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Protein
Submitted name:

Cysteine/glutamate transporter

Gene

Slc7a11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine/glutamate transporterImported
Submitted name:
Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 11Imported
Gene namesi
Name:Slc7a11Imported
ORF Names:mCG_20789Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1347355. Slc7a11.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 64HelicalSequence analysisAdd BLAST20
Transmembranei76 – 98HelicalSequence analysisAdd BLAST23
Transmembranei163 – 180HelicalSequence analysisAdd BLAST18
Transmembranei192 – 214HelicalSequence analysisAdd BLAST23
Transmembranei234 – 254HelicalSequence analysisAdd BLAST21
Transmembranei266 – 289HelicalSequence analysisAdd BLAST24
Transmembranei317 – 343HelicalSequence analysisAdd BLAST27
Transmembranei364 – 382HelicalSequence analysisAdd BLAST19
Transmembranei394 – 412HelicalSequence analysisAdd BLAST19
Transmembranei424 – 444HelicalSequence analysisAdd BLAST21
Transmembranei450 – 470HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000027737.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1287. Eukaryota.
COG0531. LUCA.
HOVERGENiHBG000476.
KOiK13869.
OMAiTGIPAYY.
OrthoDBiEOG091G07EM.

Family and domain databases

InterProiView protein in InterPro
IPR002293. AA/rel_permease1.
IPR004760. L_AA_transporter.
PfamiView protein in Pfam
PF13520. AA_permease_2. 1 hit.
PIRSFiPIRSF006060. AA_transporter. 1 hit.
TIGRFAMsiTIGR00911. 2A0308. 1 hit.

Sequencei

Sequence statusi: Complete.

Q542C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRKPVVATI SKGGYLQGNM SGRLPSMGDQ EPPGQEKVVL KKKITLLRGV
60 70 80 90 100
SIIIGTVIGS GIFISPKGIL QNTGSVGMSL VFWSACGVLS LFGALSYAEL
110 120 130 140 150
GTSIKKSGGH YTYILEVFGP LLAFVRVWVE LLVIRPGATA VISLAFGRYI
160 170 180 190 200
LEPFFIQCEI PELAIKLVTA VGITVVMVLN STSVSWSARI QIFLTFCKLT
210 220 230 240 250
AILIIIVPGV IQLIKGQTHH FKDAFSGRDT SLMGLPLAFY YGMYAYAGWF
260 270 280 290 300
YLNFITEEVD NPEKTIPLAI CISMAIITVG YVLTNVAYFT TISAEELLQS
310 320 330 340 350
SAVAVTFSER LLGKFSLAVP IFVALSCFGS MNGGVFAVSR LFYVASREGH
360 370 380 390 400
LPEILSMIHV HKHTPLPAVI VLHPLTMVML FSGDLYSLLN FLSFARWLFM
410 420 430 440 450
GLAVAGLIYL RYKRPDMHRP FKVPLFIPAL FSFTCLFMVV LSLYSDPFST
460 470 480 490 500
GVGFLITLTG VPAYYLFIVW DKKPKWFRRL SDRITRTLQI ILEVVPEDSK

EL
Length:502
Mass (Da):55,456
Last modified:May 24, 2005 - v1
Checksum:iA4A185102D83992A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC141402 mRNA. Translation: AAI41403.1.
BC141408 mRNA. Translation: AAI41409.1.
AY766236 mRNA. Translation: AAX10866.1.
AK089202 mRNA. Translation: BAC40792.1.
AK163168 mRNA. Translation: BAE37218.1.
AK171192 mRNA. Translation: BAE42302.1.
AK171252 mRNA. Translation: BAE42344.1.
CH466530 Genomic DNA. Translation: EDL35191.1.
RefSeqiNP_036120.1. NM_011990.2.
UniGeneiMm.260988.

Genome annotation databases

GeneIDi26570.
KEGGimmu:26570.

Similar proteinsi

Entry informationi

Entry nameiQ542C8_MOUSE
AccessioniPrimary (citable) accession number: Q542C8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)