Q53YD1 (Q53YD1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA-damage-inducible transcript 3 EMBL AAP35337.1

Submitted name:
DNA-damage-inducible transcript 3, isoform CRA_a EMBL EAW97021.1
Submitted name:
cDNA, FLJ94723, Homo sapiens DNA-damage-inducible transcript 3 (DDIT3), mRNA EMBL BAG38169.1

Gene names

Name:	DDIT3 EMBL EAW97021.1
ORF Names:	hCG_39661 EMBL EAW97021.1

Organism

Homo sapiens (Human) EMBL AAP35337.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	ER overload response Inferred from electronic annotation. Source: Compara blood vessel maturation Inferred from electronic annotation. Source: Compara endoplasmic reticulum unfolded protein response Inferred from electronic annotation. Source: Compara intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Inferred from electronic annotation. Source: Compara negative regulation of canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of determination of dorsal identity Inferred from electronic annotation. Source: Compara negative regulation of myoblast differentiation Inferred from electronic annotation. Source: Compara negative regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara positive regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara regulation of transcription involved in anterior/posterior axis specification Inferred from electronic annotation. Source: Compara release of sequestered calcium ion into cytosol Inferred from electronic annotation. Source: Compara
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q53YD1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 31905293FB1FBBE2	FASTA	169	19,175
	10 20 30 40 50 60 MAAESLPFSF GTLSSWELEA WYEDLQEVLS SDENGGTYVS PPGNEEEESK IFTTLDPASL 70 80 90 100 110 120 AWLTEEEPEP AEVTSTSQSP HSPDSSQSSL AQEEEEEDQG RTRKRKQSGH SPARAGKQRM 130 140 150 160 KEKEQENERK VAQLAEENER LKQEIERLTR EVEATRRALI DRMVNLHQA

References

[1]	"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector." Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Skeletal muscle EMBL BAG38169.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT006691 mRNA. Translation: AAP35337.1. AK316581 mRNA. Translation: BAG38169.1. CH471054 Genomic DNA. Translation: EAW97021.1.
IPI	IPI00019956.
RefSeq	NP_001181985.1. NM_001195056.1. NP_001181986.1. NM_001195057.1. NP_004074.2. NM_004083.5.
UniGene	Hs.505777.
3D structure databases
ProteinModelPortal	Q53YD1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q53YD1.
Proteomic databases
PRIDE	Q53YD1.
Protocols and materials databases
DNASU	1649.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1649.
KEGG	hsa:1649.
Organism-specific databases
CTD	1649.
PharmGKB	PA27193.
Phylogenomic databases
HOVERGEN	HBG051328.
KO	K04452.
PhylomeDB	Q53YD1.
Gene expression databases
ArrayExpress	Q53YD1.
Bgee	Q53YD1.
Family and domain databases
InterPro	IPR004827. bZIP. IPR016670. DNA_damage_induc_transcript_3. [Graphical view]
PANTHER	PTHR16833. PTHR16833. 1 hit.
Pfam	PF07716. bZIP_2. 1 hit. [Graphical view]
PIRSF	PIRSF016571. C/EBPzeta_CHOP_DDIT3. 1 hit.
SMART	SM00338. BRLZ. 1 hit. [Graphical view]
PROSITE	PS50217. BZIP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	DDIT3. human.
GenomeRNAi	1649.
NextBio	6792.

Entry information

Entry name

Q53YD1_HUMAN

Accession

Primary (citable) accession number: Q53YD1

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.