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Protein
Submitted name:

HCG1 protein

Gene

ZNF165

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
HCG1 proteinImported
Submitted name:
Zinc finger protein 165Imported
Gene namesi
Name:ZNF165Imported
ORF Names:hCG_31427Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37535.

PTM / Processingi

Proteomic databases

MaxQBiQ53Z40.

Expressioni

Gene expression databases

BgeeiENSG00000197279.
ExpressionAtlasiQ53Z40. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ53Z40. 8 interactors.
STRINGi9606.ENSP00000366542.

Structurei

3D structure databases

SMRiQ53Z40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 129SCAN boxInterPro annotationAdd BLAST81
Domaini290 – 319C2H2-typeInterPro annotationAdd BLAST30
Domaini344 – 371C2H2-typeInterPro annotationAdd BLAST28
Domaini372 – 399C2H2-typeInterPro annotationAdd BLAST28
Domaini400 – 427C2H2-typeInterPro annotationAdd BLAST28
Domaini428 – 455C2H2-typeInterPro annotationAdd BLAST28
Domaini456 – 483C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG018163.
KOiK09230.
OMAiVKRQWEK.
OrthoDBiEOG091G09O3.
PhylomeDBiQ53Z40.

Family and domain databases

Gene3Di3.30.160.60. 6 hits.
InterProiView protein in InterPro
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequencei

Sequence statusi: Complete.

Q53Z40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEPKKAAA QNSPEDEGLL IVKIEEEEFI HGQDTCLQRS ELLKQELCRQ
60 70 80 90 100
LFRQFCYQDS PGPREALSRL RELCCQWLKP EIHTKEQILE LLVLEQFLTI
110 120 130 140 150
LPGDLQAWVH EHYPESGEEA VTILEDLERG TDEAVLQVQA HEHGQEIFQK
160 170 180 190 200
KVSPPGPALN VKLQPVETKA HFDSSEPQLL WDCDNESENS RSMPKLEIFE
210 220 230 240 250
KIESQRIISG RISGYISEAS GESQDICKSA GRVKRQWEKE SGESQRLSSA
260 270 280 290 300
QDEGFGKILT HKNTVRGEII SHDGCERRLN LNSNEFTHQK SCKHGTCDQS
310 320 330 340 350
FKWNSDFINH QIIYAGEKNH QYGKSFKSPK LAKHAAVFSG DKTHQCNECG
360 370 380 390 400
KAFRHSSKLA RHQRIHTGER CYECNECGKS FAESSDLTRH RRIHTGERPF
410 420 430 440 450
GCKECGRAFN LNSHLIRHQR IHTREKPYEC SECGKTFRVS SHLIRHFRIH
460 470 480
TGEKPYECSE CGRAFSQSSN LSQHQRIHMR ENLLM
Length:485
Mass (Da):55,771
Last modified:May 24, 2005 - v1
Checksum:i1265D859D1713AE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY083664 mRNA. Translation: AAM08933.1.
AY366500 mRNA. Translation: AAQ73196.1.
CH471081 Genomic DNA. Translation: EAX03131.1.
RefSeqiNP_003438.1. NM_003447.3.
XP_016866747.1. XM_017011258.1.
XP_016866748.1. XM_017011259.1.
XP_016866749.1. XM_017011260.1.
UniGeneiHs.55481.

Genome annotation databases

GeneIDi7718.
KEGGihsa:7718.
UCSCiuc021yro.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY083664 mRNA. Translation: AAM08933.1.
AY366500 mRNA. Translation: AAQ73196.1.
CH471081 Genomic DNA. Translation: EAX03131.1.
RefSeqiNP_003438.1. NM_003447.3.
XP_016866747.1. XM_017011258.1.
XP_016866748.1. XM_017011259.1.
XP_016866749.1. XM_017011260.1.
UniGeneiHs.55481.

3D structure databases

SMRiQ53Z40.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ53Z40. 8 interactors.
STRINGi9606.ENSP00000366542.

Proteomic databases

MaxQBiQ53Z40.

Protocols and materials databases

DNASUi7718.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7718.
KEGGihsa:7718.
UCSCiuc021yro.2. human.

Organism-specific databases

CTDi7718.
PharmGKBiPA37535.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOVERGENiHBG018163.
KOiK09230.
OMAiVKRQWEK.
OrthoDBiEOG091G09O3.
PhylomeDBiQ53Z40.

Miscellaneous databases

GenomeRNAii7718.

Gene expression databases

BgeeiENSG00000197279.
ExpressionAtlasiQ53Z40. baseline and differential.

Family and domain databases

Gene3Di3.30.160.60. 6 hits.
InterProiView protein in InterPro
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 4 hits.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ53Z40_HUMAN
AccessioniPrimary (citable) accession number: Q53Z40
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: February 15, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.