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Protein
Submitted name:

Cofilin 1, non-muscle

Gene

Cfl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cofilin 1, non-muscleImported
Gene namesi
Name:Cfl1Imported
ORF Names:mCG_11768Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:101757. Cfl1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ544Y7.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ544Y7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 153ADF-HInterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the actin-binding proteins ADF family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1735. Eukaryota.
ENOG41122P5. LUCA.
HOVERGENiHBG000381.
KOiK05765.

Family and domain databases

CDDicd11286. ADF_cofilin_like. 1 hit.
Gene3Di3.40.20.10. 1 hit.
InterProiView protein in InterPro
IPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom.
IPR017904. ADF/Cofilin.
IPR027234. Cofilin_1.
PANTHERiPTHR11913. PTHR11913. 1 hit.
PTHR11913:SF37. PTHR11913:SF37. 1 hit.
PfamiView protein in Pfam
PF00241. Cofilin_ADF. 1 hit.
PRINTSiPR00006. COFILIN.
SMARTiView protein in SMART
SM00102. ADF. 1 hit.
PROSITEiView protein in PROSITE
PS51263. ADF_H. 1 hit.

Sequencei

Sequence statusi: Complete.

Q544Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE
60 70 80 90 100
EGKEILVGDV GQTVDDPYTT FVKMLPDKDC RYALYDATYE TKESKKEDLV
110 120 130 140 150
FIFWAPENAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA
160
EKLGGSAVIS LEGKPL
Length:166
Mass (Da):18,560
Last modified:May 24, 2005 - v1
Checksum:i19834E8CA80747B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC094357 mRNA. Translation: AAH94357.1.
AK013943 mRNA. Translation: BAB29074.1.
AK050651 mRNA. Translation: BAC34363.1.
AK088633 mRNA. Translation: BAC40467.1.
AK088793 mRNA. Translation: BAC40575.1.
AK167795 mRNA. Translation: BAE39825.1.
CH466612 Genomic DNA. Translation: EDL33144.1.
RefSeqiNP_031713.1. NM_007687.5.
UniGeneiMm.329655.

Genome annotation databases

GeneIDi12631.
KEGGimmu:12631.

Similar proteinsi

Entry informationi

Entry nameiQ544Y7_MOUSE
AccessioniPrimary (citable) accession number: Q544Y7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)