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Q543T0

- Q543T0_MOUSE

UniProt

Q543T0 - Q543T0_MOUSE

Protein
Submitted name:

Somatostatin receptor 1

Gene

Sstr1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. somatostatin receptor activity Source: MGI

    GO - Biological processi

    1. cellular response to estradiol stimulus Source: Ensembl
    2. cerebellum development Source: Ensembl
    3. forebrain development Source: Ensembl
    4. glutamate receptor signaling pathway Source: MGI
    5. G-protein coupled receptor signaling pathway Source: MGI
    6. neuropeptide signaling pathway Source: MGI
    7. response to starvation Source: Ensembl
    8. spermatogenesis Source: Ensembl

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Somatostatin receptor 1Imported
    Gene namesi
    Name:Sstr1Imported
    ORF Names:mCG_22882Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:98327. Sstr1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. integral component of membrane Source: UniProtKB-KW
    3. membrane Source: MGI
    4. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ543T0.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00630000089736.
    HOVERGENiHBG106919.
    InParanoidiQ543T0.
    KOiK04217.
    OMAiLLHHWPF.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000586. Somatstn_rcpt.
    IPR001116. Somatstn_rcpt_1.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00246. SOMATOSTATNR.
    PR00587. SOMATOSTTN1R.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q543T0-1 [UniParc]FASTAAdd to Basket

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    MFPNGTASSP SSSPSPSPGS CGEGACSRGP GSGAADGMEE PGRNASQNGT    50
    LSEGQGSAIL ISFIYSVVCL VGLCGNSMVI YVILRYAKMK TATNIYILNL 100
    AIADELLMLS VPFLVTSTLL RHWPFGALLC RLVLSVDAVN MFTSIYCLTV 150
    LSVDRYVAVV HPIKAARYRR PTVAKVVNLG VWVLSLLVIL PIVVFSRTAA 200
    NSDGTVACNM LMPEPAQRWL VGFVLYTFLM GFLLPVGAIC LCYVLIIAKM 250
    RMVALKAGWQ QRKRSERKIT LMVMMVVMVF VICWMPFYVV QLVNVFAEQD 300
    DATVSQLSVI LGYANSCANP ILYGFLSDNF KRSFQRILCL SWMDNAAEEP 350
    VDYYATALKS RAYSVEDFQP ENLESGGVFR NGTCASRIST L 391
    Length:391
    Mass (Da):42,718
    Last modified:May 24, 2005 - v1
    Checksum:i4461673956F2BD22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK046464 mRNA. Translation: BAC32742.1.
    CH466526 Genomic DNA. Translation: EDL36694.1.
    RefSeqiNP_033242.1. NM_009216.3.
    XP_006515697.1. XM_006515634.1.
    UniGeneiMm.278336.

    Genome annotation databases

    GeneIDi20605.
    KEGGimmu:20605.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK046464 mRNA. Translation: BAC32742.1 .
    CH466526 Genomic DNA. Translation: EDL36694.1 .
    RefSeqi NP_033242.1. NM_009216.3.
    XP_006515697.1. XM_006515634.1.
    UniGenei Mm.278336.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    DNASUi 20605.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 20605.
    KEGGi mmu:20605.

    Organism-specific databases

    CTDi 6751.
    MGIi MGI:98327. Sstr1.

    Phylogenomic databases

    GeneTreei ENSGT00630000089736.
    HOVERGENi HBG106919.
    InParanoidi Q543T0.
    KOi K04217.
    OMAi LLHHWPF.

    Miscellaneous databases

    NextBioi 298945.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q543T0.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000586. Somatstn_rcpt.
    IPR001116. Somatstn_rcpt_1.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00246. SOMATOSTATNR.
    PR00587. SOMATOSTTN1R.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Corpora quadrigeminaImported.
    10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.

    Entry informationi

    Entry nameiQ543T0_MOUSE
    AccessioniPrimary (citable) accession number: Q543T0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)