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Protein
Submitted name:

Parathyroid hormone-like hormone

Gene

PTHLH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Parathyroid hormone-like hormoneImported
Submitted name:
Parathyroid hormone-like hormone, isoform CRA_aImported
Submitted name:
cDNA, FLJ94023, Homo sapiens parathyroid hormone-like hormone (PTHLH), mRNAImported
Gene namesi
Name:PTHLHImported
ORF Names:hCG_37265Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33952.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500878072825 – 175Sequence analysisAdd BLAST151

Expressioni

Gene expression databases

BgeeiENSG00000087494.
ExpressionAtlasiQ53XY9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000379213.

Structurei

3D structure databases

ProteinModelPortaliQ53XY9.
SMRiQ53XY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IW2I. Eukaryota.
ENOG41126XH. LUCA.
HOGENOMiHOG000115765.
HOVERGENiHBG003236.

Family and domain databases

InterProiView protein in InterPro
IPR003626. PTH-rel.
IPR001415. PTH/PTH-rel.
PANTHERiPTHR17223. PTHR17223. 1 hit.
PfamiView protein in Pfam
PF01279. Parathyroid. 1 hit.
SMARTiView protein in SMART
SM00087. PTH. 1 hit.
PROSITEiView protein in PROSITE
PS00335. PARATHYROID. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53XY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRRLVQQWS VAVFLLSYAV PSCGRSVEGL SRRLKRAVSE HQLLHDKGKS
60 70 80 90 100
IQDLRRRFFL HHLIAEIHTA EIRATSEVSP NSKPSPNTKN HPVRFGSDDE
110 120 130 140 150
GRYLTQETNK VETYKEQPLK TPGKKKKGKP GKRKEQEKKK RRTRSAWLDS
160 170
GVTGSGLEGD HLSDTSTTSL ELDSR
Length:175
Mass (Da):19,901
Last modified:May 24, 2005 - v1
Checksum:i4FEE954C51DB3E7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007178 mRNA. Translation: AAP35842.1.
AK313476 mRNA. Translation: BAG36261.1.
CH471094 Genomic DNA. Translation: EAW96572.1.
CH471094 Genomic DNA. Translation: EAW96576.1.
RefSeqiNP_002811.1. NM_002820.2.
NP_945315.1. NM_198964.1.
UniGeneiHs.591159.

Genome annotation databases

GeneIDi5744.
UCSCiuc001rim.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007178 mRNA. Translation: AAP35842.1.
AK313476 mRNA. Translation: BAG36261.1.
CH471094 Genomic DNA. Translation: EAW96572.1.
CH471094 Genomic DNA. Translation: EAW96576.1.
RefSeqiNP_002811.1. NM_002820.2.
NP_945315.1. NM_198964.1.
UniGeneiHs.591159.

3D structure databases

ProteinModelPortaliQ53XY9.
SMRiQ53XY9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000379213.

Protocols and materials databases

DNASUi5744.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5744.
UCSCiuc001rim.4. human.

Organism-specific databases

CTDi5744.
PharmGKBiPA33952.

Phylogenomic databases

eggNOGiENOG410IW2I. Eukaryota.
ENOG41126XH. LUCA.
HOGENOMiHOG000115765.
HOVERGENiHBG003236.

Miscellaneous databases

GenomeRNAii5744.

Gene expression databases

BgeeiENSG00000087494.
ExpressionAtlasiQ53XY9. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR003626. PTH-rel.
IPR001415. PTH/PTH-rel.
PANTHERiPTHR17223. PTHR17223. 1 hit.
PfamiView protein in Pfam
PF01279. Parathyroid. 1 hit.
SMARTiView protein in SMART
SM00087. PTH. 1 hit.
PROSITEiView protein in PROSITE
PS00335. PARATHYROID. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ53XY9_HUMAN
AccessioniPrimary (citable) accession number: Q53XY9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: April 12, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.