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Protein
Submitted name:

Antithrombin

Gene

Serpinc1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
AntithrombinImported
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade C (Antithrombin), member 1Imported
Gene namesi
Name:Serpinc1Imported
Synonyms:AT3Imported
ORF Names:mCG_9405Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88095. Serpinc1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 34Sequence analysisAdd BLAST34
ChainiPRO_501109937935 – 465Sequence analysisAdd BLAST431

Expressioni

Gene expression databases

BgeeiENSMUSG00000026715.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 462SERPINInterPro annotationAdd BLAST370

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
HOVERGENiHBG005957.
KOiK03911.
OMAiKFRYRRV.
OrthoDBiEOG091G0ION.

Family and domain databases

CDDicd02045. antithrombin-III_like. 1 hit.
InterProiView protein in InterPro
IPR033829. Antithrombin_domain.
IPR015555. AT-III.
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
IPR036186. Serpin_sf.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PTHR11461:SF53. PTHR11461:SF53. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q543J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSPGAGSGA AGERKLCLLS LLLIGALGCA ICHGNPVDDI CIAKPRDIPV
60 70 80 90 100
NPLCIYRSPG KKATEEDGSE QKVPEATNRR VWELSKANSR FATNFYQHLA
110 120 130 140 150
DSKNDNDNIF LSPLSISTAF AMTKLGACND TLKQLMEVFK FDTISEKTSD
160 170 180 190 200
QIHFFFAKLN CRLYRKANKS SDLVSANRLF GDKSLTFNES YQDVSEVVYG
210 220 230 240 250
AKLQPLDFKE NPEQSRVTIN NWVANKTEGR IKDVIPQGAI NELTALVLVN
260 270 280 290 300
TIYFKGLWKS KFSPENTRKE PFYKVDGQSC PVPMMYQEGK FKYRRVAEGT
310 320 330 340 350
QVLELPFKGD DITMVLILPK PEKSLAKVEQ ELTPELLQEW LDELSETMLV
360 370 380 390 400
VHMPRFRTED GFSLKEQLQD MGLIDLFSPE KSQLPGIVAG GRDDLYVSDA
410 420 430 440 450
FHKAFLEVNE EGSEAAASTS VVITGRSLNP NRVTFKANRP FLVLIREVAL
460
NTIIFMGRVA NPCVN
Length:465
Mass (Da):52,004
Last modified:May 24, 2005 - v1
Checksum:i5CE087E98874E35D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043785 Genomic DNA. Translation: BAB16827.1.
AK050295 mRNA. Translation: BAC34171.1.
CH466520 Genomic DNA. Translation: EDL39328.1.
RefSeqiNP_543120.1. NM_080844.4.
XP_006496689.1. XM_006496626.2.
UniGeneiMm.260770.

Genome annotation databases

GeneIDi11905.
KEGGimmu:11905.

Similar proteinsi

Entry informationi

Entry nameiQ543J5_MOUSE
AccessioniPrimary (citable) accession number: Q543J5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)