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Q546D7

- Q546D7_HUMAN

UniProt

Q546D7 - Q546D7_HUMAN

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Protein
Submitted name:

Ameloblastin

Gene

AMBN

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. structural constituent of tooth enamel Source: InterPro

GO - Biological processi

  1. cell adhesion Source: Ensembl
  2. cell proliferation Source: Ensembl
  3. odontogenesis of dentin-containing tooth Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AmeloblastinImported
Submitted name:
cDNA, FLJ95827, Homo sapiens ameloblastin, enamel matrix protein (AMBN), mRNAImported
Gene namesi
Name:AMBNImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24758.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626 PotentialImportedAdd
BLAST
Chaini27 – 447421ameloblastinImportedPRO_5000070408Add
BLAST

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

HOVERGENiHBG007128.
OMAiAMGGDFT.

Family and domain databases

InterProiIPR007798. Amelin.
[Graphical view]
PANTHERiPTHR14115. PTHR14115. 1 hit.
PfamiPF05111. Amelin. 2 hits.
[Graphical view]
SMARTiSM00817. Amelin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q546D7-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSASKIPLFK MKDLILILCL LEMSFAVPFF PQQSGTPGMA SLSLETMRQL
60 70 80 90 100
GSLQRLNTLS QYSRYGFGKS FNSLWMHGLL PPHSSLPWMR PREHETQQYE
110 120 130 140 150
YSLPVHPPPL PSQPSLKPQQ PGLKPFLQSA AATTNQATAL KEALQPPIHL
160 170 180 190 200
GHLPLQEGEL PLVQQQVAPS DKPPKPELPG VDFADPQGPS LPGMDFPDPQ
210 220 230 240 250
GPSLPGLDFA DPQGSTIFQI ARLISHGPMP QNKQSPLYPG MLYVPFGANQ
260 270 280 290 300
LNAPARLGIM SSEEVAGGRE DPMAYGAMFP GFGGMRPGFE GMPHNPAMGG
310 320 330 340 350
DFTLEFDSPV AATKGPENEE GGAQGSPMPE ANPDNLENPA FLTELEPAPH
360 370 380 390 400
AGLLALPKDD IPGLPRSPSG KMKGLPSVTP AAADPLMTPE LADVYRTYDA
410 420 430 440
DMTTSVDFQE EATMDTTMAP NSLQTSMPGN KAQEPEMMHD AWHFQEP
Length:447
Mass (Da):48,283
Last modified:May 24, 2005 - v1
Checksum:iD5CAFAA76B55758C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314918 mRNA. Translation: BAG37429.1.
AJ537437 mRNA. Translation: CAD60938.1.
RefSeqiNP_057603.1. NM_016519.5.
UniGeneiHs.272396.

Genome annotation databases

GeneIDi258.
KEGGihsa:258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314918 mRNA. Translation: BAG37429.1 .
AJ537437 mRNA. Translation: CAD60938.1 .
RefSeqi NP_057603.1. NM_016519.5.
UniGenei Hs.272396.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 258.
KEGGi hsa:258.

Organism-specific databases

CTDi 258.
PharmGKBi PA24758.

Phylogenomic databases

HOVERGENi HBG007128.
OMAi AMGGDFT.

Miscellaneous databases

GenomeRNAii 258.
NextBioi 1017.

Family and domain databases

InterProi IPR007798. Amelin.
[Graphical view ]
PANTHERi PTHR14115. PTHR14115. 1 hit.
Pfami PF05111. Amelin. 2 hits.
[Graphical view ]
SMARTi SM00817. Amelin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Ameloblastin expression in human tooth roots."
    Cerny R., Vrzakova R., Cerna E., Kulda V.
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Tooth rootImported.
  2. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Corpus callosumImported.

Entry informationi

Entry nameiQ546D7_HUMAN
AccessioniPrimary (citable) accession number: Q546D7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 26, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.