Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

5-hydroxytryptamine (Serotonin) receptor 1F

Gene

Htr1f

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
5-hydroxytryptamine (Serotonin) receptor 1FImported
Gene namesi
Name:Htr1fImported
ORF Names:mCG_128761Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99842. Htr1f.

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 50HelicalSequence analysisAdd BLAST27
Transmembranei62 – 86HelicalSequence analysisAdd BLAST25
Transmembranei98 – 119HelicalSequence analysisAdd BLAST22
Transmembranei140 – 161HelicalSequence analysisAdd BLAST22
Transmembranei181 – 202HelicalSequence analysisAdd BLAST22
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Transmembranei331 – 350HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000050783.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063136.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 347G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST308

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106962.
KOiK04153.
OMAiTPYMLEK.
OrthoDBiEOG091G06VI.

Family and domain databases

InterProiIPR000450. 5HT1F_rcpt.
IPR002231. 5HT_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24247:SF34. PTHR24247:SF34. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00515. 5HT1FRECEPTR.
PR01101. 5HTRECEPTOR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q543V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFLNASDQN LTSEELLNRM PSKILVSLTL SGLALMTTTI NSLVIAAIIV
60 70 80 90 100
TRKLHHPANY LICSLAVTDF LVAVLVMPFS IVYIVRESWI MGQVLCDIWL
110 120 130 140 150
SVDIICCTCS ILHLSAIALD RYRAITDAVE YARKRTPRHA GIMITIVWVI
160 170 180 190 200
SVFISMPPLF WRHQGTSRDD ECVIKHDHIV STIYSTFGAF YIPLVLILIL
210 220 230 240 250
YYKIYRAART LYHKRQASRM IKEELNGQVF LESGEKSIKL VSTSYMLEKS
260 270 280 290 300
LSDPSTDFDR IHSTVKSPRS ELKHEKSWRR QKISGTRERK AATTLGLILG
310 320 330 340 350
AFVICWLPFF VKELVVNVCE KCKISEEMSN FLAWLGYLNS LINPLIYTIF
360
NEDFKKAFQK LVRCRY
Length:366
Mass (Da):41,977
Last modified:May 24, 2005 - v1
Checksum:i69EC1CD6F22BD93F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120507 mRNA. Translation: AAI20508.1.
BC137604 mRNA. Translation: AAI37605.1.
AK045364 mRNA. Translation: BAC32328.1.
CH466521 Genomic DNA. Translation: EDK98243.1.
RefSeqiNP_032336.1. NM_008310.3.
UniGeneiMm.5040.

Genome annotation databases

GeneIDi15557.
KEGGimmu:15557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120507 mRNA. Translation: AAI20508.1.
BC137604 mRNA. Translation: AAI37605.1.
AK045364 mRNA. Translation: BAC32328.1.
CH466521 Genomic DNA. Translation: EDK98243.1.
RefSeqiNP_032336.1. NM_008310.3.
UniGeneiMm.5040.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063136.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15557.
KEGGimmu:15557.

Organism-specific databases

CTDi3355.
MGIiMGI:99842. Htr1f.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106962.
KOiK04153.
OMAiTPYMLEK.
OrthoDBiEOG091G06VI.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000050783.

Family and domain databases

InterProiIPR000450. 5HT1F_rcpt.
IPR002231. 5HT_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24247:SF34. PTHR24247:SF34. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00515. 5HT1FRECEPTR.
PR01101. 5HTRECEPTOR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ543V2_MOUSE
AccessioniPrimary (citable) accession number: Q543V2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.