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Protein
Submitted name:

Interleukin 17A

Gene

Il17a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 17AImported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Il17aImported
Synonyms:Il17Imported
ORF Names:mCG_7914Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107364. Il17a.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501013931526 – 158Sequence analysisAdd BLAST133

Expressioni

Gene expression databases

BgeeiENSMUSG00000025929.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027061.

Structurei

3D structure databases

SMRiQ544E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J12P. Eukaryota.
ENOG410YS4N. LUCA.
HOVERGENiHBG006143.
KOiK05489.
OMAiHMNSVPI.
OrthoDBiEOG091G0RG1.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR020440. IL-17_chr.
IPR010345. IL-17_fam.
PfamiView protein in Pfam
PF06083. IL17. 1 hit.
PRINTSiPR01932. INTRLEUKIN17.
SUPFAMiSSF57501. SSF57501. 1 hit.

Sequencei

Sequence statusi: Complete.

Q544E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPGRASSVS LMLLLLLSLA ATVKAAAIIP QSSACPNTEA KDFLQNVKVN
60 70 80 90 100
LKVFNSLGAK VSSRRPSDYL NRSTSPWTLH RNEDPDRYPS VIWEAQCRHQ
110 120 130 140 150
RCVNAEGKLD HHMNSVLIQQ EILVLKREPE SCPFTFRVEK MLVGVGCTCV

ASIVRQAA
Length:158
Mass (Da):17,490
Last modified:May 24, 2005 - v1
Checksum:i3505C143435F4653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119303 mRNA. Translation: AAI19304.1.
BC119309 mRNA. Translation: AAI19310.1.
AK040420 mRNA. Translation: BAC30590.1.
CH466536 Genomic DNA. Translation: EDL14378.1.
RefSeqiNP_034682.1. NM_010552.3.
UniGeneiMm.5419.

Genome annotation databases

GeneIDi16171.
KEGGimmu:16171.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119303 mRNA. Translation: AAI19304.1.
BC119309 mRNA. Translation: AAI19310.1.
AK040420 mRNA. Translation: BAC30590.1.
CH466536 Genomic DNA. Translation: EDL14378.1.
RefSeqiNP_034682.1. NM_010552.3.
UniGeneiMm.5419.

3D structure databases

SMRiQ544E6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027061.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi16171.
KEGGimmu:16171.

Organism-specific databases

CTDi3605.
MGIiMGI:107364. Il17a.

Phylogenomic databases

eggNOGiENOG410J12P. Eukaryota.
ENOG410YS4N. LUCA.
HOVERGENiHBG006143.
KOiK05489.
OMAiHMNSVPI.
OrthoDBiEOG091G0RG1.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000025929.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiView protein in InterPro
IPR029034. Cystine-knot_cytokine.
IPR020440. IL-17_chr.
IPR010345. IL-17_fam.
PfamiView protein in Pfam
PF06083. IL17. 1 hit.
PRINTSiPR01932. INTRLEUKIN17.
SUPFAMiSSF57501. SSF57501. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ544E6_MOUSE
AccessioniPrimary (citable) accession number: Q544E6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 7, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.