Q546D7 (Q546D7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ameloblastin EMBL CAD60938.1

Submitted name:
cDNA, FLJ95827, Homo sapiens ameloblastin, enamel matrix protein (AMBN), mRNA EMBL BAG37429.1

Gene names

Name:

AMBN EMBL CAD60938.1

Organism

Homo sapiens (Human) EMBL CAD60938.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Signal EMBL CAD60938.1
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara odontogenesis of dentin-containing tooth Inferred from electronic annotation. Source: InterPro
Molecular_function	structural constituent of tooth enamel Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential EMBL CAD60938.1
	Chain	27 – 447	421	ameloblastin EMBL CAD60938.1		PRO_5000070408

Sequences

	Sequence		Length	Mass (Da)
	Q546D7 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: D5CAFAA76B55758C	FASTA	447	48,283
	10 20 30 40 50 60 MSASKIPLFK MKDLILILCL LEMSFAVPFF PQQSGTPGMA SLSLETMRQL GSLQRLNTLS 70 80 90 100 110 120 QYSRYGFGKS FNSLWMHGLL PPHSSLPWMR PREHETQQYE YSLPVHPPPL PSQPSLKPQQ 130 140 150 160 170 180 PGLKPFLQSA AATTNQATAL KEALQPPIHL GHLPLQEGEL PLVQQQVAPS DKPPKPELPG 190 200 210 220 230 240 VDFADPQGPS LPGMDFPDPQ GPSLPGLDFA DPQGSTIFQI ARLISHGPMP QNKQSPLYPG 250 260 270 280 290 300 MLYVPFGANQ LNAPARLGIM SSEEVAGGRE DPMAYGAMFP GFGGMRPGFE GMPHNPAMGG 310 320 330 340 350 360 DFTLEFDSPV AATKGPENEE GGAQGSPMPE ANPDNLENPA FLTELEPAPH AGLLALPKDD 370 380 390 400 410 420 IPGLPRSPSG KMKGLPSVTP AAADPLMTPE LADVYRTYDA DMTTSVDFQE EATMDTTMAP 430 440 NSLQTSMPGN KAQEPEMMHD AWHFQEP

References

[1]	"Ameloblastin expression in human tooth roots." Cerny R., Vrzakova R., Cerna E., Kulda V. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Tooth root EMBL CAD60938.1.
[2]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Corpus callosum EMBL BAG37429.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK314918 mRNA. Translation: BAG37429.1. AJ537437 mRNA. Translation: CAD60938.1.
IPI	IPI00009759.
RefSeq	NP_057603.1. NM_016519.5.
UniGene	Hs.272396.
3D structure databases
ProteinModelPortal	Q546D7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q546D7.
Proteomic databases
PRIDE	Q546D7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	258.
KEGG	hsa:258.
Organism-specific databases
CTD	258.
PharmGKB	PA24758.
Phylogenomic databases
HOVERGEN	HBG007128.
OMA	WMHGLLP.
PhylomeDB	Q546D7.
Gene expression databases
ArrayExpress	Q546D7.
Bgee	Q546D7.
Family and domain databases
InterPro	IPR007798. Amelin. [Graphical view]
PANTHER	PTHR14115. PTHR14115. 1 hit.
Pfam	PF05111. Amelin. 2 hits. [Graphical view]
SMART	SM00817. Amelin. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	258.
NextBio	1017.

Entry information

Entry name

Q546D7_HUMAN

Accession

Primary (citable) accession number: Q546D7

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	October 3, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.