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Q53YY3

- Q53YY3_MOUSE

UniProt

Q53YY3 - Q53YY3_MOUSE

Protein
Submitted name:

Adiponectin receptor 2, isoform CRA_a

Gene

Adipor2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adiponectin binding Source: MGI
    2. hormone binding Source: RefGenome
    3. identical protein binding Source: MGI
    4. protein heterodimerization activity Source: MGI
    5. receptor activity Source: MGI

    GO - Biological processi

    1. adiponectin-activated signaling pathway Source: MGI
    2. female pregnancy Source: Ensembl
    3. heart development Source: Ensembl
    4. negative regulation of cell growth Source: Ensembl
    5. positive regulation of glucose import Source: Ensembl
    6. response to nutrient Source: Ensembl

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adiponectin receptor 2, isoform CRA_aImported
    Submitted name:
    Progestin and adipoQ receptor family member IIImported
    Gene namesi
    Name:Adipor2Imported
    Synonyms:Paqr2Imported
    ORF Names:mCG_131717Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:93830. Adipor2.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro
    2. plasma membrane Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ53YY3.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG013916.
    InParanoidiQ53YY3.
    KOiK07297.
    OMAiYMFRPNM.

    Family and domain databases

    InterProiIPR004254. HlyIII-related.
    [Graphical view]
    PANTHERiPTHR20855. PTHR20855. 1 hit.
    PfamiPF03006. HlyIII. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q53YY3-1 [UniParc]FASTAAdd to Basket

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    MNEPAKHRLG CTRTPEPDIR LRKGHQLDDT RGSNNDNYQG DLEPSLETPV    50
    CSSYYENSPE EPECHDDNSQ EDEGFMGMSP LLQAHHAMER MEEFVCKVWE 100
    GRWRVIPHDV LPDWLKDNDF LLHGHRPPMP SFRACFKSIF RIHTETGNIW 150
    THLLGCVFFL CLGIFYMFRP NISFVAPLQE KVVFGLFFLG AILCLSFSWL 200
    FHTVYCHSEG VSRLFSKLDY SGIALLIMGS FVPWLYYSFY CNPQPCFIYL 250
    IVICVLGIAA IIVSQWDMFA TPQYRGVRAG VFVGLGLSGI IPTLHYVISE 300
    GFLKAATIGQ IGWLMLMASL YITGAALYAA RIPERFFPGK CDIWFHSHQL 350
    FHIFVVAGAF VHFHGVSNLQ EFRFMIGGGC TEEDAL 386
    Length:386
    Mass (Da):43,981
    Last modified:May 24, 2005 - v1
    Checksum:i7760178D3A52E9CA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424291 mRNA. Translation: AAR08379.1.
    AK134787 mRNA. Translation: BAE22285.1.
    AK148295 mRNA. Translation: BAE28463.1.
    AK160534 mRNA. Translation: BAE35851.1.
    CH466523 Genomic DNA. Translation: EDK99609.1.
    RefSeqiNP_932102.2. NM_197985.3.
    XP_006506601.1. XM_006506538.1.
    UniGeneiMm.291826.

    Genome annotation databases

    GeneIDi68465.
    KEGGimmu:68465.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424291 mRNA. Translation: AAR08379.1 .
    AK134787 mRNA. Translation: BAE22285.1 .
    AK148295 mRNA. Translation: BAE28463.1 .
    AK160534 mRNA. Translation: BAE35851.1 .
    CH466523 Genomic DNA. Translation: EDK99609.1 .
    RefSeqi NP_932102.2. NM_197985.3.
    XP_006506601.1. XM_006506538.1.
    UniGenei Mm.291826.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 68465.
    KEGGi mmu:68465.

    Organism-specific databases

    CTDi 79602.
    MGIi MGI:93830. Adipor2.

    Phylogenomic databases

    HOVERGENi HBG013916.
    InParanoidi Q53YY3.
    KOi K07297.
    OMAi YMFRPNM.

    Miscellaneous databases

    ChiTaRSi ADIPOR2. mouse.
    NextBioi 327220.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q53YY3.

    Family and domain databases

    InterProi IPR004254. HlyIII-related.
    [Graphical view ]
    PANTHERi PTHR20855. PTHR20855. 1 hit.
    Pfami PF03006. HlyIII. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    7. "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."
      Tang Y.T., Hu T., Arterburn M., Boyle B., Bright J., Emtage P., Funk W.
      Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
    10. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    11. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Medulla oblongataImported.
    12. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.

    Entry informationi

    Entry nameiQ53YY3_MOUSE
    AccessioniPrimary (citable) accession number: Q53YY3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)