Q54413 (Q54413_STRLI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acetyl-xylan esterase EMBL AAC06115.2

Gene names

Name:

axeA EMBL AAC06115.2

Organism

Streptomyces lividans EMBL AAC06115.2

Taxonomic identifier

1916 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Signal EMBL AAC06115.2
Ligand	Metal-binding PDB 2CC0 Zinc PDB 2CC0
Technical term	3D-structure PDB 2CC0
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW polysaccharide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 41	41	Potential EMBL AAC06115.2
	Chain	42 – 335	294	Potential EMBL AAC06115.2		PRO_5000143455
Sites
	Metal binding	54	1	Zinc PDB 2CC0
	Metal binding	103	1	Zinc; via tele nitrogen PDB 2CC0
	Metal binding	107	1	Zinc; via tele nitrogen PDB 2CC0

Sequences

	Sequence		Length	Mass (Da)
	Q54413 [UniParc]. Last modified June 1, 2003. Version 3. Checksum: 04A160CC8FE71A21	FASTA	335	34,155
	10 20 30 40 50 60 MRTSTGPRAS SRTLRTLASG VAVTALAAAG TVAAGAAPAQ AAACNGYVGL TFDDGPSGST 70 80 90 100 110 120 QSLLNALRQN GLRATMFNQG QYAAQNPSLV RAQVDAGMWV ANHSYTHPHM TQLGQAQMDS 130 140 150 160 170 180 EISRTQQAIA GAGGGTPKLF RPPYGETNAT LRSVEAKYGL TEVIWDVDSQ DWNNASTDAI 190 200 210 220 230 240 VQAVSRLGNG QVILMHDWPA NTLAAIPRIA QTLAGKGLCS GMISPQTGRA VAPDGSGGGG 250 260 270 280 290 300 DGGGGGGGAC TATLSAGQRW GDRYNLNVSV SGASDWTVTM NVPSPAKVLS TWNVNASYPS 310 320 330 AQTLTAKSNG SGGNWGATIQ ANGNWTWPSV SCTAG

References

[1]	"Sequences of three genes specifying xylanases in Streptomyces lividans." Shareck F., Roy C., Yaguchi M., Morosoli R., Kluepfel D. Gene 107:75-82(1991) [PubMed: 1743521] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 1326 EMBL AAC06115.2.
[2]	"Analysis of DNA flanking the xlnB locus of Streptomyces lividans reveals genes encoding acetyl xylan esterase and the RNA component of ribonuclease P." Shareck F., Biely P., Morosoli R., Kluepfel D. Gene 153:105-109(1995) [PubMed: 7533741] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 1326 EMBL AAC06115.2.
[3]	Shareck F. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 1326 EMBL AAC06115.2.
[4]	"Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases." Taylor E.J., Gloster T.M., Turkenburg J.P., Vincent F., Brzozowski A.M., Dupont C., Shareck F., Centeno M.S., Prates J.A., Puchart V., Ferreira L.M., Fontes C.M., Biely P., Davies G.J. J. Biol. Chem. 281:10968-10975(2006) [PubMed: 16431911] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 42-236 IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M64552 Genomic DNA. Translation: AAC06115.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2CC0	X-ray	1.60	A/B	42-236	[»]

ProteinModelPortal

Q54413.

SMR

Q54413. Positions 43-234.

ModBase

Search...

Protein family/group databases

CAZy

CBM2. Carbohydrate-Binding Module Family 2.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR008965. Carb-bd_dom.
IPR012291. CBD_carb-bd_dom.
IPR001919. Cellulose-bd_dom_fam2_bac.
IPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR002509. Polysac_deacetylase.
[Graphical view]

Gene3D

G3DSA:2.60.40.290. CBD_carb_bd. 1 hit.
G3DSA:3.20.20.370. Polysac_deacetylase. 1 hit.

Pfam

PF01522. Polysacc_deac_1. 1 hit.
[Graphical view]

SMART

SM00637. CBD_II. 1 hit.
[Graphical view]

SUPFAM

SSF49384. Cellul_bind. 1 hit.
SSF88713. Glyco_hydro/deAcase_b/a-brl. 1 hit.

PROSITE

PS51173. CBM2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q54413_STRLI

Accession

Primary (citable) accession number: Q54413

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 58 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)