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Protein
Submitted name:

Ameloblastin

Gene

AMBN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. structural constituent of tooth enamel Source: InterPro

GO - Biological processi

  1. cell adhesion Source: Ensembl
  2. cell proliferation Source: Ensembl
  3. odontogenesis of dentin-containing tooth Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AmeloblastinImported
Submitted name:
cDNA, FLJ95827, Homo sapiens ameloblastin, enamel matrix protein (AMBN), mRNAImported
Gene namesi
Name:AMBNImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24758.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626 PotentialImportedAdd
BLAST
Chaini27 – 447421ameloblastinImportedPRO_5000070408Add
BLAST

Proteomic databases

PRIDEiQ546D7.

Expressioni

Gene expression databases

BgeeiQ546D7.
ExpressionAtlasiQ546D7. differential.

Structurei

3D structure databases

ProteinModelPortaliQ546D7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

HOVERGENiHBG007128.
OMAiAMGGDFT.
PhylomeDBiQ546D7.

Family and domain databases

InterProiIPR007798. Amelin.
[Graphical view]
PANTHERiPTHR14115. PTHR14115. 1 hit.
PfamiPF05111. Amelin. 2 hits.
[Graphical view]
SMARTiSM00817. Amelin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q546D7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASKIPLFK MKDLILILCL LEMSFAVPFF PQQSGTPGMA SLSLETMRQL
60 70 80 90 100
GSLQRLNTLS QYSRYGFGKS FNSLWMHGLL PPHSSLPWMR PREHETQQYE
110 120 130 140 150
YSLPVHPPPL PSQPSLKPQQ PGLKPFLQSA AATTNQATAL KEALQPPIHL
160 170 180 190 200
GHLPLQEGEL PLVQQQVAPS DKPPKPELPG VDFADPQGPS LPGMDFPDPQ
210 220 230 240 250
GPSLPGLDFA DPQGSTIFQI ARLISHGPMP QNKQSPLYPG MLYVPFGANQ
260 270 280 290 300
LNAPARLGIM SSEEVAGGRE DPMAYGAMFP GFGGMRPGFE GMPHNPAMGG
310 320 330 340 350
DFTLEFDSPV AATKGPENEE GGAQGSPMPE ANPDNLENPA FLTELEPAPH
360 370 380 390 400
AGLLALPKDD IPGLPRSPSG KMKGLPSVTP AAADPLMTPE LADVYRTYDA
410 420 430 440
DMTTSVDFQE EATMDTTMAP NSLQTSMPGN KAQEPEMMHD AWHFQEP
Length:447
Mass (Da):48,283
Last modified:May 24, 2005 - v1
Checksum:iD5CAFAA76B55758C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314918 mRNA. Translation: BAG37429.1.
AJ537437 mRNA. Translation: CAD60938.1.
RefSeqiNP_057603.1. NM_016519.5.
UniGeneiHs.272396.

Genome annotation databases

GeneIDi258.
KEGGihsa:258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314918 mRNA. Translation: BAG37429.1.
AJ537437 mRNA. Translation: CAD60938.1.
RefSeqiNP_057603.1. NM_016519.5.
UniGeneiHs.272396.

3D structure databases

ProteinModelPortaliQ546D7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ546D7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi258.
KEGGihsa:258.

Organism-specific databases

CTDi258.
PharmGKBiPA24758.

Phylogenomic databases

HOVERGENiHBG007128.
OMAiAMGGDFT.
PhylomeDBiQ546D7.

Miscellaneous databases

GenomeRNAii258.
NextBioi1017.

Gene expression databases

BgeeiQ546D7.
ExpressionAtlasiQ546D7. differential.

Family and domain databases

InterProiIPR007798. Amelin.
[Graphical view]
PANTHERiPTHR14115. PTHR14115. 1 hit.
PfamiPF05111. Amelin. 2 hits.
[Graphical view]
SMARTiSM00817. Amelin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Ameloblastin expression in human tooth roots."
    Cerny R., Vrzakova R., Cerna E., Kulda V.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Tooth rootImported.
  2. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Corpus callosumImported.

Entry informationi

Entry nameiQ546D7_HUMAN
AccessioniPrimary (citable) accession number: Q546D7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: April 1, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.