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Q546D7

- Q546D7_HUMAN

UniProt

Q546D7 - Q546D7_HUMAN

Protein
Submitted name:

Ameloblastin

Gene

AMBN

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. structural constituent of tooth enamel Source: InterPro

    GO - Biological processi

    1. cell adhesion Source: Ensembl
    2. cell proliferation Source: Ensembl
    3. odontogenesis of dentin-containing tooth Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AmeloblastinImported
    Submitted name:
    cDNA, FLJ95827, Homo sapiens ameloblastin, enamel matrix protein (AMBN), mRNAImported
    Gene namesi
    Name:AMBNImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA24758.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626 PotentialImportedAdd
    BLAST
    Chaini27 – 447421ameloblastinImportedPRO_5000070408Add
    BLAST

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    HOVERGENiHBG007128.
    OMAiAMGGDFT.
    PhylomeDBiQ546D7.

    Family and domain databases

    InterProiIPR007798. Amelin.
    [Graphical view]
    PANTHERiPTHR14115. PTHR14115. 1 hit.
    PfamiPF05111. Amelin. 2 hits.
    [Graphical view]
    SMARTiSM00817. Amelin. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q546D7-1 [UniParc]FASTAAdd to Basket

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    MSASKIPLFK MKDLILILCL LEMSFAVPFF PQQSGTPGMA SLSLETMRQL    50
    GSLQRLNTLS QYSRYGFGKS FNSLWMHGLL PPHSSLPWMR PREHETQQYE 100
    YSLPVHPPPL PSQPSLKPQQ PGLKPFLQSA AATTNQATAL KEALQPPIHL 150
    GHLPLQEGEL PLVQQQVAPS DKPPKPELPG VDFADPQGPS LPGMDFPDPQ 200
    GPSLPGLDFA DPQGSTIFQI ARLISHGPMP QNKQSPLYPG MLYVPFGANQ 250
    LNAPARLGIM SSEEVAGGRE DPMAYGAMFP GFGGMRPGFE GMPHNPAMGG 300
    DFTLEFDSPV AATKGPENEE GGAQGSPMPE ANPDNLENPA FLTELEPAPH 350
    AGLLALPKDD IPGLPRSPSG KMKGLPSVTP AAADPLMTPE LADVYRTYDA 400
    DMTTSVDFQE EATMDTTMAP NSLQTSMPGN KAQEPEMMHD AWHFQEP 447
    Length:447
    Mass (Da):48,283
    Last modified:May 24, 2005 - v1
    Checksum:iD5CAFAA76B55758C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK314918 mRNA. Translation: BAG37429.1.
    AJ537437 mRNA. Translation: CAD60938.1.
    RefSeqiNP_057603.1. NM_016519.5.
    UniGeneiHs.272396.

    Genome annotation databases

    GeneIDi258.
    KEGGihsa:258.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK314918 mRNA. Translation: BAG37429.1 .
    AJ537437 mRNA. Translation: CAD60938.1 .
    RefSeqi NP_057603.1. NM_016519.5.
    UniGenei Hs.272396.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 258.
    KEGGi hsa:258.

    Organism-specific databases

    CTDi 258.
    PharmGKBi PA24758.

    Phylogenomic databases

    HOVERGENi HBG007128.
    OMAi AMGGDFT.
    PhylomeDBi Q546D7.

    Miscellaneous databases

    GenomeRNAii 258.
    NextBioi 1017.

    Family and domain databases

    InterProi IPR007798. Amelin.
    [Graphical view ]
    PANTHERi PTHR14115. PTHR14115. 1 hit.
    Pfami PF05111. Amelin. 2 hits.
    [Graphical view ]
    SMARTi SM00817. Amelin. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Ameloblastin expression in human tooth roots."
      Cerny R., Vrzakova R., Cerna E., Kulda V.
      Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Tooth rootImported.
    2. "NEDO functional analysis of protein and research application project."
      Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
      Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Corpus callosumImported.

    Entry informationi

    Entry nameiQ546D7_HUMAN
    AccessioniPrimary (citable) accession number: Q546D7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.