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Protein
Submitted name:

Ephrin B1, isoform CRA_a

Gene

Efnb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin B1, isoform CRA_aImported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Efnb1Imported
ORF Names:mCG_51675Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102708. Efnb1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei237 – 262HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501013931925 – 345Sequence analysisAdd BLAST321

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi89 ↔ 153PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiQ544L9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000031217.
ExpressionAtlasiQ544L9. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ544L9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 164Ephrin RBD (ephrin receptor-binding)InterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the ephrin family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
HOVERGENiHBG051448.
KOiK05463.
OMAiRPYEYYK.
OrthoDBiEOG091G0BPC.

Family and domain databases

CDDicd10426. Ephrin-B_Ectodomain. 1 hit.
Gene3Di2.60.40.420. 1 hit.
InterProiView protein in InterPro
IPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR034255. Ephrin-B_Ecto.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiView protein in Pfam
PF00812. Ephrin. 1 hit.
PRINTSiPR01347. EPHRIN.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002533. Ephrin. 1 hit.
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiView protein in PROSITE
PS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q544L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARPGQRWLS KWLVAMVVLT LCRLATPLAK NLEPVSWSSL NPKFLSGKGL
60 70 80 90 100
VIYPKIGDKL DIICPRAEAG RPYEYYKLYL VRPEQAAACS TVLDPNVLVT
110 120 130 140 150
CNKPHQEIRF TIKFQEFSPN YMGLEFKKYH DYYITSTSNG SLEGLENREG
160 170 180 190 200
GVCRTRTMKI VMKVGQDPNA VTPEQLTTSR PSKESDNTVK TATQAPGRGS
210 220 230 240 250
QGDSDGKHET VNQEEKSGPG AGGGGSGDSD SFFNSKVALF AAVGAGCVIF
260 270 280 290 300
LLIIIFLTVL LLKLRKRHRK HTQQRAAALS LSTLASPKGG SGTAGTEPSD
310 320 330 340
IIIPLRTTEN NYCPHYEKVS GDYGHPVYIV QEMPPQSPAN IYYKV
Length:345
Mass (Da):37,859
Last modified:May 24, 2005 - v1
Checksum:i8C96FD3DC5CBC405
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK034996 mRNA. Translation: BAC28907.1.
CH466564 Genomic DNA. Translation: EDL14195.1.
CH466564 Genomic DNA. Translation: EDL14196.1.
RefSeqiNP_034240.1. NM_010110.5.
UniGeneiMm.3374.

Genome annotation databases

GeneIDi13641.
KEGGimmu:13641.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ544L9_MOUSE
AccessioniPrimary (citable) accession number: Q544L9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation