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Protein
Submitted name:

Serine (Or cysteine) peptidase inhibitor, clade E, member 2, isoform CRA_b

Gene

Serpine2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade E, member 2, isoform CRA_bImported
Gene namesi
Name:Serpine2Imported
ORF Names:mCG_21670Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:101780. Serpine2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 397377Sequence analysisPRO_5007923989Add
BLAST

Expressioni

Gene expression databases

BgeeiENSMUSG00000026249.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027467.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 397362SERPINInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00840000129734.
HOVERGENiHBG106493.
KOiK16643.
OMAiNDLWYNF.
OrthoDBiEOG091G0ION.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q543R5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNWHFPFFIL TTVTLYSVHS QFNSLSLEEL GSNTGIQVFN QIIKSRPHEN
60 70 80 90 100
VVVSPHGIAS ILGMLQLGAD GKTKKQLSTV MRYNVNGVGK VLKKINKAIV
110 120 130 140 150
SKKNKDIVTV ANAVFLRNGF KMEVPFAVRN KDVFQCEVQN VNFQDPASAS
160 170 180 190 200
ESINFWVKNE TRGMIDNLLS PNLIDGALTR LVLVNAVYFK GLWKSRFQPE
210 220 230 240 250
STKKRTFVAG DGKSYQVPML AQLSVFRSGS TRTPNGLWYN FIELPYHGES
260 270 280 290 300
ISMLIALPTE SSTPLSAIIP HITTKTIDSW MNTMVPKRMQ LVLPKFTAVA
310 320 330 340 350
QTDLKEPLKA LGITEMFEPS KANFTKITRS ESLHVSHILQ KAKIEVSEDG
360 370 380 390
TKASAATTAI LIARSSPPWF IVDRPFLFSI RHNPTGAILF LGQVNKP
Length:397
Mass (Da):44,207
Last modified:May 24, 2005 - v1
Checksum:iB8EBAE3CA899D4A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045954 mRNA. Translation: BAC32546.1.
AK047856 mRNA. Translation: BAC33176.1.
AK051332 mRNA. Translation: BAC34605.1.
CH466687 Genomic DNA. Translation: EDL16268.1.
RefSeqiNP_033281.1. NM_009255.4.
XP_006496522.1. XM_006496459.2.
XP_006496523.1. XM_006496460.2.
UniGeneiMm.3093.

Genome annotation databases

GeneIDi20720.
KEGGimmu:20720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045954 mRNA. Translation: BAC32546.1.
AK047856 mRNA. Translation: BAC33176.1.
AK051332 mRNA. Translation: BAC34605.1.
CH466687 Genomic DNA. Translation: EDL16268.1.
RefSeqiNP_033281.1. NM_009255.4.
XP_006496522.1. XM_006496459.2.
XP_006496523.1. XM_006496460.2.
UniGeneiMm.3093.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027467.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20720.
KEGGimmu:20720.

Organism-specific databases

CTDi5270.
MGIiMGI:101780. Serpine2.

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00840000129734.
HOVERGENiHBG106493.
KOiK16643.
OMAiNDLWYNF.
OrthoDBiEOG091G0ION.

Miscellaneous databases

ChiTaRSiSerpine2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026249.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ543R5_MOUSE
AccessioniPrimary (citable) accession number: Q543R5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.