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Protein
Submitted name:

Interferon alpha 4

Gene

Ifna4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon alpha 4Imported
Submitted name:
MCG123696Imported
Gene namesi
Name:Ifna4Imported
ORF Names:mCG_123696Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107664. Ifna4.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501013925421 – 186Sequence analysisAdd BLAST166

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000070904.
ExpressionAtlasiQ540C2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ540C2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J735. Eukaryota.
ENOG410ZH91. LUCA.
HOVERGENiHBG052086.
KOiK05414.
OMAiISAFHEM.
OrthoDBiEOG091G0MOL.

Family and domain databases

CDDicd00095. IFab. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR000471. Interferon_alpha/beta/delta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.

Sequencei

Sequence statusi: Complete.

Q540C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLCAFLMI LVMMSYYWSA CSLGCDLPHT YNLGNKRALT VLEEMRRLPP
60 70 80 90 100
LSCLKDRKDF GFPLEKVDNQ QIQKAQAILV LRDLTQQILN LFTSKDLSAT
110 120 130 140 150
WNATLLDSFC NDLHQQLNDL KACVMQEPPL TQEDSLLAVR TYFHRITVYL
160 170 180
RKKKHSLCAW EVIRAEVWRA LSSSTNLLAR LSEEKE
Length:186
Mass (Da):21,524
Last modified:May 24, 2005 - v1
Checksum:iFC5D46D473741794
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116217 mRNA. Translation: AAI16218.1.
BC119349 mRNA. Translation: AAI19350.1.
BC119351 mRNA. Translation: AAI19352.1.
AY220463 Genomic DNA. Translation: AAO64456.1.
CH466527 Genomic DNA. Translation: EDL30959.1.
RefSeqiNP_034634.1. NM_010504.2.
UniGeneiMm.377088.

Genome annotation databases

GeneIDi15967.
KEGGimmu:15967.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ540C2_MOUSE
AccessioniPrimary (citable) accession number: Q540C2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)