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Protein
Submitted name:

B-cell leukemia/lymphoma 6

Gene

Bcl6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell leukemia/lymphoma 6Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Bcl6Imported
ORF Names:mCG_125078Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107187. Bcl6.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000022508.
ExpressionAtlasiQ544F9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023151.

Structurei

3D structure databases

SMRiQ544F9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 99BTB (POZ)InterPro annotationAdd BLAST68
Domaini519 – 547C2H2-typeInterPro annotationAdd BLAST29
Domaini547 – 574C2H2-typeInterPro annotationAdd BLAST28
Domaini575 – 602C2H2-typeInterPro annotationAdd BLAST28
Domaini603 – 630C2H2-typeInterPro annotationAdd BLAST28
Domaini631 – 658C2H2-typeInterPro annotationAdd BLAST28
Domaini659 – 682C2H2-typeInterPro annotationAdd BLAST24

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG004831.
KOiK15618.
OMAiNECDCRF.
OrthoDBiEOG091G025U.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiView protein in InterPro
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
PfamiView protein in Pfam
PF00651. BTB. 1 hit.
SMARTiView protein in SMART
SM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiView protein in PROSITE
PS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequencei

Sequence statusi: Complete.

Q544F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIVVSR EQFRAHKTVL
60 70 80 90 100
MACSGLFYSI FTDQLKCNLS VINLDPEISP EGFCILLDFM YTSRLNLREG
110 120 130 140 150
NIMAVMTTAM YLQMEHVVDT CRKFIKASEA EMAPALKPPR EEFLNSRMLM
160 170 180 190 200
PHDIMAYRGR EVVENNMPLR NTPGCESRAF APPLYSGLST PPASYPMYSH
210 220 230 240 250
LPLSTFLFSD EELRDAPRMP VANPFPKERA LPCDSARQVP NEYSRPAMEV
260 270 280 290 300
SPSLCHSNIY SPKEAVPEEA RSDIHYSVPE GPKPAVPSAR NAPYFPCDKA
310 320 330 340 350
SKEEERPSSE DEIALHFEPP NAPLNRKGLV SPQSPQKSDC QPNSPTESCS
360 370 380 390 400
SKNACILQAS GSPPAKSPTD PKACNWKKYK FIVLNSLNQN AKPEGSEQAE
410 420 430 440 450
LGRLSPRAYP APPACQPPME PANLDLQSPT KLSASGEDST IPQASRLNNL
460 470 480 490 500
VNRSLAGSPR SSSESHSPLY MHPPKCTSCG SQSPQHTEMC LHTAGPTFPE
510 520 530 540 550
EMGETQSEYS DSSCENGTFF CNECDCRFSE EASLKRHTLQ THSDKPYKCD
560 570 580 590 600
RCQASFRYKG NLASHKTVHT GEKPYRCNIC GAQFNRPANL KTHTRIHSGE
610 620 630 640 650
KPYKCETCGA RFVQVAHLRA HVLIHTGEKP YPCEICGTRF RHLQTLKSHL
660 670 680 690 700
RIHTGEKPYH CEKCNLHFRH KSQLRLHLRQ KHGAITNTKV QYRVSAADLP

PELPKAC
Length:707
Mass (Da):78,982
Last modified:May 24, 2005 - v1
Checksum:i2051DD808D32D5EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039228 mRNA. Translation: BAC30286.1.
AK151229 mRNA. Translation: BAE30221.1.
CH466521 Genomic DNA. Translation: EDK97676.1.
RefSeqiNP_033874.1. NM_009744.4.
XP_017172344.1. XM_017316855.1.
UniGeneiMm.347398.

Genome annotation databases

GeneIDi12053.
KEGGimmu:12053.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039228 mRNA. Translation: BAC30286.1.
AK151229 mRNA. Translation: BAE30221.1.
CH466521 Genomic DNA. Translation: EDK97676.1.
RefSeqiNP_033874.1. NM_009744.4.
XP_017172344.1. XM_017316855.1.
UniGeneiMm.347398.

3D structure databases

SMRiQ544F9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023151.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12053.
KEGGimmu:12053.

Organism-specific databases

CTDi604.
MGIiMGI:107187. Bcl6.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG004831.
KOiK15618.
OMAiNECDCRF.
OrthoDBiEOG091G025U.

Miscellaneous databases

ChiTaRSiBcl6. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022508.
ExpressionAtlasiQ544F9. baseline and differential.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiView protein in InterPro
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
PfamiView protein in Pfam
PF00651. BTB. 1 hit.
SMARTiView protein in SMART
SM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiView protein in PROSITE
PS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ544F9_MOUSE
AccessioniPrimary (citable) accession number: Q544F9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 15, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.