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Unreviewed, UniProtKB/TrEMBL Q53XS4 (Q53XS4_HUMAN)

Last modified February 9, 2010. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Protein tyrosine phosphatase, non-receptor type 6 EMBL AAP36054.1
Submitted name:
    Protein tyrosine phosphatase, non-receptor type 6, isoform CRA_c EMBL EAW88702.1
    cDNA, FLJ93911, Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2, mRNA EMBL BAG36177.1
Gene names
Name: PTPN6 EMBL EAW88702.1
ORF Names: hCG_25941 EMBL EAW88702.1
OrganismHomo sapiens (Human) EMBL AAP36054.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length597 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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Sequences

Sequence LengthMass (Da)Tools
Q53XS4-1 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 6A291A2860159389

FASTA59767,719
        10         20         30         40         50         60 
MLSRGWFHRD LSGLDAETLL KGRGVHGSFL ARPSRKNQGD FSLSVRVGDQ VTHIRIQNSG 

        70         80         90        100        110        120 
DFYDLYGGEK FATLTELVEY YTQQQGVLQD RDGTIIHLKY PLNCSDPTSE RWYHGHMSGG 

       130        140        150        160        170        180 
QAETLLQAKG EPWTFLVRES LSQPGDFVLS VLSDQPKAGP GSPLRVTHIK VMCEGGRYTV 

       190        200        210        220        230        240 
GGLETFDSLT DLVEHFKKTG IEEASGAFVY LRQPYYATRV NAADIENRVL ELNKKQESED 

       250        260        270        280        290        300 
TAKAGFWEEF ESLQKQEVKN LHQRLEGQRP ENKGKNRYKN ILPFDHSRVI LQGRDSNIPG 

       310        320        330        340        350        360 
SDYINANYIK NQLLGPDENA KTYIASQGCL EATVNDFWQM AWQENSRVIV MTTREVEKGR 

       370        380        390        400        410        420 
NKCVPYWPEV GMQRAYGPYS VTNCGEHDTT EYKLRTLQVS PLDNGDLIRE IWHYQYLSWP 

       430        440        450        460        470        480 
DHGVPSEPGG VLSFLDQINQ RQESLPHAGP IIVHCSAGIG RTGTIIVIDM LMENISTKGL 

       490        500        510        520        530        540 
DCDIDIQKTI QMVRAQRSGM VQTEAQYKFI YVAIAQFIET TKKKLEVLQS QKGQESEYGN 

       550        560        570        580        590 
ITYPPAMKNA HAKASRTSSK HKEDVYENLH TKNKREEKVK KQRSADKEKS KGSLKRK

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References

[1]"Cloning of human full-length CDSs in BD Creator(TM) System Donor vector."
Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]"NEDO functional analysis of protein and research application project."
Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Liver EMBL BAG36177.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BT007390 mRNA. Translation: AAP36054.1.
AK313379 mRNA. Translation: BAG36177.1.
CH471116 Genomic DNA. Translation: EAW88702.1.
IPIIPI00396552.
RefSeqNP_536858.1.
UniGeneHs.63489

3D structure databases

SMRQ53XS4. Positions 6-528.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ53XS4.

Proteomic databases

PRIDEQ53XS4.

Genome annotation databases

EnsemblENST00000399448; ENSP00000382376; ENSG00000111679; Homo sapiens. [Genome view]
GeneID5777.
UCSCuc001qsa.1. human.

Organism-specific databases

CTD5777.
HGNCHGNC:9658. PTPN6.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ53XS4.

Gene expression databases

ArrayExpressQ53XS4.
BgeeQ53XS4.

Family and domain databases

InterProIPR000387. Dual-sp/Tyr_phosphatase.
IPR000980. SH2.
IPR016130. Tyr_Pase_AS.
IPR012152. Tyr_Pase_non-rcpt_typ-6/11.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
Gene3DG3DSA:3.30.505.10. SH2. 2 hits.
PfamPF00017. SH2. 2 hits.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PIRSFPIRSF000929. Tyr-Ptase_nr_6. 1 hit.
PRINTSPR00700. PRTYPHPHTASE.
PR00401. SH2DOMAIN.
SMARTSM00194. PTPc. 1 hit.
SM00252. SH2. 2 hits.
[Graphical view]
PROSITEPS50001. SH2. 2 hits.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio22466.
PMAP-CutDBQ53XS4.

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Entry information

Entry nameQ53XS4_HUMAN
AccessionPrimary (citable) accession number: Q53XS4
Entry history
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: February 9, 2010
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information