Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q54318

- HLYC_BRAHO

UniProt

Q54318 - HLYC_BRAHO

Protein

Hemolysin C

Gene

tlyC

Organism
Brachyspira hyodysenteriae (Treponema hyodysenteriae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.

    GO - Molecular functioni

    1. adenyl nucleotide binding Source: InterPro
    2. flavin adenine dinucleotide binding Source: InterPro
    3. oxidoreductase activity, acting on CH-OH group of donors Source: InterPro

    GO - Biological processi

    1. hemolysis in other organism Source: UniProtKB-KW

    Keywords - Molecular functioni

    Toxin

    Keywords - Biological processi

    Cytolysis, Hemolysis

    Protein family/group databases

    TCDBi9.A.40.1.1. the hlyc/corc (hcc) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hemolysin C
    Gene namesi
    Name:tlyC
    OrganismiBrachyspira hyodysenteriae (Treponema hyodysenteriae)
    Taxonomic identifieri159 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBrachyspiraceaeBrachyspira

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 268268Hemolysin CPRO_0000088354Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ54318.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini52 – 11160CBS 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini114 – 17158CBS 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UPF0053 family.Curated
    Contains 2 CBS domains.PROSITE-ProRule annotation

    Keywords - Domaini

    CBS domain, Repeat

    Family and domain databases

    Gene3Di3.30.465.10. 1 hit.
    InterProiIPR000644. CBS_dom.
    IPR016169. CO_DH_flavot_FAD-bd_sub2.
    IPR016166. FAD-bd_2.
    IPR005170. Transptr-assoc_dom.
    [Graphical view]
    PfamiPF00571. CBS. 2 hits.
    PF03471. CorC_HlyC. 1 hit.
    [Graphical view]
    SMARTiSM00116. CBS. 2 hits.
    SM01091. CorC_HlyC. 1 hit.
    [Graphical view]
    SUPFAMiSSF56176. SSF56176. 1 hit.
    PROSITEiPS51371. CBS. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54318-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPIKKLISKI VKKKDSDTEK NNYINLSALT EAEREIITNT IELKSKSVRE    50
    IMVPRVDVVM IPMESSYDKV IKAFNRDRNS RIPVYKDGID DIVGVLYVKD 100
    LIDAEEKNFS LKKILHKPLF VPISISLMEL LKNFREKQIH IAMVVDEYGG 150
    FSGIVSMEDV LEQIIGDIRD EYDEEDEEIK SNDDGTYLVD ARTRIDDFNK 200
    YEILPPIPDD EADTVGGFLF SYLGRLPKRN EDIEYNGYSF TVVGKSGNIV 250
    TKIRIEKLKK DNTAKNKD 268
    Length:268
    Mass (Da):30,764
    Last modified:November 1, 1996 - v1
    Checksum:iE56A3D43D8764FDA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X73141 Genomic DNA. Translation: CAA51657.1.
    PIRiT46749.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X73141 Genomic DNA. Translation: CAA51657.1 .
    PIRi T46749.

    3D structure databases

    ProteinModelPortali Q54318.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 9.A.40.1.1. the hlyc/corc (hcc) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.30.465.10. 1 hit.
    InterProi IPR000644. CBS_dom.
    IPR016169. CO_DH_flavot_FAD-bd_sub2.
    IPR016166. FAD-bd_2.
    IPR005170. Transptr-assoc_dom.
    [Graphical view ]
    Pfami PF00571. CBS. 2 hits.
    PF03471. CorC_HlyC. 1 hit.
    [Graphical view ]
    SMARTi SM00116. CBS. 2 hits.
    SM01091. CorC_HlyC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56176. SSF56176. 1 hit.
    PROSITEi PS51371. CBS. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of three putative Serpulina hyodysenteriae hemolysins."
      Ter Huurne A.A.H.M., Muir S., van Houten M., van der Zeijst B.A.M., Gaastra W., Kusters J.G.
      Microb. Pathog. 16:269-282(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: B204.

    Entry informationi

    Entry nameiHLYC_BRAHO
    AccessioniPrimary (citable) accession number: Q54318
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3