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Protein
Submitted name:

Septin 6

Gene

SEPT6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Septin 6Imported
Submitted name:
Septin 6, isoform CRA_dImported
Submitted name:
cDNA FLJ58747, highly similar to Septin-6Imported
Gene namesi
Name:SEPT6Imported
ORF Names:hCG_23191Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000125354.22.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134941944.

PTM / Processingi

Proteomic databases

MaxQBiQ541S4.

Expressioni

Gene expression databases

BgeeiENSG00000125354.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305Septin-type GInterPro annotationAdd BLAST267

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili343 – 399Sequence analysisAdd BLAST57

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2655. Eukaryota.
COG5019. LUCA.
HOVERGENiHBG065093.

Family and domain databases

CDDicd01850. CDC_Septin. 1 hit.
InterProiView protein in InterPro
IPR030379. G_SEPTIN_dom.
IPR027417. P-loop_NTPase.
IPR030644. SEPT6.
IPR016491. Septin.
PANTHERiPTHR18884:SF55. PTHR18884:SF55. 1 hit.
PfamiView protein in Pfam
PF00735. Septin. 1 hit.
PIRSFiPIRSF006698. Septin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS51719. G_SEPTIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q541S4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE
60 70 80 90 100
TGLGKSTLMD TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV
110 120 130 140 150
STVGFGDQIN KEDSYKPIVE FIDAQFEAYL QEELKIRRVL HTYHDSRIHV
160 170 180 190 200
CLYFIAPTGH SLKSLDLVTM KKLDSKVNII PIIAKADAIS KSELTKFKIK
210 220 230 240 250
ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS TEELKIGNKM
260 270 280 290 300
MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV
360 370 380 390 400
KEKEAELKEA EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK
410 420
TAAELLQSQG SQAGGSQTLK RDKEKKN
Length:427
Mass (Da):48,873
Last modified:February 5, 2008 - v1
Checksum:i62EB88E308386ADE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY005981 mRNA. Translation: AAF97496.1.
AY034177 mRNA. Translation: AAK61492.1.
AK299273 mRNA. Translation: BAG61293.1.
CH471161 Genomic DNA. Translation: EAW89854.1.
CH471161 Genomic DNA. Translation: EAW89856.1.
RefSeqiNP_665798.1. NM_145799.3.
NP_665799.1. NM_145800.3.
XP_006724813.1. XM_006724750.2.
UniGeneiHs.496666.

Genome annotation databases

GeneIDi23157.
UCSCiuc004ers.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ541S4_HUMAN
AccessioniPrimary (citable) accession number: Q541S4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 22, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.