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Protein
Submitted name:

Putative uncharacterized protein

Gene

Ddr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Ddr1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99216. Ddr1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei415 – 43723HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 874853Sequence analysisPRO_5006965724Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiQ544T2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003628.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 186155F5/8 type CInterPro annotationAdd
BLAST
Domaini571 – 866296Protein kinaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 F5/8 type C domain.UniRule annotation
Contains protein kinase domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1094. Eukaryota.
ENOG410XQAI. LUCA.
GeneTreeiENSGT00760000118818.
HOVERGENiHBG005461.
KOiK05124.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR029553. DDR1/DDR2.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR002011. Tyr_kinase_rcpt_2_CS.
[Graphical view]
PANTHERiPTHR24416:SF295. PTHR24416:SF295. 5 hits.
PfamiPF00754. F5_F8_type_C. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SMARTiSM00231. FA58C. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS00239. RECEPTOR_TYR_KIN_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q544T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTGTLSSLL LLLLLVTIGD ADMKGHFDPA KCRYALGMQD RTIPDSDISV
60 70 80 90 100
SSSWSDSTAA RHSRLESSDG DGAWCPAGPV FPKEEEYLQV DLRRLHLVAL
110 120 130 140 150
VGTQGRHAGG LGKEFSRSYR LRYSRDGRRW MDWKDRWGQE VISGNEDPGG
160 170 180 190 200
VVLKDLGPPM VARLVRFYPR ADRVMSVCLR VELYGCLWRD GLLSYTAPVG
210 220 230 240 250
QTMQLSEVMV HLNDSTYDGY TAGGLQYGGL GQLADGVVGL DDFRQSQELR
260 270 280 290 300
VWPGYDYVGW SNQSFPTGYV EMEFEFDRLR TFQTMQVHCN NMHTLGARLP
310 320 330 340 350
GGVECRFKRG PAMAWEGEPV RHALGGSLGD PRARAISVPL GGHVGRFLQC
360 370 380 390 400
RFLFAGPWLL FSEISFISDV VNDSSDTFPP APWWPPGPPP TNFSSLELEP
410 420 430 440 450
RGQQPVAKAE GSPTAILIGC LVAIILLLLL IIALMLWRLH WRRLLSKAER
460 470 480 490 500
RVLEEELTVH LSVPGDTILI NNRPGPREPP PYQEPRPRGT PPHSAPCVPN
510 520 530 540 550
GSACSGDYME PEKPGAPLLP PPPQNSVPHY AEADIVTLQG VTGGNTYAVP
560 570 580 590 600
ALPPGAVGDG PPRVDFPRSR LRFKEKLGEG QFGEVHLCEV EDPQDLVSSD
610 620 630 640 650
FPISVHKGHP LLVAVKILRP DATKNARNDF LKEVKIMSRL KDPNIIRLLG
660 670 680 690 700
VCVQDDPLCM ITDYMENGDL NQFLSARQLE NKATQGLSGD TESDQGPTIS
710 720 730 740 750
YPMLLHVGAQ IASGMRYLAT LNFVHRDLAT RNCLVGENFT IKIADFGMSR
760 770 780 790 800
NLYAGDYYRV QGRAVLPIRW MAWECILMGK FTTASDVWAF GVTLWEVLML
810 820 830 840 850
CRSQPFGQLT DEQVIENAGE FFRDQGRQVY LSRPPACPQT LYELMLRCWS
860 870
REPEQRPPFA QLHRFLADDA LNTV
Length:874
Mass (Da):97,207
Last modified:May 24, 2005 - v1
Checksum:iA649B2FCE360BA5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031442 mRNA. Translation: BAC27407.1.
AK143088 mRNA. Translation: BAE25267.1.
RefSeqiNP_001185760.1. NM_001198831.1.
NP_001185762.1. NM_001198833.1.
NP_031610.1. NM_007584.2.
NP_766550.1. NM_172962.1.
XP_006523601.1. XM_006523538.2.
UniGeneiMm.5021.

Genome annotation databases

GeneIDi12305.
KEGGimmu:12305.
UCSCiuc008cii.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031442 mRNA. Translation: BAC27407.1.
AK143088 mRNA. Translation: BAE25267.1.
RefSeqiNP_001185760.1. NM_001198831.1.
NP_001185762.1. NM_001198833.1.
NP_031610.1. NM_007584.2.
NP_766550.1. NM_172962.1.
XP_006523601.1. XM_006523538.2.
UniGeneiMm.5021.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003628.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12305.
KEGGimmu:12305.
UCSCiuc008cii.2. mouse.

Organism-specific databases

CTDi780.
MGIiMGI:99216. Ddr1.

Phylogenomic databases

eggNOGiKOG1094. Eukaryota.
ENOG410XQAI. LUCA.
GeneTreeiENSGT00760000118818.
HOVERGENiHBG005461.
KOiK05124.

Miscellaneous databases

ChiTaRSiDdr1. mouse.
NextBioi280834.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiQ544T2. baseline and differential.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR029553. DDR1/DDR2.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR002011. Tyr_kinase_rcpt_2_CS.
[Graphical view]
PANTHERiPTHR24416:SF295. PTHR24416:SF295. 5 hits.
PfamiPF00754. F5_F8_type_C. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SMARTiSM00231. FA58C. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS00239. RECEPTOR_TYR_KIN_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: EyeballImported and TestisImported.

Entry informationi

Entry nameiQ544T2_MOUSE
AccessioniPrimary (citable) accession number: Q544T2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 11, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.