Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cytochrome P450 17-alpha hydroxylase/17,20 lyase

Gene

Cyp17a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseImported, MonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 17-alpha hydroxylase/17,20 lyaseImported
Submitted name:
Cytochrome P450, family 17, subfamily a, polypeptide 1Imported
Gene namesi
Name:Cyp17a1Imported
Synonyms:Cyp17Imported
ORF Names:mCG_21999Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88586. Cyp17a1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501013923719 – 507Sequence analysisAdd BLAST489

Proteomic databases

MaxQBiQ53YJ1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000003555.
ExpressionAtlasiQ53YJ1. baseline and differential.

Structurei

3D structure databases

SMRiQ53YJ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG106944.
KOiK00512.
OMAiYGPIYSF.
OrthoDBiEOG091G0BT8.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53YJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWELVGLLLL ILAYFFWPKS KTPNAKFPRS LPFLPLVGSL PFLPRRGHMH
60 70 80 90 100
ANFFKLQEKY GPIYSLRLGT TTAVIVGHYQ LAREVLVKKG KEFSGRPQMV
110 120 130 140 150
TLGLLSDQGK GVAFADSSSS WQLHRKLVFS TFSLFRDDQK LEKMICQEAN
160 170 180 190 200
SLCDLILTYD GESRDLSTLI FKSVINIICT ICFNISFENK DPILTTIQTF
210 220 230 240 250
TEGIVDVLGH SDLVDIFPWL KIFPNKNLEM IKEHTKIREK TLVEMFEKCK
260 270 280 290 300
EKFNSESLSS LTDILIQAKM NAENNNTGEG QDPSVFSDKH ILVTVGDIFG
310 320 330 340 350
AGIETTSSVL NWILAFLVHN PEVKRKIQKE IDQYVGFSRT PSFNDRTHLL
360 370 380 390 400
MLEATIREVL RIRPVAPLLI PHKANIDSSI GEFAIPKDTH VIINLWALHH
410 420 430 440 450
DKNEWDQPDR FMPERFLDPT GSHLITPTPS YLPFGAGPRS CIGEALARQE
460 470 480 490 500
LFIFMALLLQ RFDFDVSDDK QLPCLVGDPK VVFLIDPFKV KITVRQAWKD

AQVEVST
Length:507
Mass (Da):57,638
Last modified:May 24, 2005 - v1
Checksum:iC0916193356EFEBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY594330 Genomic DNA. Translation: AAT01928.1.
CH466534 Genomic DNA. Translation: EDL42014.1.
RefSeqiNP_031835.3. NM_007809.3.
UniGeneiMm.1262.

Genome annotation databases

GeneIDi13074.
KEGGimmu:13074.

Similar proteinsi

Entry informationi

Entry nameiQ53YJ1_MOUSE
AccessioniPrimary (citable) accession number: Q53YJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)