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Protein
Submitted name:

Uncharacterized protein

Gene

Ddr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Ddr1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99216. Ddr1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei415 – 437HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501084402322 – 874Sequence analysisAdd BLAST853

Proteomic databases

MaxQBiQ544T2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000003534.

Structurei

3D structure databases

SMRiQ544T2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 186F5/8 type CInterPro annotationAdd BLAST155
Domaini571 – 866Protein kinaseInterPro annotationAdd BLAST296

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1094. Eukaryota.
ENOG410XQAI. LUCA.
HOVERGENiHBG005461.
KOiK05124.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiView protein in InterPro
IPR029553. DDR1.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR002011. Tyr_kinase_rcpt_2_CS.
PANTHERiPTHR24416:SF449. PTHR24416:SF449. 1 hit.
PfamiView protein in Pfam
PF00754. F5_F8_type_C. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PRINTSiPR00109. TYRKINASE.
SMARTiView protein in SMART
SM00231. FA58C. 1 hit.
SM00219. TyrKc. 1 hit.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS00239. RECEPTOR_TYR_KIN_II. 1 hit.

Sequencei

Sequence statusi: Complete.

Q544T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTGTLSSLL LLLLLVTIGD ADMKGHFDPA KCRYALGMQD RTIPDSDISV
60 70 80 90 100
SSSWSDSTAA RHSRLESSDG DGAWCPAGPV FPKEEEYLQV DLRRLHLVAL
110 120 130 140 150
VGTQGRHAGG LGKEFSRSYR LRYSRDGRRW MDWKDRWGQE VISGNEDPGG
160 170 180 190 200
VVLKDLGPPM VARLVRFYPR ADRVMSVCLR VELYGCLWRD GLLSYTAPVG
210 220 230 240 250
QTMQLSEVMV HLNDSTYDGY TAGGLQYGGL GQLADGVVGL DDFRQSQELR
260 270 280 290 300
VWPGYDYVGW SNQSFPTGYV EMEFEFDRLR TFQTMQVHCN NMHTLGARLP
310 320 330 340 350
GGVECRFKRG PAMAWEGEPV RHALGGSLGD PRARAISVPL GGHVGRFLQC
360 370 380 390 400
RFLFAGPWLL FSEISFISDV VNDSSDTFPP APWWPPGPPP TNFSSLELEP
410 420 430 440 450
RGQQPVAKAE GSPTAILIGC LVAIILLLLL IIALMLWRLH WRRLLSKAER
460 470 480 490 500
RVLEEELTVH LSVPGDTILI NNRPGPREPP PYQEPRPRGT PPHSAPCVPN
510 520 530 540 550
GSACSGDYME PEKPGAPLLP PPPQNSVPHY AEADIVTLQG VTGGNTYAVP
560 570 580 590 600
ALPPGAVGDG PPRVDFPRSR LRFKEKLGEG QFGEVHLCEV EDPQDLVSSD
610 620 630 640 650
FPISVHKGHP LLVAVKILRP DATKNARNDF LKEVKIMSRL KDPNIIRLLG
660 670 680 690 700
VCVQDDPLCM ITDYMENGDL NQFLSARQLE NKATQGLSGD TESDQGPTIS
710 720 730 740 750
YPMLLHVGAQ IASGMRYLAT LNFVHRDLAT RNCLVGENFT IKIADFGMSR
760 770 780 790 800
NLYAGDYYRV QGRAVLPIRW MAWECILMGK FTTASDVWAF GVTLWEVLML
810 820 830 840 850
CRSQPFGQLT DEQVIENAGE FFRDQGRQVY LSRPPACPQT LYELMLRCWS
860 870
REPEQRPPFA QLHRFLADDA LNTV
Length:874
Mass (Da):97,207
Last modified:May 24, 2005 - v1
Checksum:iA649B2FCE360BA5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031442 mRNA. Translation: BAC27407.1.
AK143088 mRNA. Translation: BAE25267.1.
RefSeqiNP_001185760.1. NM_001198831.1.
NP_001185762.1. NM_001198833.1.
NP_031610.1. NM_007584.2.
NP_766550.1. NM_172962.1.
XP_006523601.1. XM_006523538.3.
UniGeneiMm.5021.

Genome annotation databases

GeneIDi12305.
KEGGimmu:12305.
UCSCiuc008cii.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ544T2_MOUSE
AccessioniPrimary (citable) accession number: Q544T2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)