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Protein
Submitted name:

Inward rectifying potassium channel Kir4.2

Gene

Kcnj15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei157Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Voltage-gated channelUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Inward rectifying potassium channel Kir4.2Imported
Submitted name:
Kcnj15 proteinImported
Submitted name:
Potassium inwardly rectifying channelImported
Submitted name:
Potassium inwardly-rectifying channel, subfamily J, member 15, isoform CRA_aImported
Gene namesi
Name:Kcnj15Imported
Synonyms:Kir4.2Imported
ORF Names:mCG_2220Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1310000 Kcnj15

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei67 – 88HelicalSequence analysisAdd BLAST22
Transmembranei142 – 166HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000062609

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili348 – 368Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827 Eukaryota
ENOG410XQ62 LUCA
HOVERGENiHBG006178
KOiK05008

Family and domain databases

Gene3Di2.60.40.1400, 2 hits
InterProiView protein in InterPro
IPR014756 Ig_E-set
IPR016449 K_chnl_inward-rec_Kir
IPR003270 K_chnl_inward-rec_Kir1.3
IPR013518 K_chnl_inward-rec_Kir_cyto
PANTHERiPTHR11767 PTHR11767, 1 hit
PTHR11767:SF20 PTHR11767:SF20, 1 hit
PfamiView protein in Pfam
PF01007 IRK, 1 hit
PIRSFiPIRSF005465 GIRK_kir, 1 hit
PRINTSiPR01323 KIR13CHANNEL
PR01320 KIRCHANNEL
SUPFAMiSSF81296 SSF81296, 1 hit

Sequencei

Sequence statusi: Complete.

Q53Z04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIHLGMSS APLVKHTNGV GLKAHRPRVM SKSGHSNVRI DKVDGIYLLY
60 70 80 90 100
LQDLWTTVID MKWRYKLTLF AATFVMTWFL FGVVYYAIAF IHGDLQLGES
110 120 130 140 150
NSNHTPCIMK VDSLTGAFLF SLESQTTIGY GVRSITEECP HAIFLLVAQL
160 170 180 190 200
VITTLIEIFI TGTFLAKIAR PKKRAETIKF SHCAVISKQN GKLCLVIQVA
210 220 230 240 250
NMRKSLLIQC QLSGKLLQTH VTKEGERILL NQATVKFHVD SSSESPFLIL
260 270 280 290 300
PMTFYHVLDE TSPLRDLTPQ NLKEKEFELV VLLNATVEST SAVCQSRTSY
310 320 330 340 350
IPEEIYWGFE FVPVVSLSKN GKYVADFSQF EQIRKSPDCT FYCADSEKQK
360 370
LEEQYRQEDQ RERELRSLLL QQSNV
Length:375
Mass (Da):42,605
Last modified:May 24, 2005 - v1
Checksum:i163277597D4B2C8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC138478 mRNA Translation: AAI38479.1
AY377988 mRNA Translation: AAQ88166.1
AK165436 mRNA Translation: BAE38186.1
AJ300831 mRNA Translation: CAC83656.1
CH466602 Genomic DNA Translation: EDL03715.1
CH466602 Genomic DNA Translation: EDL03716.1
RefSeqiNP_001034145.1, NM_001039056.2
NP_001034146.1, NM_001039057.2
NP_001258616.1, NM_001271687.1
NP_001258618.1, NM_001271689.1
NP_001258619.1, NM_001271690.1
NP_001258620.1, NM_001271691.1
NP_001258622.1, NM_001271693.1
NP_001258623.1, NM_001271694.1
NP_001258624.1, NM_001271695.1
NP_062638.1, NM_019664.5
XP_006523014.1, XM_006522951.3
XP_006523015.1, XM_006522952.3
XP_017172374.1, XM_017316885.1
UniGeneiMm.272239
Mm.491313

Genome annotation databases

GeneIDi16516
KEGGimmu:16516

Similar proteinsi

Entry informationi

Entry nameiQ53Z04_MOUSE
AccessioniPrimary (citable) accession number: Q53Z04
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health