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Q54318 (HLYC_BRAHO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Hemolysin C
Gene names
Name:tlyC
OrganismBrachyspira hyodysenteriae (Treponema hyodysenteriae)
Taxonomic identifier159 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesBrachyspiraceaeBrachyspira

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Hemolysin C
PRO_0000088354

Regions

Domain52 – 11160CBS 1
Domain114 – 17158CBS 2

Sequences

Sequence LengthMass (Da)Tools
Q54318 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: E56A3D43D8764FDA

FASTA26830,764
        10         20         30         40         50         60 
MPIKKLISKI VKKKDSDTEK NNYINLSALT EAEREIITNT IELKSKSVRE IMVPRVDVVM 

        70         80         90        100        110        120 
IPMESSYDKV IKAFNRDRNS RIPVYKDGID DIVGVLYVKD LIDAEEKNFS LKKILHKPLF 

       130        140        150        160        170        180 
VPISISLMEL LKNFREKQIH IAMVVDEYGG FSGIVSMEDV LEQIIGDIRD EYDEEDEEIK 

       190        200        210        220        230        240 
SNDDGTYLVD ARTRIDDFNK YEILPPIPDD EADTVGGFLF SYLGRLPKRN EDIEYNGYSF 

       250        260 
TVVGKSGNIV TKIRIEKLKK DNTAKNKD 

« Hide

References

[1]"Characterization of three putative Serpulina hyodysenteriae hemolysins."
Ter Huurne A.A.H.M., Muir S., van Houten M., van der Zeijst B.A.M., Gaastra W., Kusters J.G.
Microb. Pathog. 16:269-282(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: B204.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X73141 Genomic DNA. Translation: CAA51657.1.
PIRT46749.

3D structure databases

ProteinModelPortalQ54318.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

TCDB9.A.40.1.1. the hlyc/corc (hcc) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHLYC_BRAHO
AccessionPrimary (citable) accession number: Q54318
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families