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Protein

Annexin

Gene

Anxa2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:Anxa2Imported
ORF Names:mCG_5731Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88246. Anxa2.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

MaxQBiQ542G9.
TopDownProteomicsiQ542G9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000032231.
ExpressionAtlasiQ542G9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034756.

Structurei

3D structure databases

SMRiQ542G9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
HOVERGENiHBG061815.
KOiK17092.
OMAiFIQQDTK.
OrthoDBiEOG091G0H6H.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiView protein in InterPro
IPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR002389. ANX2.
PANTHERiPTHR10502:SF151. PTHR10502:SF151. 1 hit.
PfamiView protein in Pfam
PF00191. Annexin. 4 hits.
PRINTSiPR00196. ANNEXIN.
PR00198. ANNEXINII.
SMARTiView protein in SMART
SM00335. ANX. 4 hits.
PROSITEiView protein in PROSITE
PS00223. ANNEXIN. 4 hits.

Sequencei

Sequence statusi: Complete.

Q542G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTVHEILCK LSLEGDHSTP PSAYGSVKPY TNFDAERDAL NIETAVKTKG
60 70 80 90 100
VDEVTIVNIL TNRSNVQRQD IAFAYQRRTK KELPSALKSA LSGHLETVIL
110 120 130 140 150
GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM
160 170 180 190 200
YKTDLEKDII SDTSGDFRKL MVALAKGRRA EDGSVIDYEL IDQDARELYD
210 220 230 240 250
AGVKRKGTDV PKWISIMTER SVCHLQKVFE RYKSYSPYDM LESIKKEVKG
260 270 280 290 300
DLENAFLNLV QCIQNKPLYF ADRLYDSMKG KGTRDKVLIR IMVSRSEVDM
310 320 330
LKIRSEFKRK YGKSLYYYIQ QDTKGDYQKA LLYLCGGDD
Length:339
Mass (Da):38,676
Last modified:May 24, 2005 - v1
Checksum:i4407E572097FB2C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK088645 mRNA. Translation: BAC40474.1.
AK146096 mRNA. Translation: BAE26899.1.
AK152561 mRNA. Translation: BAE31314.1.
AK164507 mRNA. Translation: BAE37816.1.
AK165888 mRNA. Translation: BAE38439.1.
AK167894 mRNA. Translation: BAE39905.1.
AK168083 mRNA. Translation: BAE40056.1.
CH466522 Genomic DNA. Translation: EDL26171.1.
CH466522 Genomic DNA. Translation: EDL26172.1.
CH466522 Genomic DNA. Translation: EDL26173.1.
RefSeqiNP_031611.1. NM_007585.3.
XP_006510859.1. XM_006510796.2.
UniGeneiMm.238343.

Genome annotation databases

GeneIDi12306.
KEGGimmu:12306.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK088645 mRNA. Translation: BAC40474.1.
AK146096 mRNA. Translation: BAE26899.1.
AK152561 mRNA. Translation: BAE31314.1.
AK164507 mRNA. Translation: BAE37816.1.
AK165888 mRNA. Translation: BAE38439.1.
AK167894 mRNA. Translation: BAE39905.1.
AK168083 mRNA. Translation: BAE40056.1.
CH466522 Genomic DNA. Translation: EDL26171.1.
CH466522 Genomic DNA. Translation: EDL26172.1.
CH466522 Genomic DNA. Translation: EDL26173.1.
RefSeqiNP_031611.1. NM_007585.3.
XP_006510859.1. XM_006510796.2.
UniGeneiMm.238343.

3D structure databases

SMRiQ542G9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034756.

Proteomic databases

MaxQBiQ542G9.
TopDownProteomicsiQ542G9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12306.
KEGGimmu:12306.

Organism-specific databases

CTDi302.
MGIiMGI:88246. Anxa2.

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
HOVERGENiHBG061815.
KOiK17092.
OMAiFIQQDTK.
OrthoDBiEOG091G0H6H.

Miscellaneous databases

ChiTaRSiAnxa2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000032231.
ExpressionAtlasiQ542G9. baseline and differential.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiView protein in InterPro
IPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR002389. ANX2.
PANTHERiPTHR10502:SF151. PTHR10502:SF151. 1 hit.
PfamiView protein in Pfam
PF00191. Annexin. 4 hits.
PRINTSiPR00196. ANNEXIN.
PR00198. ANNEXINII.
SMARTiView protein in SMART
SM00335. ANX. 4 hits.
PROSITEiView protein in PROSITE
PS00223. ANNEXIN. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ542G9_MOUSE
AccessioniPrimary (citable) accession number: Q542G9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 15, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.