Q546G4 (Q546G4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Albumin 1 EMBL EDL05322.1

Submitted name:
Serum albumin EMBL CAD29888.1

Gene names

Name:	Alb MGI 87991
Synonyms:	alb EMBL CAD29888.1, Alb1 MGI 87991 EMBL EDL05322.1
ORF Names:	mCG_1705 EMBL EDL05322.1

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	608 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Signal EMBL CAD29888.1
Gene Ontology (GO)
Biological_process	cellular response to starvation Inferred from electronic annotation. Source: Compara hemolysis by symbiont of host erythrocytes Inferred from electronic annotation. Source: Compara maintenance of mitochondrion location Inferred from electronic annotation. Source: Compara negative regulation of apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of circadian sleep/wake cycle, non-REM sleep Inferred from electronic annotation. Source: Compara response to mercury ion Inferred from electronic annotation. Source: Compara response to nutrient Inferred from electronic annotation. Source: Compara response to organic substance Inferred from electronic annotation. Source: Compara response to platinum ion Inferred from electronic annotation. Source: Compara transport Inferred from electronic annotation. Source: InterPro
Cellular_component	basement membrane Inferred from electronic annotation. Source: Compara cytoplasm Inferred from direct assay PubMed 11197537PubMed 15576401PubMed 16880525PubMed 8607965. Source: MGI extracellular space Inferred from direct assay PubMed 7798939. Source: MGI protein complex Inferred from electronic annotation. Source: Compara
Molecular_function	DNA binding Inferred from electronic annotation. Source: Compara cell surface binding Inferred from electronic annotation. Source: Compara fatty acid binding Inferred from electronic annotation. Source: Compara oxygen binding Inferred from electronic annotation. Source: Compara pyridoxal phosphate binding Inferred from electronic annotation. Source: Compara toxin binding Inferred from electronic annotation. Source: Compara zinc ion binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential EMBL CAD29888.1
	Chain	19 – 608	590	Potential EMBL CAD29888.1		PRO_5000068495
	Chain	25 – 608	584	serum albumin EMBL CAD29888.1		PRO_5000068496

Sequences

	Sequence		Length	Mass (Da)
	Q546G4 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 292F7C7EED3A61B4	FASTA	608	68,693
	10 20 30 40 50 60 MKWVTFLLLL FVSGSAFSRG VFRREAHKSE IAHRYNDLGE QHFKGLVLIA FSQYLQKCSY 70 80 90 100 110 120 DEHAKLVQEV TDFAKTCVAD ESAANCDKSL HTLFGDKLCA IPNLRENYGE LADCCTKQEP 130 140 150 160 170 180 ERNECFLQHK DDNPSLPPFE RPEAEAMCTS FKENPTTFMG HYLHEVARRH PYFYAPELLY 190 200 210 220 230 240 YAEQYNEILT QCCAEADKES CLTPKLDGVK EKALVSSVRQ RMKCSSMQKF GERAFKAWAV 250 260 270 280 290 300 ARLSQTFPNA DFAEITKLAT DLTKVNKECC HGDLLECADD RAELAKYMCE NQATISSKLQ 310 320 330 340 350 360 TCCDKPLLKK AHCLSEVEHD TMPADLPAIA ADFVEDQEVC KNYAEAKDVF LGTFLYEYSR 370 380 390 400 410 420 RHPDYSVSLL LRLAKKYEAT LEKCCAEANP PACYGTVLAE FQPLVEEPKN LVKTNCDLYE 430 440 450 460 470 480 KLGEYGFQNA ILVRYTQKAP QVSTPTLVEA ARNLGRVGTK CCTLPEDQRL PCVEDYLSAI 490 500 510 520 530 540 LNRVCLLHEK TPVSEHVTKC CSGSLVERRP CFSALTVDET YVPKEFKAET FTFHSDICTL 550 560 570 580 590 600 PEKEKQIKKQ TALAELVKHK PKATAEQLKT VMDDFAQFLD TCCKAADKDT CFSTEGPNLV TRCKDALA

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[6]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL05322.1.
[7]	"Mus musculus mRNA coding for serum albumin." Le Pogam C., Hilger C., Hentges F. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Balb/c EMBL CAD29888.1. Tissue: Liver EMBL CAD29888.1.
[8]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[9]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[10]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE20854.1. Tissue: Stomach EMBL BAE20854.1.
[11]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL05322.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK131891 mRNA. Translation: BAE20854.1. AJ457860 mRNA. Translation: CAD29888.1. CH466617 Genomic DNA. Translation: EDL05322.1.
IPI	IPI00131695.
RefSeq	NP_033784.2. NM_009654.3.
UniGene	Mm.16773.
3D structure databases
SMR	Q546G4. Positions 29-585.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000031314.
Protein family/group databases
Allergome	755. Mus m 4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	11657.
KEGG	mmu:11657.
UCSC	uc008yaz.2. mouse.
Organism-specific databases
CTD	213.
MGI	MGI:87991. Alb.
Phylogenomic databases
GeneTree	ENSGT00390000000113.
HOVERGEN	HBG004207.
InParanoid	Q546G4.
KO	K16141.
OMA	NCDKSLH.
Gene expression databases
Genevestigator	Q546G4.
Family and domain databases
InterPro	IPR000264. ALB/AFP/VDB. IPR020858. Serum_albumin-like. IPR021177. Serum_albumin/AFP. IPR020857. Serum_albumin_CS. IPR014760. Serum_albumin_N. [Graphical view]
Pfam	PF00273. Serum_albumin. 3 hits. [Graphical view]
PIRSF	PIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTS	PR00802. SERUMALBUMIN.
SMART	SM00103. ALBUMIN. 3 hits. [Graphical view]
SUPFAM	SSF48552. Serum_albumin. 3 hits.
PROSITE	PS00212. ALBUMIN_1. 3 hits. PS51438. ALBUMIN_2. 3 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ALB. mouse.
NextBio	279275.
SOURCE	Search...

Entry information

Entry name

Q546G4_MOUSE

Accession

Primary (citable) accession number: Q546G4

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)