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Protein
Submitted name:

Angiotensin II receptor, type 1, isoform CRA_b

Gene

AGTR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Angiotensin II receptor, type 1, isoform CRA_bImported
Submitted name:
cDNA FLJ75705, highly similar to Homo sapiens angiotensin II receptor, type 1 (AGTR1), transcript variant 1, mRNAImported
Gene namesi
Name:AGTR1Imported
ORF Names:hCG_2022206Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000144891.17

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 56HelicalSequence analysisAdd BLAST23
Transmembranei68 – 90HelicalSequence analysisAdd BLAST23
Transmembranei110 – 131HelicalSequence analysisAdd BLAST22
Transmembranei143 – 165HelicalSequence analysisAdd BLAST23
Transmembranei201 – 218HelicalSequence analysisAdd BLAST18
Transmembranei238 – 262HelicalSequence analysisAdd BLAST25
Transmembranei282 – 305HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA43

Expressioni

Gene expression databases

BgeeiENSG00000144891
ExpressionAtlasiQ53YY0 baseline and differential

Structurei

3D structure databases

SMRiQ53YY0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 302G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST258

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
HOVERGENiHBG104998
KOiK04166

Family and domain databases

CDDicd15192 7tmA_AT1R, 1 hit
InterProiView protein in InterPro
IPR000190 ATII_AT1_rcpt
IPR000248 ATII_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00241 ANGIOTENSINR
PR00635 ANGIOTENSN1R
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q53YY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFGNSLVV
60 70 80 90 100
IVIYFYMKLK TVASVFLLNL ALADLCFLLT LPLWAVYTAM EYRWPFGNYL
110 120 130 140 150
CKIASASVSF NLYASVFLLT CLSIDRYLAI VHPMKSRLRR TMLVAKVTCI
160 170 180 190 200
IIWLLAGLAS LPAIIHRNVF FIENTNITVC AFHYESQNST LPIGLGLTKN
210 220 230 240 250
ILGFLFPFLI ILTSYTLIWK ALKKAYEIQK NKPRNDDIFK IIMAIVLFFF
260 270 280 290 300
FSWIPHQIFT FLDVLIQLGI IRDCRIADIV DTAMPITICI AYFNNCLNPL
310 320 330 340 350
FYGFLGKKFK RYFLQLLKYI PPKAKSHSNL STKMSTLSYR PSDNVSSSTK

KPAPCFEVE
Length:359
Mass (Da):41,061
Last modified:May 24, 2005 - v1
Checksum:i35FC856F53E911A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY436325 Genomic DNA Translation: AAR03503.1
EU332837 Genomic DNA Translation: ABY87526.1
AK291541 mRNA Translation: BAF84230.1
CH471052 Genomic DNA Translation: EAW78906.1
CH471052 Genomic DNA Translation: EAW78907.1
RefSeqiNP_000676.1, NM_000685.4
NP_033611.1, NM_009585.3
UniGeneiHs.477887
Hs.744837

Genome annotation databases

GeneIDi185
KEGGihsa:185
UCSCiuc003ewi.3 human

Similar proteinsi

Entry informationi

Entry nameiQ53YY0_HUMAN
AccessioniPrimary (citable) accession number: Q53YY0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 20, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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