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Protein
Submitted name:

Chemokine (C-C motif) receptor 2

Gene

Ccr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-C motif) receptor 2Imported
Gene namesi
Name:Ccr2Imported
ORF Names:mCG_16379Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106185. Ccr2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei93 – 112HelicalSequence analysisAdd BLAST20
Transmembranei132 – 154HelicalSequence analysisAdd BLAST23
Transmembranei166 – 191HelicalSequence analysisAdd BLAST26
Transmembranei221 – 243HelicalSequence analysisAdd BLAST23
Transmembranei255 – 278HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiQ543S8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000049103.

Structurei

3D structure databases

SMRiQ543S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 318G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST247

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106917.
KOiK04177.
OMAiCPVFYRE.
OrthoDBiEOG091G0B7A.

Family and domain databases

InterProiView protein in InterPro
IPR002237. Chemokine_CCR2.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00657. CCCHEMOKINER.
PR01107. CHEMOKINER2.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q543S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDNNMLPQF IHGILSTSHS LFTRSIQELD EGATTPYDYD DGEPCHKTSV
60 70 80 90 100
KQIGAWILPP LYSLVFIFGF VGNMLVIIIL IGCKKLKSMT DIYLLNLAIS
110 120 130 140 150
DLLFLLTLPF WAHYAANEWV FGNIMCKVFT GLYHIGYFGG IFFIILLTID
160 170 180 190 200
RYLAIVHAVF ALKARTVTFG VITSVVTWVV AVFASLPGII FTKSKQDDHH
210 220 230 240 250
YTCGPYFTQL WKNFQTIMRN ILSLILPLLV MVICYSGILH TLFRCRNEKK
260 270 280 290 300
RHRAVRLIFA IMIVYFLFWT PYNIVLFLTT FQESLGMSNC VIDKHLDQAM
310 320 330 340 350
QVTETLGMTH CCINPVIYAF VGEKFRRYLS IFFRKHIAKR LCKQCPVFYR
360 370
ETADRVSSTF TPSTGEQEVS VGL
Length:373
Mass (Da):42,783
Last modified:May 24, 2005 - v1
Checksum:iFA012C10F4C9325A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138803 mRNA. Translation: AAI38804.1.
BC138804 mRNA. Translation: AAI38805.1.
AK046579 mRNA. Translation: BAC32793.1.
AK138599 mRNA. Translation: BAE23710.1.
CH466671 Genomic DNA. Translation: EDL37176.1.
RefSeqiNP_034045.1. NM_009915.2.
XP_006512491.1. XM_006512428.2.
XP_011241365.1. XM_011243063.1.
XP_011241366.1. XM_011243064.2.
UniGeneiMm.6272.

Genome annotation databases

GeneIDi12772.
KEGGimmu:12772.

Similar proteinsi

Entry informationi

Entry nameiQ543S8_MOUSE
AccessioniPrimary (citable) accession number: Q543S8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)