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Protein
Submitted name:

EEF1G protein

Gene

EEF1G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorPROSITE-ProRule annotationImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
EEF1G proteinImported
Submitted name:
Eukaryotic translation elongation factor 1 gammaImported
Submitted name:
Eukaryotic translation elongation factor 1 gamma, isoform CRA_cImported
Submitted name:
GIG35Imported
Gene namesi
Name:EEF1GImported
ORF Names:hCG_2039458Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27649.

PTM / Processingi

Proteomic databases

MaxQBiQ53YD7.

Expressioni

Gene expression databases

BgeeiENSG00000254772.
ExpressionAtlasiQ53YD7. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ53YD7. 1 interactor.
MINTiMINT-4999564.

Structurei

3D structure databases

SMRiQ53YD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 87GST N-terminalInterPro annotationAdd BLAST86
Domaini88 – 216GST C-terminalInterPro annotationAdd BLAST129
Domaini276 – 437EF-1-gamma C-terminalInterPro annotationAdd BLAST162

Phylogenomic databases

eggNOGiKOG0867. Eukaryota.
KOG1627. Eukaryota.
COG0625. LUCA.
HOVERGENiHBG051444.
KOiK03233.
OMAiDYEVYDW.
OrthoDBiEOG091G06QR.

Family and domain databases

Gene3Di3.30.70.1010. 1 hit.
InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
IPR001662. Transl_elong_EF1_G_con.
PfamiView protein in Pfam
PF00647. EF1G. 1 hit.
PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
SMARTiView protein in SMART
SM01183. EF1G. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
SSF89942. SSF89942. 1 hit.
PROSITEiView protein in PROSITE
PS50040. EF1G_C. 1 hit.
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53YD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL
60 70 80 90 100
RKFPAGKVPA FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS
110 120 130 140 150
FADSDIVPPA STWVFPTLGI MHHNKQATEN AKEEVRRILG LLDAYLKTRT
160 170 180 190 200
FLVGERVTLA DITVVCTLLW LYKQVLEPSF RQAFPNTNRW FLTCINQPQF
210 220 230 240 250
RAVLGEVKLC EKMAQFDAKK FAETQPKKDT PRKEKGSREE KQKPQAERKE
260 270 280 290 300
EKKAAAPAPE EEMDECEQAL AAEPKAKDPF AHLPKSTFVL DEFKRKYSNE
310 320 330 340 350
DTLSVALPYF WEHFDKDGWS LWYSEYRFPE ELTQTFMSCN LITGMFQRLD
360 370 380 390 400
KLRKNAFASV ILFGTNNSSS ISGVWVFRGQ ELAFPLSPDW QVDYESYTWR
410 420 430
KLDPGSEETQ TLVREYFSWE GAFQHVGKAF NQGKIFK
Length:437
Mass (Da):50,119
Last modified:May 24, 2005 - v1
Checksum:iA6110663110CF3FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei437Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT006677 mRNA. Translation: AAP35323.1.
AY542307 mRNA. Translation: AAT08176.1.
CR407625 mRNA. Translation: CAG28553.1.
CH471076 Genomic DNA. Translation: EAW74025.1.
RefSeqiNP_001395.1. NM_001404.4.
UniGeneiHs.144835.
Hs.444467.

Genome annotation databases

GeneIDi1937.
KEGGihsa:1937.
UCSCiuc001ntm.2. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ53YD7_HUMAN
AccessioniPrimary (citable) accession number: Q53YD7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.