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Protein

alpha-1,2-Mannosidase

Gene

Man1a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:Man1aImported
ORF Names:mCG_50876Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104677. Man1a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiQ544T7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000003746.

Structurei

3D structure databases

SMRiQ544T7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili116 – 147Sequence analysisAdd BLAST32

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
HOVERGENiHBG052389.
KOiK01230.
OMAiDHKPGPG.
OrthoDBiEOG091G04C8.

Family and domain databases

InterProiView protein in InterPro
IPR001382. Glyco_hydro_47.
IPR036026. Seven-hairpin_glycosidases.
PfamiView protein in Pfam
PF01532. Glyco_hydro_47. 1 hit.
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

Q544T7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVGGLLPLF SSPGGGGLGS GLGGGLGGGR KGSGPAAFRL TEKFVLLLVF
60 70 80 90 100
SAFITLCFGA IFFLPDSSKL LSGVLFHSNP ALQPPAEHKP GLGARAEDAA
110 120 130 140 150
EGRVRHREEG APGDPGAGLE DNLARIRENH ERALREAKET LQKLPEEIQR
160 170 180 190 200
DILLEKEKVA QDQLRDKDLF RGLPKVDFLP PVGVENREPA DATIREKRAK
210 220 230 240 250
IKEMMTHAWN NYKRYAWGLN ELKPISKEGH SSSLFGNIKG ATIVDALDTL
260 270 280 290 300
FIMGMKTEFQ EAKSWIKKYL DFNVNAEVSV FEVNIRFVGG LLSAYYLSGE
310 320 330 340 350
EIFRKKAVEL GVKLLPAFHT PSGIPWALLN MKSGIGRNWP WASGGSSILA
360 370 380 390 400
EFGTLHLEFM HLSHLSGDPV FAEKVMKIRT VLNKLDKPEG LYPNYLNPSS
410 420 430 440 450
GQWGQHHVSV GGLGDSFYEY LLKAWLMSDK TDLEAKKMYF DAVQAIETHL
460 470 480 490 500
IRKSSGGLTY IAEWKGGLLE HKMGHLTCFA GGMFALGADG APEARAQHYL
510 520 530 540 550
ELGAEIARTC HESYNRTYVK LGPEAFRFDG GVEAIATRQN EKYYILRPEV
560 570 580 590 600
IETYMYMWRL THDPKYRTWA WEAVEALESH CRVNGGYSGL RDVYIARESY
610 620 630 640 650
DDVQQSFFLA ETLKYLYLIF SDDDLLPLEH WIFNTEAHPF PILREQKKEI

DGKEK
Length:655
Mass (Da):73,276
Last modified:May 24, 2005 - v1
Checksum:i15AF658364930BF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031038 mRNA. Translation: BAC27225.1.
AK154820 mRNA. Translation: BAE32852.1.
CH466540 Genomic DNA. Translation: EDL05098.1.
CH466540 Genomic DNA. Translation: EDL05100.1.
RefSeqiNP_032574.1. NM_008548.4.
XP_006512632.1. XM_006512569.3.
UniGeneiMm.117294.

Genome annotation databases

GeneIDi17155.
KEGGimmu:17155.

Similar proteinsi

Entry informationi

Entry nameiQ544T7_MOUSE
AccessioniPrimary (citable) accession number: Q544T7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)