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Protein
Submitted name:

Inward rectifying potassium channel Kir4.2

Gene

Kcnj15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei157Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesiumUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Voltage-gated channelUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Inward rectifying potassium channel Kir4.2Imported
Submitted name:
Kcnj15 proteinImported
Submitted name:
Potassium inwardly rectifying channelImported
Submitted name:
Potassium inwardly-rectifying channel, subfamily J, member 15, isoform CRA_aImported
Gene namesi
Name:Kcnj15Imported
Synonyms:Kir4.2Imported
ORF Names:mCG_2220Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1310000. Kcnj15.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei67 – 88HelicalSequence analysisAdd BLAST22
Transmembranei142 – 166HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000062609.

Structurei

3D structure databases

SMRiQ53Z04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
HOVERGENiHBG006178.
KOiK05008.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiView protein in InterPro
IPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003270. K_chnl_inward-rec_Kir1.3.
IPR013518. K_chnl_inward-rec_Kir_cyto.
PANTHERiPTHR11767. PTHR11767. 1 hit.
PTHR11767:SF90. PTHR11767:SF90. 1 hit.
PfamiView protein in Pfam
PF01007. IRK. 1 hit.
PIRSFiPIRSF005465. GIRK_kir. 1 hit.
PRINTSiPR01323. KIR13CHANNEL.
PR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53Z04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIHLGMSS APLVKHTNGV GLKAHRPRVM SKSGHSNVRI DKVDGIYLLY
60 70 80 90 100
LQDLWTTVID MKWRYKLTLF AATFVMTWFL FGVVYYAIAF IHGDLQLGES
110 120 130 140 150
NSNHTPCIMK VDSLTGAFLF SLESQTTIGY GVRSITEECP HAIFLLVAQL
160 170 180 190 200
VITTLIEIFI TGTFLAKIAR PKKRAETIKF SHCAVISKQN GKLCLVIQVA
210 220 230 240 250
NMRKSLLIQC QLSGKLLQTH VTKEGERILL NQATVKFHVD SSSESPFLIL
260 270 280 290 300
PMTFYHVLDE TSPLRDLTPQ NLKEKEFELV VLLNATVEST SAVCQSRTSY
310 320 330 340 350
IPEEIYWGFE FVPVVSLSKN GKYVADFSQF EQIRKSPDCT FYCADSEKQK
360 370
LEEQYRQEDQ RERELRSLLL QQSNV
Length:375
Mass (Da):42,605
Last modified:May 24, 2005 - v1
Checksum:i163277597D4B2C8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138478 mRNA. Translation: AAI38479.1.
AY377988 mRNA. Translation: AAQ88166.1.
AK165436 mRNA. Translation: BAE38186.1.
AJ300831 mRNA. Translation: CAC83656.1.
CH466602 Genomic DNA. Translation: EDL03715.1.
CH466602 Genomic DNA. Translation: EDL03716.1.
RefSeqiNP_001034145.1. NM_001039056.2.
NP_001034146.1. NM_001039057.2.
NP_001258616.1. NM_001271687.1.
NP_001258618.1. NM_001271689.1.
NP_001258619.1. NM_001271690.1.
NP_001258620.1. NM_001271691.1.
NP_001258622.1. NM_001271693.1.
NP_001258623.1. NM_001271694.1.
NP_001258624.1. NM_001271695.1.
NP_062638.1. NM_019664.5.
XP_006523014.1. XM_006522951.3.
XP_006523015.1. XM_006522952.3.
XP_017172374.1. XM_017316885.1.
UniGeneiMm.272239.
Mm.491313.

Genome annotation databases

GeneIDi16516.
KEGGimmu:16516.

Similar proteinsi

Entry informationi

Entry nameiQ53Z04_MOUSE
AccessioniPrimary (citable) accession number: Q53Z04
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)