Q542Y6 (Q542Y6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phospholipase A2, group XIIA, isoform CRA_b EMBL EAX06247.1

Submitted name:
cDNA PSEC0079 fis, clone NT2RP2004049, highly similar to Group XII secretory phospholipase A2 (EC 3.1.1.4) EMBL BAC11589.1
Submitted name:
cDNA, FLJ93563, Homo sapiens phospholipase A2, group XII (PLA2G12), mRNA EMBL BAG35907.1

Gene names

Name:	PLA2G12A EMBL EAX06247.1
ORF Names:	hCG_21046 EMBL EAX06247.1

Organism

Homo sapiens (Human) EMBL BAC11589.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	lipid catabolic process Inferred from electronic annotation. Source: InterPro phospholipid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro phospholipase A2 activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q542Y6 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 7979881D6E9223A4	FASTA	189	21,067
	10 20 30 40 50 60 MALLSRPALT LLLLLMAAVV RCQEQAQTTD WRATLKTIRN GVHKIDTYLN AALDLLGGED 70 80 90 100 110 120 GLCQYKCSDG SKPFPRYGYK PSPPNGCGSP LFGVHLNIGI PSLTKCCNQH DRCYETCGKS 130 140 150 160 170 180 KNDCDEEFQY CLSKICRDVQ KTLGLTQHVQ ACETTVELLF DSVIHLGCKP YLDSQRAACR CHYEEKTDL

References

[1]	"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y. , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T. DNA Res. 12:117-126(2005) [PubMed: 16303743] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Hippocampus EMBL BAG35907.1.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK075389 mRNA. Translation: BAC11589.1. AK313081 mRNA. Translation: BAG35907.1. CH471057 Genomic DNA. Translation: EAX06247.1.
IPI	IPI00017095.
RefSeq	NP_110448.2. NM_030821.4.
UniGene	Hs.389452.
3D structure databases
ProteinModelPortal	Q542Y6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q542Y6.
Proteomic databases
PRIDE	Q542Y6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	81579.
KEGG	hsa:81579.
UCSC	uc010img.1. human.
Organism-specific databases
CTD	81579.
PharmGKB	PA38347.
Phylogenomic databases
eggNOG	prNOG04621.
HOVERGEN	HBG053577.
OMA	TQHVQAC.
PhylomeDB	Q542Y6.
Gene expression databases
ArrayExpress	Q542Y6.
Bgee	Q542Y6.
Family and domain databases
InterPro	IPR016090. PLipase_A2. IPR013090. PLipase_A2_AS. IPR010711. PLipase_A2_secretory_G12. [Graphical view]
Gene3D	G3DSA:1.20.90.10. Phospholipase_A2. 1 hit.
KO	K01047.
PANTHER	PTHR12824. PLA2G12. 1 hit.
Pfam	PF06951. PLA2G12. 1 hit. [Graphical view]
SUPFAM	SSF48619. PhospholipaseA2. 1 hit.
PROSITE	PS00118. PA2_HIS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	71900.

Entry information

Entry name

Q542Y6_HUMAN

Accession

Primary (citable) accession number: Q542Y6

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	November 16, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.