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Protein
Submitted name:

CD33 antigen (Gp67)

Gene

CD33

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
CD33 antigen (Gp67)Imported
Submitted name:
CD33 antigen (Gp67), isoform CRA_bImported
Gene namesi
Name:CD33Imported
ORF Names:hCG_91950Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000105383.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei261 – 282HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26210

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_501430957717 – 364Sequence analysisAdd BLAST348

Expressioni

Gene expression databases

BgeeiENSG00000105383
ExpressionAtlasiQ546G0 baseline and differential

Structurei

3D structure databases

SMRiQ546G0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 135Ig-likeInterPro annotationAdd BLAST117
Domaini145 – 228Ig-likeInterPro annotationAdd BLAST84

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJT6 Eukaryota
ENOG410YKZU LUCA
HOVERGENiHBG036161
KOiK06473
OMAiASLNFHG
OrthoDBiEOG091G0M13

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
PfamiView protein in Pfam
PF00047 ig, 1 hit
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

Sequencei

Sequence statusi: Complete.

Q546G0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLLLLLPLL WAGALAMDPN FWLQVQESVT VQEGLCVLVP CTFFHPIPYY
60 70 80 90 100
DKNSPVHGYW FREGAIISRD SPVATNKLDQ EVQEETQGRF RLLGDPSRNN
110 120 130 140 150
CSLSIVDARR RDNGSYFFRM ERGSTKYSYK SPQLSVHVTD LTHRPKILIP
160 170 180 190 200
GTLEPGHSKN LTCSVSWACE QGTPPIFSWL SAAPTSLGPR TTHSSVLIIT
210 220 230 240 250
PRPQDHGTNL TCQVKFAGAG VTTERTIQLN VTYVPQNPTT GIFPGDGSGK
260 270 280 290 300
QETRAGVVHG AIGGAGVTAL LALCLCLIFF IVKTHRRKAA RTAVGRNDTH
310 320 330 340 350
PTTGSASPKH QKKSKLHGPT ETSSCSGAAP TVEMDEELHY ASLNFHGMNP
360
SKDTSTEYSE VRTQ
Length:364
Mass (Da):39,825
Last modified:May 24, 2005 - v1
Checksum:i1C73E588240FBAD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ491319 Genomic DNA Translation: CAD36509.1
CH471135 Genomic DNA Translation: EAW71995.1
RefSeqiNP_001763.3, NM_001772.3
XP_011525834.1, XM_011527532.2
UniGeneiHs.83731

Genome annotation databases

GeneIDi945
KEGGihsa:945
UCSCiuc002pwa.3 human

Similar proteinsi

Entry informationi

Entry nameiQ546G0_HUMAN
AccessioniPrimary (citable) accession number: Q546G0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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