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Protein

Beta-lactamase

Gene

sme-2

Organism
Serratia marcescens
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
Biological processAntibiotic resistanceSAAS annotation

Protein family/group databases

MEROPSiS11.A01.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseSAAS annotation (EC:3.5.2.6SAAS annotation)
Gene namesi
Name:sme-2Imported
Synonyms:blaSME-1Imported, blaSME-4Imported, blaSME1Imported
ORF Names:B7L73_15195Imported, SME12620_22Imported
OrganismiSerratia marcescensImported
Taxonomic identifieri615 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000193239 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501084400628 – 294Beta-lactamaseSequence analysisAdd BLAST267

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi72 ↔ 242Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DY6X-ray2.13A/B28-294[»]
SMRiQ54488.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK19316.

Family and domain databases

InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A.
PRINTSiPR00118. BLACTAMASEA.
SUPFAMiSSF56601. SSF56601. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54488-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNKVNFKTA SFLFSVCLAL SAFNAHANKS DAAAKQIKKL EEDFDGRIGV
60 70 80 90 100
FAIDTGSGNT FGYRSDERFP LCSSFKGFLA AAVLERVQQK KLDINQKVKY
110 120 130 140 150
ESRDLEYHSP ITTKYKGSGM TLGDMASAAL QYSDNGATNI IMERFLGGPE
160 170 180 190 200
GMTKFMRSIG DNEFRLDRWE LELNTAIPGD KRDTSTPKAV ANSLNKLALG
210 220 230 240 250
NVLNAKVKAI YQNWLKGNTT GDARIRASVP ADWVVGDKTG SCGAYGTAND
260 270 280 290
YAVIWPKNRA PLIVSIYTTR KSKDDKHSDK TIAEASRIAI QAID
Length:294
Mass (Da):32,247
Last modified:November 1, 1996 - v1
Checksum:iC326C0DC65293094
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60295 Genomic DNA. Translation: AAB03414.1.
JF974075 Genomic DNA. Translation: AEJ79644.1.
KF615855 Genomic DNA. Translation: AGZ03855.1.
KF481967 Genomic DNA. Translation: AHA49908.1.
NBWX01000005 Genomic DNA. Translation: OSB81787.1.
RefSeqiWP_063864730.1. NZ_NGUD01000001.1.

Genome annotation databases

KEGGiag:AHA49908.
PATRICifig|615.109.peg.3851.

Similar proteinsi

Entry informationi

Entry nameiQ54488_SERMA
AccessioniPrimary (citable) accession number: Q54488
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported