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Protein
Submitted name:

Purinergic receptor P2Y, G-protein coupled 1

Gene

P2ry1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Purinergic receptor P2Y, G-protein coupled 1Imported
Gene namesi
Name:P2ry1Imported
ORF Names:mCG_19415Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:105049. P2ry1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 77HelicalSequence analysisAdd BLAST22
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei129 – 147HelicalSequence analysisAdd BLAST19
Transmembranei168 – 189HelicalSequence analysisAdd BLAST22
Transmembranei214 – 246HelicalSequence analysisAdd BLAST33
Transmembranei258 – 276HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000027765.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029331.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 324G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEMX. Eukaryota.
ENOG410Z2ZK. LUCA.
HOVERGENiHBG101120.
KOiK04270.
OMAiDYLRSYF.
OrthoDBiEOG091G093Y.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000142. P2Y1_rcpt.
[Graphical view]
PANTHERiPTHR24231:SF2. PTHR24231:SF2. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00595. P2Y1PRNOCPTR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q544J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEVPWSVVP NGTDAAFLAG LGSLWGNSTV ASTAAVSSSF QCALTKTGFQ
60 70 80 90 100
FYYLPAVYIL VFIIGFLGNS VAIWMFVFHM KPWSGISVYM FNLALADFLY
110 120 130 140 150
VLTLPALIFY YFNKTDWIFG DAMCKLQRFI FHVNLYGSIL FLTCISAHRY
160 170 180 190 200
SGVVYPLKSL GRLKKKNAIY VSVLVWLIVV VAISPILFYS GTGTRKNKTV
210 220 230 240 250
TCYDTTSNDY LRSYFIYSMC TTVAMFCIPL VLILGCYGLI VKALIYNDLD
260 270 280 290 300
NSPLRRKSIY LVIIVLTVFA VSYIPFHVMK TMNLRARLDF QTPEMCDFND
310 320 330 340 350
RVYATYQVTR GLASLNSCVD PILYFLAGDT FRRRLSRATR KASRRSEANL
360 370
QSKSEEMTLN ILSEFKQNGD TSL
Length:373
Mass (Da):42,213
Last modified:May 24, 2005 - v1
Checksum:i944125E9F4560BB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138634 mRNA. Translation: AAI38635.1.
BC138635 mRNA. Translation: AAI38636.1.
AK033660 mRNA. Translation: BAC28413.1.
AK036611 mRNA. Translation: BAC29506.1.
CH466530 Genomic DNA. Translation: EDL35380.1.
RefSeqiNP_001268945.1. NM_001282016.1.
NP_032798.1. NM_008772.5.
UniGeneiMm.281452.

Genome annotation databases

GeneIDi18441.
KEGGimmu:18441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138634 mRNA. Translation: AAI38635.1.
BC138635 mRNA. Translation: AAI38636.1.
AK033660 mRNA. Translation: BAC28413.1.
AK036611 mRNA. Translation: BAC29506.1.
CH466530 Genomic DNA. Translation: EDL35380.1.
RefSeqiNP_001268945.1. NM_001282016.1.
NP_032798.1. NM_008772.5.
UniGeneiMm.281452.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029331.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18441.
KEGGimmu:18441.

Organism-specific databases

CTDi5028.
MGIiMGI:105049. P2ry1.

Phylogenomic databases

eggNOGiENOG410IEMX. Eukaryota.
ENOG410Z2ZK. LUCA.
HOVERGENiHBG101120.
KOiK04270.
OMAiDYLRSYF.
OrthoDBiEOG091G093Y.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027765.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000142. P2Y1_rcpt.
[Graphical view]
PANTHERiPTHR24231:SF2. PTHR24231:SF2. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00595. P2Y1PRNOCPTR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ544J5_MOUSE
AccessioniPrimary (citable) accession number: Q544J5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.