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Q542M5

- Q542M5_MOUSE

UniProt

Q542M5 - Q542M5_MOUSE

Protein

Galectin

Gene

Lgals8

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: MGI

    GO - Biological processi

    1. plasma cell differentiation Source: MGI
    2. T cell costimulation Source: MGI

    Keywords - Ligandi

    LectinUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GalectinUniRule annotation
    Gene namesi
    Name:Lgals8Imported
    ORF Names:mCG_9125Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1928481. Lgals8.

    Expressioni

    Gene expression databases

    GenevestigatoriQ542M5.

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 galectin domains.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000290194.
    HOVERGENiHBG002412.
    KOiK06832.

    Family and domain databases

    Gene3Di2.60.120.200. 2 hits.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001079. Galectin_CRD.
    [Graphical view]
    PfamiPF00337. Gal-bind_lectin. 2 hits.
    [Graphical view]
    SMARTiSM00908. Gal-bind_lectin. 2 hits.
    SM00276. GLECT. 2 hits.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 2 hits.
    PROSITEiPS51304. GALECTIN. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q542M5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSLNNLQNI IYNPIIPYVG TITEQLKPGS LIVIRGHVPK DSERFQVDFQ    50
    LGNSLKPRAD VAFHFNPRFK RSSCIVCNTL TQEKWGWEEI TYDMPFRKEK 100
    SFEIVFMVLK NKFQVAVNGR HVLLYAHRIS PEQIDTVGIY GKVNIHSIGF 150
    RFSSDLQSME TSALGLTQIN RENIQKPGKL QLSLPFEARL NASMGPGRTV 200
    VIKGEVNTNA RSFNVDLVAG KTRDIALHLN PRLNVKAFVR NSFLQDAWGE 250
    EERNITCFPF SSGMYFEMII YCDVREFKVA INGVHSLEYK HRFKDLSSID 300
    TLSVDGDIRL LDVRSW 316
    Length:316
    Mass (Da):36,162
    Last modified:May 24, 2005 - v1
    Checksum:i11A20309AEF52C69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004782 mRNA. Translation: BAB23560.1.
    AK083350 mRNA. Translation: BAC38880.1.
    AK145881 mRNA. Translation: BAE26721.1.
    AK146746 mRNA. Translation: BAE27406.1.
    CT010251 mRNA. Translation: CAJ18459.1.
    CH466588 Genomic DNA. Translation: EDL32308.1.
    CH466588 Genomic DNA. Translation: EDL32309.1.
    CH466588 Genomic DNA. Translation: EDL32310.1.
    CH466588 Genomic DNA. Translation: EDL32312.1.
    RefSeqiNP_001185972.1. NM_001199043.1.
    NP_001277984.1. NM_001291055.1.
    NP_001277986.1. NM_001291057.1.
    NP_001277989.1. NM_001291060.1.
    NP_061374.1. NM_018886.5.
    XP_006516777.1. XM_006516714.1.
    XP_006516778.1. XM_006516715.1.
    UniGeneiMm.474138.
    Mm.486765.

    Genome annotation databases

    GeneIDi56048.
    KEGGimmu:56048.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004782 mRNA. Translation: BAB23560.1 .
    AK083350 mRNA. Translation: BAC38880.1 .
    AK145881 mRNA. Translation: BAE26721.1 .
    AK146746 mRNA. Translation: BAE27406.1 .
    CT010251 mRNA. Translation: CAJ18459.1 .
    CH466588 Genomic DNA. Translation: EDL32308.1 .
    CH466588 Genomic DNA. Translation: EDL32309.1 .
    CH466588 Genomic DNA. Translation: EDL32310.1 .
    CH466588 Genomic DNA. Translation: EDL32312.1 .
    RefSeqi NP_001185972.1. NM_001199043.1.
    NP_001277984.1. NM_001291055.1.
    NP_001277986.1. NM_001291057.1.
    NP_001277989.1. NM_001291060.1.
    NP_061374.1. NM_018886.5.
    XP_006516777.1. XM_006516714.1.
    XP_006516778.1. XM_006516715.1.
    UniGenei Mm.474138.
    Mm.486765.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 56048.
    KEGGi mmu:56048.

    Organism-specific databases

    CTDi 3964.
    MGIi MGI:1928481. Lgals8.

    Phylogenomic databases

    HOGENOMi HOG000290194.
    HOVERGENi HBG002412.
    KOi K06832.

    Miscellaneous databases

    ChiTaRSi LGALS8. mouse.
    NextBioi 311828.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q542M5.

    Family and domain databases

    Gene3Di 2.60.120.200. 2 hits.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR001079. Galectin_CRD.
    [Graphical view ]
    Pfami PF00337. Gal-bind_lectin. 2 hits.
    [Graphical view ]
    SMARTi SM00908. Gal-bind_lectin. 2 hits.
    SM00276. GLECT. 2 hits.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 2 hits.
    PROSITEi PS51304. GALECTIN. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ThymusImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported and PlacentaImported.
    10. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    11. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: KidneyImported, LungImported, PlacentaImported and ThymusImported.
    12. "Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
      Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    13. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.

    Entry informationi

    Entry nameiQ542M5_MOUSE
    AccessioniPrimary (citable) accession number: Q542M5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)