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Protein
Submitted name:

Bcl2-associated X protein, isoform CRA_b

Gene

Bax

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Bcl2-associated X protein, isoform CRA_bImported
Gene namesi
Name:BaxImported
ORF Names:mCG_23178Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99702 Bax

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei170 – 188HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiQ544Z6

Expressioni

Gene expression databases

BgeeiENSMUSG00000003873
ExpressionAtlasiQ544Z6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ544Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IWQJ Eukaryota
ENOG4112738 LUCA
HOVERGENiHBG003606
KOiK02159
OMAiVINWIRE
OrthoDBiEOG091G0YWR

Family and domain databases

Gene3Di1.10.437.10, 1 hit
InterProiView protein in InterPro
IPR026304 BAX
IPR002475 Bcl2-like
IPR020717 Bcl2_BH1_motif_CS
IPR020726 Bcl2_BH2_motif_CS
IPR020728 Bcl2_BH3_motif_CS
IPR036834 Blc2-like_sf
IPR026298 Blc2_fam
PANTHERiPTHR11256 PTHR11256, 1 hit
PTHR11256:SF42 PTHR11256:SF42, 1 hit
PfamiView protein in Pfam
PF00452 Bcl-2, 1 hit
PRINTSiPR01862 BCL2FAMILY
SUPFAMiSSF56854 SSF56854, 1 hit
PROSITEiView protein in PROSITE
PS50062 BCL2_FAMILY, 1 hit
PS01080 BH1, 1 hit
PS01258 BH2, 1 hit
PS01259 BH3, 1 hit

Sequencei

Sequence statusi: Complete.

Q544Z6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGSGEQLGS GGPTSSEQIM KTGAFLLQGF IQDRAGRMAG ETPELTLEQP
60 70 80 90 100
PQDASTKKLS ECLRRIGDEL DSNMELQRMI ADVDTDSPRE VFFRVAADMF
110 120 130 140 150
ADGNFNWGRV VALFYFASKL VLKALCTKVP ELIRTIMGWT LDFLRERLLV
160 170 180 190
WIQDQGGWEG LLSYFGTPTW QTVTIFVAGV LTASLTIWKK MG
Length:192
Mass (Da):21,395
Last modified:May 24, 2005 - v1
Checksum:iD2E0B3566579FAFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK013298 mRNA Translation: BAB28776.1
AK149994 mRNA Translation: BAE29222.1
CH466603 Genomic DNA Translation: EDL22858.1
RefSeqiNP_031553.1, NM_007527.3
UniGeneiMm.19904

Genome annotation databases

GeneIDi12028
KEGGimmu:12028

Similar proteinsi

Entry informationi

Entry nameiQ544Z6_MOUSE
AccessioniPrimary (citable) accession number: Q544Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health