graphical view]
    PfamiPF00273. Serum_albumin. 3 hits.
    [Graphical view]
    PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
    PRINTSiPR00802. SERUMALBUMIN.
    SMARTiSM00103. ALBUMIN. 3 hits.
    [Graphical view]
    SUPFAMiSSF48552. SSF48552. 3 hits.
    PROSITEiPS00212. ALBUMIN_1. 3 hits.
    PS51438. ALBUMIN_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q546G4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKWVTFLLLL FVSGSAFSRG VFRREAHKSE IAHRYNDLGE QHFKGLVLIA    50
    FSQYLQKCSY DEHAKLVQEV TDFAKTCVAD ESAANCDKSL HTLFGDKLCA 100
    IPNLRENYGE LADCCTKQEP ERNECFLQHK DDNPSLPPFE RPEAEAMCTS 150
    FKENPTTFMG HYLHEVARRH PYFYAPELLY YAEQYNEILT QCCAEADKES 200
    CLTPKLDGVK EKALVSSVRQ RMKCSSMQKF GERAFKAWAV ARLSQTFPNA 250
    DFAEITKLAT DLTKVNKECC HGDLLECADD RAELAKYMCE NQATISSKLQ 300
    TCCDKPLLKK AHCLSEVEHD TMPADLPAIA ADFVEDQEVC KNYAEAKDVF 350
    LGTFLYEYSR RHPDYSVSLL LRLAKKYEAT LEKCCAEANP PACYGTVLAE 400
    FQPLVEEPKN LVKTNCDLYE KLGEYGFQNA ILVRYTQKAP QVSTPTLVEA 450
    ARNLGRVGTK CCTLPEDQRL PCVEDYLSAI LNRVCLLHEK TPVSEHVTKC 500
    CSGSLVERRP CFSALTVDET YVPKEFKAET FTFHSDICTL PEKEKQIKKQ 550
    TALAELVKHK PKATAEQLKT VMDDFAQFLD TCCKAADKDT CFSTEGPNLV 600
    TRCKDALA 608
    Length:608
    Mass (Da):68,693
    Last modified:May 24, 2005 - v1
    Checksum:i292F7C7EED3A61B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK131891 mRNA. Translation: BAE20854.1.
    AJ457860 mRNA. Translation: CAD29888.1.
    CH466617 Genomic DNA. Translation: EDL05322.1.
    RefSeqiNP_033784.2. NM_009654.3.
    UniGeneiMm.16773.

    Genome annotation databases

    GeneIDi11657.
    KEGGimmu:11657.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK131891 mRNA. Translation: BAE20854.1 .
    AJ457860 mRNA. Translation: CAD29888.1 .
    CH466617 Genomic DNA. Translation: EDL05322.1 .
    RefSeqi NP_033784.2. NM_009654.3.
    UniGenei Mm.16773.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000031314.

    Protein family/group databases

    Allergomei 755. Mus m 4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 11657.
    KEGGi mmu:11657.

    Organism-specific databases

    CTDi 213.
    MGIi MGI:87991. Alb.

    Phylogenomic databases

    GeneTreei ENSGT00390000000113.
    HOVERGENi HBG004207.
    InParanoidi Q546G4.
    KOi K16141.
    OMAi NCDKSLH.

    Miscellaneous databases

    ChiTaRSi ALB. mouse.
    NextBioi 279275.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q546G4.

    Family and domain databases

    InterProi IPR000264. ALB/AFP/VDB.
    IPR020858. Serum_albumin-like.
    IPR021177. Serum_albumin/AFP.
    IPR020857. Serum_albumin_CS.
    IPR014760. Serum_albumin_N.
    [Graphical view ]
    Pfami PF00273. Serum_albumin. 3 hits.
    [Graphical view ]
    PIRSFi PIRSF002520. Serum_albumin_subgroup. 1 hit.
    PRINTSi PR00802. SERUMALBUMIN.
    SMARTi SM00103. ALBUMIN. 3 hits.
    [Graphical view ]
    SUPFAMi SSF48552. SSF48552. 3 hits.
    PROSITEi PS00212. ALBUMIN_1. 3 hits.
    PS51438. ALBUMIN_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    7. "Mus musculus mRNA coding for serum albumin."
      Le Pogam C., Hilger C., Hentges F.
      Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Balb/cImported.
      Tissue: LiverImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    9. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    10. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: StomachImported.
    11. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.

    Entry informationi

    Entry nameiQ546G4_MOUSE
    AccessioniPrimary (citable) accession number: Q546G4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)