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Protein
Submitted name:

Ketoreductase/dehydrogenase

Gene

rapT

Organism
Streptomyces hygroscopicus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ketoreductase/dehydrogenaseImported
Gene namesi
Name:rapTImported
OrganismiStreptomyces hygroscopicusImported
Taxonomic identifieri1912 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Structurei

3D structure databases

ProteinModelPortaliQ54295.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 3 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54295-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTLEHRFA GQVALVTGGG SGIGAAVAHL LAAEGCAAVH VGDLNAEGVR
60 70 80 90 100
TVASVIKGVA HVVDVTDPRA VDAVVSSVLE SEGRIDVVIH TAGVDDPDAK
110 120 130 140 150
ARILEAQESG EPVDVLTRLD DAAWRRVMAV NLDGTFHVLR AAVRAMRPRG
160 170 180 190 200
RGAIVTVGSS AAFDTLTGYP HYAASKAGVH ALSQAVAKEA IAFGIRVNTV
210 220 230 240 250
APGPVDTPMA ARTPDAVRQK MAESGASGYA TPEELADNIC YLASPAASNV
260
VGAVLLSNGG RFTV
Length:264
Mass (Da):26,934
Last modified:November 1, 1996 - v1
Checksum:iF6987C7F0EC9778A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86780 Genomic DNA. Translation: CAA60458.1.
PIRiT30224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86780 Genomic DNA. Translation: CAA60458.1.
PIRiT30224.

3D structure databases

ProteinModelPortaliQ54295.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 3 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NRRL 5491Imported.
  2. "Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase."
    Molnar I., Aparicio J.F., Haydock S.F., Khaw L.E., Schwecke T., Konig A., Staunton J., Leadlay P.F.
    Gene 169:1-7(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NRRL 5491Imported.
  3. "Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase."
    Aparicio J.F., Molnar I., Schwecke T., Koenig A., Haydock S.F., Khaw L.E., Staunton J., Leadlay P.F., Staunton J., Leadlay P.F.
    Gene 169:9-16(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NRRL 5491Imported.

Entry informationi

Entry nameiQ54295_STRHY
AccessioniPrimary (citable) accession number: Q54295
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 13, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.