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Protein
Submitted name:

5-hydroxytryptamine (Serotonin) receptor 1F

Gene

Htr1f

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine (Serotonin) receptor 1FImported
Gene namesi
Name:Htr1fImported
ORF Names:mCG_128761Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99842. Htr1f.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 50HelicalSequence analysisAdd BLAST27
Transmembranei62 – 86HelicalSequence analysisAdd BLAST25
Transmembranei98 – 119HelicalSequence analysisAdd BLAST22
Transmembranei140 – 161HelicalSequence analysisAdd BLAST22
Transmembranei181 – 202HelicalSequence analysisAdd BLAST22
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Transmembranei331 – 350HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000050783.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 347G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST308

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106962.
KOiK04153.
OMAiNVCEKCK.
OrthoDBiEOG091G06VI.

Family and domain databases

CDDicd15334. 7tmA_5-HT1F. 1 hit.
InterProiView protein in InterPro
IPR000450. 5HT1F_rcpt.
IPR002231. 5HT_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24247:SF156. PTHR24247:SF156. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01101. 5HTRECEPTOR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q543V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLNASDQN LTSEELLNRM PSKILVSLTL SGLALMTTTI NSLVIAAIIV
60 70 80 90 100
TRKLHHPANY LICSLAVTDF LVAVLVMPFS IVYIVRESWI MGQVLCDIWL
110 120 130 140 150
SVDIICCTCS ILHLSAIALD RYRAITDAVE YARKRTPRHA GIMITIVWVI
160 170 180 190 200
SVFISMPPLF WRHQGTSRDD ECVIKHDHIV STIYSTFGAF YIPLVLILIL
210 220 230 240 250
YYKIYRAART LYHKRQASRM IKEELNGQVF LESGEKSIKL VSTSYMLEKS
260 270 280 290 300
LSDPSTDFDR IHSTVKSPRS ELKHEKSWRR QKISGTRERK AATTLGLILG
310 320 330 340 350
AFVICWLPFF VKELVVNVCE KCKISEEMSN FLAWLGYLNS LINPLIYTIF
360
NEDFKKAFQK LVRCRY
Length:366
Mass (Da):41,977
Last modified:May 24, 2005 - v1
Checksum:i69EC1CD6F22BD93F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120507 mRNA. Translation: AAI20508.1.
BC137604 mRNA. Translation: AAI37605.1.
AK045364 mRNA. Translation: BAC32328.1.
CH466521 Genomic DNA. Translation: EDK98243.1.
RefSeqiNP_032336.1. NM_008310.3.
UniGeneiMm.5040.

Genome annotation databases

GeneIDi15557.
KEGGimmu:15557.

Similar proteinsi

Entry informationi

Entry nameiQ543V2_MOUSE
AccessioniPrimary (citable) accession number: Q543V2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: August 30, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)