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Protein

DNA-binding protein SATB

Gene

Satb2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi614 – 674HomeoboxPROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-binding protein SATBUniRule annotation
Alternative name(s):
Special AT-rich sequence-binding proteinUniRule annotation
Gene namesi
Name:Satb2Imported
Synonyms:SATB2Imported
ORF Names:mCG_113907Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2679336. Satb2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000038331.

Structurei

3D structure databases

SMRiQ546B3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini350 – 437CUTInterPro annotationAdd BLAST88
Domaini473 – 560CUTInterPro annotationAdd BLAST88
Domaini612 – 673HomeoboxInterPro annotationAdd BLAST62

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410ISJ9. Eukaryota.
ENOG41113K2. LUCA.
HOVERGENiHBG054240.
OMAiCVVEQSD.
OrthoDBiEOG091G02HV.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR003350. CUT_dom.
IPR032355. CUTL.
IPR009057. Homeobox-like_sf.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom_sf.
IPR032392. ULD.
PfamiView protein in Pfam
PF02376. CUT. 2 hits.
PF16557. CUTL. 1 hit.
PF00046. Homeobox. 1 hit.
PF16534. ULD. 1 hit.
SMARTiView protein in SMART
SM01109. CUT. 2 hits.
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 2 hits.
PROSITEiView protein in PROSITE
PS51042. CUT. 2 hits.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q546B3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERRSESPCL RDSPDRRSGS PDVKGPPPVK VARLEQNGSP MGARGRPNGA
60 70 80 90 100
VAKAVGGLMI PVFCVVEQLD GSLEYDNREE HAEFVLVRKD VLFSQLVETA
110 120 130 140 150
LLALGYSHSS AAQAQGIIKL GRWNPLPLSY VTDAPDATVA DMLQDVYHVV
160 170 180 190 200
TLKIQLQSCS KLEDLPAEQW NHATVRNALK ELLKEMNQST LAKECPLSQS
210 220 230 240 250
MISSIVNSTY YANVSATKCQ EFGRWYKKYK KIKVERVERE NLSDYCVLGQ
260 270 280 290 300
RPMHLPNMNQ LASLGKTNEQ SPHSQIHHST PIRNQVPALQ PIMSPGLLSP
310 320 330 340 350
QLSPQLVRQQ IAMAHLINQQ IAVSRLLAHQ HPQAINQQFL NHPPIPRAVK
360 370 380 390 400
PEPTNSSVEV SPDIYQQVRD ELKRASVSQA VFARVAFNRT QGLLSEILRK
410 420 430 440 450
EEDPRTASQS LLVNLRAMQN FLNLPEVERD RIYQDERERS MNPNVSMVSS
460 470 480 490 500
ASSSPSSSRT PQAKTSTPTT DLPIKVDGAN VNITAAIYDE IQQEMKRAKV
510 520 530 540 550
SQALFAKVAA NKSQGWLCEL LRWKENPSPE NRTLWENLCT IRRFLNLPQH
560 570 580 590 600
ERDVIYEEES RHHHSERMQH VVQLPPEPVQ VLHRQQSQPT KESSPPREEA
610 620 630 640 650
PPPPPPTEDS CAKKPRSRTK ISLEALGILQ SFIHDVGLYP DQEAIHTLSA
660 670 680 690 700
QLDLPKHTII KFFQNQRYHV KHHGKLKEHL GSAVDVAEYK DEELLTESEE
710 720 730
NDSEEGSEEM YKVEAEEENA DKSKAAPAET DQR
Length:733
Mass (Da):82,559
Last modified:May 24, 2005 - v1
Checksum:i153CFD1CC3491F25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138625 mRNA. Translation: AAI38626.1.
BC138626 mRNA. Translation: AAI38627.1.
AJ606045 mRNA. Translation: CAE54289.1.
CH466548 Genomic DNA. Translation: EDL00043.1.
RefSeqiNP_631885.1. NM_139146.2.
XP_017175119.1. XM_017319630.1.
XP_017175120.1. XM_017319631.1.
UniGeneiMm.145599.

Genome annotation databases

GeneIDi212712.
KEGGimmu:212712.

Similar proteinsi

Entry informationi

Entry nameiQ546B3_MOUSE
AccessioniPrimary (citable) accession number: Q546B3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)