Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Prostaglandin-endoperoxide synthase 1

Gene

Ptgs1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin-endoperoxide synthase 1Imported
Submitted name:
Ptgs1 proteinImported
Gene namesi
Name:Ptgs1Imported
ORF Names:mCG_22272Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97797. Ptgs1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500878078028 – 602Sequence analysisAdd BLAST575

Expressioni

Gene expression databases

BgeeiENSMUSG00000047250.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059977.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 72EGF-likeInterPro annotationAdd BLAST39

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408. Eukaryota.
ENOG410XPZ3. LUCA.
HOVERGENiHBG000366.
KOiK00509.
OMAiFKTSGKM.
OrthoDBiEOG091G03CD.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029580. COX-1.
IPR000742. EGF-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF6. PTHR11903:SF6. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q543T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRSLSLWF PLLLLLLLPP TPSVLLADPG VPSPVNPCCY YPCQNQGVCV
60 70 80 90 100
RFGLDNYQCD CTRTGYSGPN CTIPEIWTWL RNSLRPSPSF THFLLTHGYW
110 120 130 140 150
LWEFVNATFI REVLMRLVLT VRSNLIPSPP TYNSAHDYIS WESFSNVSYY
160 170 180 190 200
TRILPSVPKD CPTPMGTKGK KQLPDVQLLA QQLLLRREFI PAPQGTNILF
210 220 230 240 250
AFFAQHFTHQ FFKTSGKMGP GFTKALGHGV DLGHIYGDNL ERQYHLRLFK
260 270 280 290 300
DGKLKYQVLD GEVYPPSVEQ ASVLMRYPPG VPPERQMAVG QEVFGLLPGL
310 320 330 340 350
MLFSTIWLRE HNRVCDLLKE EHPTWDDEQL FQTTRLILIG ETIKIVIEEY
360 370 380 390 400
VQHLSGYFLQ LKFDPELLFR AQFQYRNRIA MEFNHLYHWH PLMPNSFQVG
410 420 430 440 450
SQEYSYEQFL FNTSMLVDYG VEALVDAFSR QRAGRIGGGR NFDYHVLHVA
460 470 480 490 500
VDVIKESREM RLQPFNEYRK RFGLKPYTSF QELTGEKEMA AELEELYGDI
510 520 530 540 550
DALEFYPGLL LEKCQPNSIF GESMIEMGAP FSLKGLLGNP ICSPEYWKPS
560 570 580 590 600
TFGGDVGFNL VNTASLKKLV CLNTKTCPYV SFRVPDYPGD DGSVLVRRST

EL
Length:602
Mass (Da):69,042
Last modified:May 24, 2005 - v1
Checksum:i634C0E602045C3A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023322 mRNA. Translation: AAH23322.2.
AH015269
, DQ173708, DQ173710, DQ173711, DQ173712, DQ173713, DQ173714 Genomic DNA. Translation: ABA19088.1.
AH015270
, DQ173699, DQ173700, DQ173701, DQ173702, DQ173703, DQ173704 Genomic DNA. Translation: ABA19089.1.
AK046457 mRNA. Translation: BAC32737.1.
AK138432 mRNA. Translation: BAE23660.1.
AK142741 mRNA. Translation: BAE25179.1.
AK159907 mRNA. Translation: BAE35471.1.
AK163609 mRNA. Translation: BAE37419.1.
AK170414 mRNA. Translation: BAE41780.1.
AK170664 mRNA. Translation: BAE41945.1.
CT010314 mRNA. Translation: CAJ18522.1.
CH466542 Genomic DNA. Translation: EDL08676.1.
RefSeqiNP_032995.1. NM_008969.4.
XP_006497853.1. XM_006497790.3.
XP_006497854.1. XM_006497791.3.
XP_011237338.1. XM_011239036.2.
XP_017171985.1. XM_017316496.1.
UniGeneiMm.275434.

Genome annotation databases

GeneIDi19224.
KEGGimmu:19224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023322 mRNA. Translation: AAH23322.2.
AH015269
, DQ173708, DQ173710, DQ173711, DQ173712, DQ173713, DQ173714 Genomic DNA. Translation: ABA19088.1.
AH015270
, DQ173699, DQ173700, DQ173701, DQ173702, DQ173703, DQ173704 Genomic DNA. Translation: ABA19089.1.
AK046457 mRNA. Translation: BAC32737.1.
AK138432 mRNA. Translation: BAE23660.1.
AK142741 mRNA. Translation: BAE25179.1.
AK159907 mRNA. Translation: BAE35471.1.
AK163609 mRNA. Translation: BAE37419.1.
AK170414 mRNA. Translation: BAE41780.1.
AK170664 mRNA. Translation: BAE41945.1.
CT010314 mRNA. Translation: CAJ18522.1.
CH466542 Genomic DNA. Translation: EDL08676.1.
RefSeqiNP_032995.1. NM_008969.4.
XP_006497853.1. XM_006497790.3.
XP_006497854.1. XM_006497791.3.
XP_011237338.1. XM_011239036.2.
XP_017171985.1. XM_017316496.1.
UniGeneiMm.275434.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059977.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi19224.
KEGGimmu:19224.

Organism-specific databases

CTDi5742.
MGIiMGI:97797. Ptgs1.

Phylogenomic databases

eggNOGiKOG2408. Eukaryota.
ENOG410XPZ3. LUCA.
HOVERGENiHBG000366.
KOiK00509.
OMAiFKTSGKM.
OrthoDBiEOG091G03CD.

Miscellaneous databases

ChiTaRSiPtgs1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047250.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029580. COX-1.
IPR000742. EGF-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF6. PTHR11903:SF6. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ543T1_MOUSE
AccessioniPrimary (citable) accession number: Q543T1
Secondary accession number(s): Q8CIL6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.