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Protein
Submitted name:

Ectodermal-neural cortex (With BTB-like domain)

Gene

ENC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ectodermal-neural cortex (With BTB-like domain)Imported
Submitted name:
cDNA FLJ39259 fis, clone OCBBF2009301, highly similar to Ectoderm-neural cortex 1 proteinImported
Submitted name:
cDNA, FLJ92986, Homo sapiens ectodermal-neural cortex (with BTB-like domain)(ENC1), mRNAImported
Gene namesi
Name:ENC1Imported
ORF Names:hCG_37104Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27782.

Expressioni

Gene expression databases

BgeeiENSG00000171617.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000306356.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 114BTB (POZ)InterPro annotationAdd BLAST69

Sequence similaritiesi

Contains 1 BTB (POZ) domain.UniRule annotation

Keywords - Domaini

Kelch repeatSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
HOVERGENiHBG000905.
KOiK10462.
OMAiLDAWNSI.
OrthoDBiEOG091G03JU.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR030562. ENC1.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PANTHERiPTHR24410:SF5. PTHR24410:SF5. 1 hit.
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 4 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53XS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSVHENRK SRASSGSINI YLFHKSSYAD SVLTHLNLLR QQRLFTDVLL
60 70 80 90 100
HAGNRTFPCH RAVLAACSRY FEAMFSGGLK ESQDSEVNFD NSIHPEVLEL
110 120 130 140 150
LLDYAYSSRV IINEENAESL LEAGDMLEFQ DIRDACAEFL EKNLHPTNCL
160 170 180 190 200
GMLLLSDAHQ CTKLYELSWR MCLSNFQTIR KNEDFLQLPQ DMVVQLLSSE
210 220 230 240 250
ELETEDERLV YESAINWISY DLKKRYCYLP ELLQTVRLAL LPAIYLMENV
260 270 280 290 300
AMEELITKQR KSKEIVEEAI RCKLKILQND GVVTSLCARP RKTGHALFLL
310 320 330 340 350
GGQTFMCDKL YLVDQKAKEI IPKADIPSPR KEFSACAIGC KVYITGGRGS
360 370 380 390 400
ENGVSKDVWV YDTLHEEWSK AAPMLVARFG HGSAELKHCL YVVGGHTAAT
410 420 430 440 450
GCLPASPSVS LKQVEHYDPT INKWTMVAPL REGVSNAAVV SAKLKLFAFG
460 470 480 490 500
GTSVSHDKLP KVQCYDQCEN RWTVPATCPQ PWRYTAAAVL GNQIFIMGGD
510 520 530 540 550
TEFSACSAYK FNSETYQWTK VGDVTAKRMS CHAVASGNKL YVVGGYFGIQ
560 570 580
RCKTLDCYDP TLDVWNSITT VPYSLIPTAF VSTWKHLPS
Length:589
Mass (Da):66,130
Last modified:May 24, 2005 - v1
Checksum:iDB003A1DFA65BAA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007392 mRNA. Translation: AAP36056.1.
AK312608 mRNA. Translation: BAG35496.1.
AK096578 mRNA. Translation: BAG53327.1.
CH471084 Genomic DNA. Translation: EAW95740.1.
RefSeqiNP_001243503.1. NM_001256574.1.
NP_001243504.1. NM_001256575.1.
NP_001243505.1. NM_001256576.1.
NP_003624.1. NM_003633.3.
XP_011541998.1. XM_011543696.2.
XP_011541999.1. XM_011543697.2.
UniGeneiHs.104925.
Hs.744844.

Genome annotation databases

GeneIDi8507.
KEGGihsa:8507.
UCSCiuc003kdc.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007392 mRNA. Translation: AAP36056.1.
AK312608 mRNA. Translation: BAG35496.1.
AK096578 mRNA. Translation: BAG53327.1.
CH471084 Genomic DNA. Translation: EAW95740.1.
RefSeqiNP_001243503.1. NM_001256574.1.
NP_001243504.1. NM_001256575.1.
NP_001243505.1. NM_001256576.1.
NP_003624.1. NM_003633.3.
XP_011541998.1. XM_011543696.2.
XP_011541999.1. XM_011543697.2.
UniGeneiHs.104925.
Hs.744844.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000306356.

Protocols and materials databases

DNASUi8507.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8507.
KEGGihsa:8507.
UCSCiuc003kdc.5. human.

Organism-specific databases

CTDi8507.
PharmGKBiPA27782.

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
HOVERGENiHBG000905.
KOiK10462.
OMAiLDAWNSI.
OrthoDBiEOG091G03JU.

Miscellaneous databases

ChiTaRSiENC1. human.
GenomeRNAii8507.

Gene expression databases

BgeeiENSG00000171617.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR030562. ENC1.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PANTHERiPTHR24410:SF5. PTHR24410:SF5. 1 hit.
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 4 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53XS2_HUMAN
AccessioniPrimary (citable) accession number: Q53XS2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.